Results 81 to 90 of about 4,663,034 (296)

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources

Binning and annotation for metagenomic next-generation sequencing reads

, 2015
The development of next-generation sequencing technology enables us to obtain a vast number of short reads from metagenomic samples. In metagenomic samples, the reads from different species are mixed together. So, metagenomic binning has been introduced to cluster reads from the same or closely related species and metagenomic annotation is introduced ...
openaire   +3 more sources

Metagenomic Next-Generation Sequencing Direct Diagnosis of Mixed Bacterial Meningitis in a Child: A Case Report [PDF]

Wei Wang,* Yujuan Wang,* Xiaowei Xin, Yi Yin, Chun Zhao, Youpeng Jin Department of Pediatric Intensive Care Unit, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, 250021, People’s Republic of
Yin Y, Zhao C, Wang W, Wang Y, Xin X, Jin Y   +5 more
core  

EBI metagenomics—a new resource for the analysis and archiving of metagenomic data [PDF]

, 2013
Metagenomics is a relatively recently established but rapidly expanding field that uses high-throughput next-generation sequencing technologies to characterize the microbial communities inhabiting different ecosystems (including oceans, lakes, soil ...
Vaughan, Daniel, Mitchell, Alex, Field, Dawn, Gonzalez-Beltran, Alejandra, Scheremetjew, Maxim, McAnulla, Craig, Sansone, Susanna-Assunta, Sterk, Peter, Radhakrishnan, Rajesh, Hunter, Sarah, Leinonen, Rasko, Jones, Philip, Jones Philip, Denise, Hubert, Cochrane, Guy, Maslen, John, Oisel, Arnaud, Pesseat, Sebastien, Hubert, Denise, Corbett, Matthew, Fraser, Matthew, Rocca-Serra, Philippe, Hunter, Christopher, Michell, Alex, Maguire, Eamonn, Gift, Nuka, Nuka, Gift   +26 more
core   +2 more sources

Rainfall Shapes the Diversity of Soil Nitrogen‐Fixing Microorganisms Worldwide

Advanced Science, EarlyView.
This study reveals the distinctive pattern and mechanism of rainfall driving the global biodiversity and biogeography of soil potential N‐fixing microorganisms, and constructs the theoretical framework. The results guide us on how to maintain ecosystem productivity under future climate changes (e.g., whether a specific region needs more N fertilizers ...
Bin Hua, Shuang Pang, Ang Li, Zonghao Hu, Honghui Wu, Shuhan Zhang, Yi Fan, Yi Wu, Wei Yang, Yachao Zhao, Yupeng Guan, Baoming Ji, Deliang Kong, Yong Zhao, Anton A. Goncharov, Anastasia Yu. Korotkevich, Rong Mao, Yang Zhang, Ximei Zhang   +18 more
wiley   +1 more source

Application of Metagenomic Next-Generation Sequencing in HIV-Infected Patients with Bloodstream Infections [PDF]

Huiting Liu, Tianzhen Xu, Hongxin Fu, Bohao Dai, Yirui Xie State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of ...
Liu H, Xie Y, Dai B, Fu H, Xu T
core  

Diagnostic metagenomics : potential applications to bacterial, viral and parasitic infections [PDF]

, 2014
The term 'shotgun metagenomics' is applied to the direct sequencing of DNA extracted from a sample without culture or target-specific amplification or capture.
M. J. Pallen, Pallen, Mark J.
core   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

Case report: Chronic Candida albicans meningitis: a rare entity diagnosed by metagenomic next-generation sequencing. [PDF]

The aetiology of chronic aseptic meningitis is difficult to establish. Candida meningitis in particular is often diagnosed late, as cerebrospinal fluid (CSF) work-up and imaging findings are nonspecific.
Lazarevic, Vladimir, Z'Graggen, Werner J, Müller, Mandy D, Walti, Laura N, Schrenzel, Jacques, Oberli, Alexander, Martin, Yonas, Z Graggen, Werner J, Kuenzli, Andrea B   +8 more
core   +2 more sources