Results 31 to 40 of about 168,925 (309)

Metabolomics of a Superorganism [PDF]

The Journal of Nutrition, 2007
The human can be thought of as a human-microbe hybrid, and the health of this superorganism will be affected by intrinsic properties such as human genetics, diurnal cycles, and age and by extrinsic factors such as lifestyle choices (food and drink, drug intake) and the acquisition of a stable "healthy" gut microflora (the so-called microbiome ...
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Hemolymph Metabolism Analysis of Honey Bee (Apis mellifera L.) Response to Different Bee Pollens

Insects, 2022
Pollen is essential to the development of honey bees. The nutrients in bee pollen vary greatly among plant species. Here, we analyzed the differences in the amino acid compositions of pear (Pyrus bretschneideri), rape (Brassica napus), and apricot ...
Hongcai Chang, Guiling Ding, Guangqun Jia, Mao Feng, Jiaxing Huang   +4 more
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Untargeted Metabolomic Assay of Prefrail Older Adults after Nutritional Intervention

, 2022
Frailty is a geriatric syndrome causing a reduction in the body’s functional reserves. Proper nutrition may be helpful in delaying transitioning older adults from pre-frail to frailty syndrome.
Jaroch, Alina, Jaroch, Karol, Alina Jaroch, Główczewska-Siedlecka, Emilia, Bojko, Barbara, Mariusz Kozakiewicz, Kornelia Kędziora-Kornatowska, Kozakiewicz, Mariusz, Karol Jaroch, Emilia Główczewska-Siedlecka, Kędziora-Kornatowska, Kornelia, Barbara Bojko   +11 more
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Metabolomics and Atherosclerosis [PDF]

Current Atherosclerosis Reports, 2010
Metabolites reflect the dynamic processes underlying cellular homeostasis. Recent advances in analytical chemistry and molecular biology have set the stage for metabolite profiling to help us understand complex molecular processes and physiology. Metabolomics is the comparative analysis of metabolite flux and how it relates to biological phenotypes. As
Sascha N, Goonewardena, Lisa E, Prevette, Ankit A, Desai   +2 more
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Mass Spectrometry Imaging Reveals Elevated Glomerular ATP/AMP in Diabetes/obesity and Identifies Sphingomyelin as a Possible Mediator

EBioMedicine, 2016
AMP-activated protein kinase (AMPK) is suppressed in diabetes and may be due to a high ATP/AMP ratio, however the quantitation of nucleotides in vivo has been extremely difficult. Via matrix-assisted laser desorption/ionization mass spectrometry imaging (
Satoshi Miyamoto, Cheng-Chih Hsu, Gregory Hamm, Manjula Darshi, Maggie Diamond-Stanic, Anne-Emilie Declèves, Larkin Slater, Subramaniam Pennathur, Jonathan Stauber, Pieter C. Dorrestein, Kumar Sharma   +10 more
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Proteomic and Metabolomic Profiling Elucidate the Impact of PEDV on Yorkshire Piglets and Reveal the Underlying Molecular Mechanism of PEDV Response

Agriculture, 2023
Porcine epidemic diarrhea virus (PEDV) is an RNA virus causing acute diarrhea, vomiting, dehydration and high mortality in piglets, and poses significant challenges for the global pig industry.
Lijun Shi, Huihui Li, Chunxiang Zhou, Lixian Wang   +3 more
doaj   +1 more source

Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition [PDF]

, 2011
The quantification of experimentally-induced alterations in biological pathways remains a major challenge in systems biology. One example of this is the quantitative characterization of alterations in defined, established metabolic pathways from complex ...
Dawson, Neil, MacIntyre, Lynsey, Xiao, Xiaolin, Watson, David, Higham, Desmond, Pratt, Judith, Morris, Brian   +6 more
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Comparative Evaluation of Plasma Metabolomic Data from Multiple Laboratories

, 2022
In mass spectrometry-based metabolomics, the differences in the analytical results from different laboratories/machines are an issue to be considered because various types of machines are used in each laboratory.
Fumie Hamano, Daisuke Saigusa, Suzumi M. Tokuoka, Masaru Yoshida, Nobuyuki Okahashi, Hiroki Nakanishi, Motonao Nakao, Yoshihiro Kita, Kosuke Saito, Masami Yokota Hirai, Yoshiya Oda, Akiyoshi Hirayama, Takeshi Bamba, Naomi Matsukawa, Masatomo Takahashi, Fumio Matsuda, Eiji Hishinuma, Kazutaka Ikeda, Shin Nishiumi, Yoshihiro Izumi, Kosuke Hata   +20 more
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Metabolomic epidemiology offers insights into disease aetiology [PDF]

, 2023
Metabolomic epidemiology is the high-throughput study of the relationship between metabolites and health-related traits. This emerging and rapidly growing field has improved our understanding of disease aetiology and contributed to advances in precision ...
Sachelly Julián-Serrano, Nicholas, Jayna, Drzymalla, Emily M, Raffield, Laura M, Harriett Fuller, Sarvestani, Afrand K, Nasa Sinnott-Armstrong, Usman A. Tahir, Katherine H. Shutta, Chatelaine, Haley A, Yiwen Zhu, Rahnavard, Ali, Afrand K. Sarvestani, Emily M. Drzymalla, Jayna Nicholas, Ali Rahnavard, Darst, Burcu F, Shutta, Katherine H, Fuller, Harriett, Laura M. Raffield, Julián-Serrano, Sachelly, Sinnott-Armstrong, Nasa, Hua, Xinwei, Zhu, Yiwen, Tahir, Usman A, Haley A. Chatelaine, Xinwei Hua, Burcu F. Darst   +27 more
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Stability of Metabolomic Content during Sample Preparation: Blood and Brain Tissues

, 2022
Thermal and enzymatic reactions can significantly change the tissue metabolomic content during the sample preparation. In this work, we evaluated the stability of metabolites in human whole blood, serum, and rat brain, as well as in metabolomic extracts ...
Lyudmila V. Yanshole, Tsentalovich, Yuri P., Maxim V. Fomenko, Yuri P. Tsentalovich, Fomenko, Maxim V., Yanshole, Lyudmila V.   +5 more
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