Results 31 to 40 of about 159,394 (302)

Anthropogenic Pressure and Lifestyle are the Underlying Cause of Pandemic Chronic Diseases [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2019
Dramatic changes in the environment in recent decades have resulted in low-nutrient food and excessive intake of heavy metals and toxins through air, drinking water, and dietary habits. Non-communicable diseases (NCD), which are responsible for almost 70%
Dimitris Tsoukalas, Evangelia Sarandi, Aristides Tsatsakis, Daniela Calina   +3 more
doaj   +1 more source

The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect [PDF]

, 2016
The two human cell lines HepG2 from hepatoma and HMCL-7304 from striated muscle were γ-irradiated with doses between 0 and 4 Gy. Abundant γH2AX foci were observed at 4 Gy after 4 h of culture post-irradiation.
Idle, J. R., Treves, Susan, Treves, S., Beyoğlu, Diren, Keogh, Adrian, Wang, M., Idle, Jeffrey, Idle, Jeffrey R., Beyoğlu, D., Min Wang, Diren Beyoğlu, Wang, Min, Adrian Keogh, Susan Treves, Jeffrey R. Idle, Keogh, A.   +15 more
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Metabolomic Changes in Plasma of Preterminal Stage of Rhesus Nonhuman Primates Exposed to Lethal Dose of Radiation

, 2023
Ionizing radiation exposure is known to induce molecular and cellular injury, inflicting a cascade of potentially catastrophic events leading to tissue and organ damage.
John B. Tyburski, Vijay K. Singh, Stephen Y. Wise, Amrita K. Cheema, Oluseyi O. Fatanmi, Alana D. Carpenter, Sarah A. Petrus   +6 more
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Untargeted Metabolomic Assay of Prefrail Older Adults after Nutritional Intervention

, 2022
Frailty is a geriatric syndrome causing a reduction in the body’s functional reserves. Proper nutrition may be helpful in delaying transitioning older adults from pre-frail to frailty syndrome.
Jaroch, Alina, Jaroch, Karol, Alina Jaroch, Główczewska-Siedlecka, Emilia, Bojko, Barbara, Mariusz Kozakiewicz, Kornelia Kędziora-Kornatowska, Kozakiewicz, Mariusz, Karol Jaroch, Emilia Główczewska-Siedlecka, Kędziora-Kornatowska, Kornelia, Barbara Bojko   +11 more
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Extraction for Metabolomics: Access to The Metabolome

Phytochemical Analysis, 2014
ABSTRACTIntroductionThe value of information obtained from a metabolomic study depends on how much of the metabolome is present in analysed samples. Thus, only a comprehensive and reproducible extraction method will provide reliable data because the metabolites that will be measured are those that were extracted and all conclusions will be built around
Mushtaq, M.Y., Choi, Y.H., Verpoorte, R., Wilson, E.G.   +3 more
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Targeted Metabolomics [PDF]

Current Protocols in Molecular Biology, 2012
AbstractThe metabolome is the terminal downstream product of the genome and consists of the total complement of all the low‐molecular‐weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states.
Lee D, Roberts, Amanda L, Souza, Robert E, Gerszten, Clary B, Clish   +3 more
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Polymorphie DNA repair genes XRCC1 and XRCC3 and the risk for cervical cancer in Brazilian patients

Brazilian Journal of Oncology, 2017
Background: DNA repair genes play a key role in maintaining genomic stability and integrity. DNA repair gene polymorphisms, such as X-ray repair cross-complementing group 1 and 3 genes (XRCC1 and XRCC3), are implicated to contribute to ...
Fabricio Colacino-Silva, João Paulo Ferreira de Oliveira Kleine, Márcia Batista Salzgeber, Rodrigo de Aquino Castro, Manoel João Batista Castello Girão, Ismael Dale Cotrim Guerreiro da Silva, Paulo D’Amora   +6 more
doaj   +1 more source

Comparative Evaluation of Plasma Metabolomic Data from Multiple Laboratories

, 2022
In mass spectrometry-based metabolomics, the differences in the analytical results from different laboratories/machines are an issue to be considered because various types of machines are used in each laboratory.
Fumie Hamano, Daisuke Saigusa, Suzumi M. Tokuoka, Masaru Yoshida, Nobuyuki Okahashi, Hiroki Nakanishi, Motonao Nakao, Yoshihiro Kita, Kosuke Saito, Masami Yokota Hirai, Yoshiya Oda, Akiyoshi Hirayama, Takeshi Bamba, Naomi Matsukawa, Masatomo Takahashi, Fumio Matsuda, Eiji Hishinuma, Kazutaka Ikeda, Shin Nishiumi, Yoshihiro Izumi, Kosuke Hata   +20 more
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Metabolomics in Otorhinolaryngology

Frontiers in Molecular Biosciences, 2022
Otorhinolaryngology (Ear, Nose and Throat-ENT) focuses on inflammatory, immunological, infectious, and neoplastic disorders of the head and neck and on their medical and surgical therapy. The fields of interest of this discipline are the ear, the nose and its paranasal sinuses, the oral cavity, the pharynx, the larynx, and the neck.
Noto, Antonio, Piras, Cristina, Atzori, Luigi, Mussap, Michele, Albera, Andrea, Albera, Roberto, Casani, Augusto Pietro, Capobianco, Silvia, Fanos, Vassilios   +8 more
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An inter-laboratory comparison demonstrates that [H-1]-NMR metabolite fingerprinting is a robust technique for collaborative plant metabolomic data collection. [PDF]

, 2010
In any metabolomics experiment, robustness and reproducibility of data collection is of vital importance. These become more important in collaborative studies where data is to be collected on multiple instruments.
Biais, Benoit, Beale, Michael H., Sofia Moco, Jacques Vervoort, Maucourt, Mickael,, Ward, J.L., Michael H. Beale, Lommen, Arjen, Rolin, D., Maucourt, Mickael, M., Moco, Sofia, Vervoort, J., Baker, J. M., Humpfer, Eberhard, Deborde, C., Beale, M.H., Ward, J. L., Deborde, Catherine,, Maucourt, M., Mickael Maucourt, Beale, M. H., Annick Moing, Lommen, A., Jane L. Ward, Vervoort, J.J.M., Hartmut Schäfer, Schäfer, Hartmut, Deborde, Catherine, Baker, J.M., Arjen Lommen, Miller, S.J., Vervoort, Jacques, Eberhard Humpfer, Miller, Sonia J., Rolin, Dominique, D., Moco, S.I.A., Rolin, Dominique,, John M. Baker, Baker, John M., Benoit Biais, Catherine Deborde, Moco, S., Ward, Jane L., Biais, B., Dominique Rolin, Moing, Annick, Humpfer, E., Moing, A., Miller, S. J., Sonia J. Miller, Schafer, H.   +50 more
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