Results 81 to 90 of about 6,252 (250)

Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in Gabon

, 2020
Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in ...
Isabella Eckerle (381546), Samuel Cordey (74802), Martin Peter Grobusch (9287756), Benjamin Mordmüller (211841), Florian Laubscher (6535340), José Francisco Fernandes (9287753), Mylène Docquier (105372), Laurent Kaiser (74805), Jana Held (224956)   +8 more
core   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Pathogenic Detection by Metagenomic next-generation Sequencing in Spinal Infections

Spine
Study Design. Retrospective, observational study. Objective. To evaluate the ability and value of metagenomic next-generation sequencing (mNGS) in detecting pathogens from spinal infections. Background.
Chuqiang Yin, Yanan Cong, Huafeng Wang, Dechun Wang, Xizhong Yang, Xuesong Wang, Ting Wang   +6 more
openaire   +2 more sources

Anti‐inflammatory and osteogenic effects of transcutaneous electrical nerve stimulation in knee osteoarthritis rats via the regulation of the intestinal microbiota

Animal Models and Experimental Medicine, EarlyView.
Transcutaneous electrical nerve stimulation (TENS) improved knee osteoarthritis (KOA) in rats by regulating interleukin‐1β (IL‐1β), IL‐6, and IL‐8 expressions and the bone morphogenetic protein 2 (BMP‐2)/transforming growth factor β (TGF‐β) signaling pathway.
Yan Sun, Tong Ma, Ran Chen, Lan Shen, Xun Tang, Zhiqiang Shen, Hongbin Zhao   +6 more
wiley   +1 more source

Coxiella burnetii and Bartonella Endocarditis Diagnosed by Metagenomic Next-Generation Sequencing

, 2022
(1) Background: Culture-negative endocarditis is challenging to diagnose. Here, we retrospectively identified 23 cases of Coxiella burnetii and Bartonella endocarditis by metagenomic next-generation sequencing.
Gan, Lixi, Xin Li, Oudi Chen, Lixi Gan, Ma, Qingyan, Wang, Weiteng, Liu, Weijiang, Qingyan Ma, Chen, Oudi, Hu, Xuejiao, Li, Xin, Weijiang Liu, Weiteng Wang, Xuhua Jian, Jian, Xuhua, Xuejiao Hu   +15 more
core   +1 more source

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

Annals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh, Xochitl C. Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A. Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios   +7 more
wiley   +1 more source

Acute Pulmonary Actinomycosis Induced by Immunotherapy and Chemotherapy Used for SCLC Treatment: A Case Report and Literature Review

Infection and Drug Resistance, 2023
Ju Kuang, Zhihai Luo, Fu Zhou Department of Respiratory and Critical Care Medicine, Affiliated Banan Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Fu Zhou, Tel +86-17702395630, Email 1163629567@qq ...
Kuang J, Luo Z, Zhou F
doaj  

Clinical Value of Sampling Time of Metagenomic Next-Generation Sequencing in Patients with Severe Pneumonia

, 2023
Shixiao Li,1 Peng Zhou,2 Lihong Yang,1 Tianbin Tang,1 Jiajia Qin,1 Jiao Qian,1 Shen Bo,1 Sufei Yu1 1Department of Clinical Microbiology Laboratory, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, People ...
Qian J, Li S, Yang L, Zhou P, Yu S, Qin J, Tang T, Bo S   +7 more
core  

Metagenomic Next-Generation Sequencing versus Traditional Pathogen Detection in the Diagnosis of Peripheral Pulmonary Infectious Lesions

Infection and Drug Resistance, 2020
Jie Huang,1,2 Erlie Jiang,3 Donglin Yang,3 Jialin Wei,3 Mingfeng Zhao,4 Jing Feng,1 Jie Cao1 1Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China; 2Graduate School ...
Huang J, Jiang E, Yang D, Wei J, Zhao M, Feng J, Cao J   +6 more
doaj  

Rapid Pathogen Detection in Infectious Uveitis Using Nanopore Metagenomic Next-Generation Sequencing: A Preliminary Study

, 2023
We establish an accurate and rapid diagnostic method for pathogen detection in infectious uveitis using nanopore metagenomic next-generation sequencing (NGS). In eight patients with suspected infectious uveitis, we prospectively compared the accuracy and
Eun Young Choi (338189), Suk Ho Byeon (9327412), Junwon Lee (2232541), Hyun Goo Kang (3949904), Christopher Seungkyu Lee (2630512), Han Jeong (3525500), Jinkyu Park (1324137), Min Kim (218786)   +7 more
core   +1 more source