Results 31 to 40 of about 189,272 (301)

Metabolomics of a Superorganism [PDF]

open access: yesThe Journal of Nutrition, 2007
The human can be thought of as a human-microbe hybrid, and the health of this superorganism will be affected by intrinsic properties such as human genetics, diurnal cycles, and age and by extrinsic factors such as lifestyle choices (food and drink, drug intake) and the acquisition of a stable "healthy" gut microflora (the so-called microbiome ...
openaire   +4 more sources

Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition. [PDF]

open access: yes, 2017
The purpose of this study was to use liquid chromatography-mass spectrometry (LC-MS) with XCMS for a quantitative metabolomic analysis of UM1 and UM2 oral cancer cells after knockdown of metabolic enzyme adenylate kinase 2 (AK2) or phosphorylate glycerol
Cheng, Siliangyu   +6 more
core   +1 more source

Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei [PDF]

open access: yes, 2013
n vitro culture methods underpin many experimental approaches to biology and drug discovery. The modification of established cell culture methods to make them more biologically relevant or to optimize growth is traditionally a laborious task.
Alsford   +58 more
core   +2 more sources

Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator

open access: yesEBioMedicine, 2016
AMP-activated protein kinase (AMPK) is suppressed in diabetes and may be due to a high ATP/AMP ratio, however the quantitation of nucleotides in vivo has been extremely difficult. Via matrix-assisted laser desorption/ionization mass spectrometry imaging (
Satoshi Miyamoto   +10 more
doaj   +1 more source

Hemolymph Metabolism Analysis of Honey Bee (Apis mellifera L.) Response to Different Bee Pollens

open access: yesInsects, 2022
Pollen is essential to the development of honey bees. The nutrients in bee pollen vary greatly among plant species. Here, we analyzed the differences in the amino acid compositions of pear (Pyrus bretschneideri), rape (Brassica napus), and apricot ...
Hongcai Chang   +4 more
doaj   +1 more source

A phytochemical comparison of saw palmetto products using gas chromatography and (1) H nuclear magnetic resonance spectroscopy metabolomic profiling [PDF]

open access: yes, 2014
© 2014 The Authors. Journal of Pharmacy and Pharmacology published by John Wiley & Sons Ltd on behalf of Royal Pharmaceutical Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use ...
Booker, Anthony   +6 more
core   +1 more source

Cell Metabolomics [PDF]

open access: yesOMICS: A Journal of Integrative Biology, 2013
Abstract Metabolomics technologies enable the examination and identification of endogenous biochemical reaction products, revealing information on the precise metabolic pathways and processes within a living cell. Metabolism is either directly or indirectly involved with every aspect of cell function, and metabolomics is thus believed
Aihua, Zhang   +4 more
openaire   +2 more sources

Proteomic and Metabolomic Profiling Elucidate the Impact of PEDV on Yorkshire Piglets and Reveal the Underlying Molecular Mechanism of PEDV Response

open access: yesAgriculture, 2023
Porcine epidemic diarrhea virus (PEDV) is an RNA virus causing acute diarrhea, vomiting, dehydration and high mortality in piglets, and poses significant challenges for the global pig industry.
Lijun Shi   +3 more
doaj   +1 more source

Metabolomics application in maternal-fetal medicine [PDF]

open access: yes, 2013
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L   +4 more
core   +4 more sources

Metabolomics in Otorhinolaryngology

open access: yesFrontiers in Molecular Biosciences, 2022
Otorhinolaryngology (Ear, Nose and Throat-ENT) focuses on inflammatory, immunological, infectious, and neoplastic disorders of the head and neck and on their medical and surgical therapy. The fields of interest of this discipline are the ear, the nose and its paranasal sinuses, the oral cavity, the pharynx, the larynx, and the neck.
Noto, Antonio   +8 more
openaire   +5 more sources

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