Results 41 to 50 of about 5,484 (240)

Fasting and Refeeding Mediated Phospholipid Remodeling Plays an Important Role in Improving Meat Quality of Aged Laying Hens

Animal Research and One Health, EarlyView.
ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang, Jun Zhang, Yadong Tian, Donghua Li, Yanhua Zhang, Lujie Zhang, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +8 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Substrate specificity and structural investigation into PepO and PepW : two peptidases from Lactobacillus rhamnosus : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]

, 2005
The proteolytic systems of lactic acid bacteria have important roles in the maturation and flavour development of cheese. Lactic acid bacteria pepetidases contribute to the taste of cheese through the production of low-molecular weight peptides and free ...
Yates, Karen Maree
core  

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits

Aging Cell, Volume 25, Issue 2, February 2026.
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen, Jennifer L. Martindale, Martina Rossi, Chang Hoon Shin, Apala Pal, Rachel Munk, Martin Salamini‐Montemurri, Mirko Baranzini, Ethan M. Arends, Maja Mustapic, Yuta Lee, Jau‐Nan Lee, Sicco H. Popma, Justin Hu, Nathan Duda, Carlos J. Nogueras‐Ortiz, Dimitrios Kapogiannis, Chang‐Yi Cui, Myriam Gorospe   +18 more
wiley   +1 more source

Chronic tendon pathology: molecular basis and therapeutic implications [PDF]

, 2005
Tendons are frequently affected by chronic pain or rupture. Many causative factors have been implicated in the pathology, which until relatively recently was under-researched and poorly understood.
Riley, GP
core   +1 more source

Echinacoside Improves Pulmonary Vascular Remodeling by Regulating the L‐ and T‐Type Ca2+ Channels in the Prevention and Treatment of Pulmonary Hypertension

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT The typical pathology of pulmonary hypertension (PH) is characterized by pulmonary vasoconstriction and irreversible pulmonary vascular remodeling. Vascular remodeling is the process of structural changes and cellular rearrangement of blood vessels due to injury and is a significant factor in conditions such as PH.
Yuefu Zhao, Jinyu Wang, Yujie Qiao, Xiangyun Gai, Jiacheng Hu, Hongmai Wang, Qingqing Xia, Qiuqin Hu, Zhanqiang Li, Cen Li, Hongtao Bi   +10 more
wiley   +1 more source

Group Additive Regression Models for Genomic Data Analysis [PDF]

, 2006
One important problem in genomic research is to identify genomic features such as gene expression data or DNA single nucleotide polymorphisms (SNPs) that are related to clinical phenotypes.
Li, Hongzhe, Luan, Yihui
core   +1 more source

Genomic Connectivity and Adaptation Signals of the Freshwater Sponge Ephydatia muelleri Across Its Distribution

Journal of Biogeography, Volume 53, Issue 1, January 2026.
ABSTRACT Aim Genetic connectivity and local adaptation were examined across the distribution of the freshwater sponge Ephydatia muelleri. Because it occupies an exceptional breadth of freshwater environments across a broad geographic range, this species offers key insights into biogeographic processes shaping genetic structure and adaptation in inland ...
Laura de la Cruz‐Castillejo, Robert Cassidy, Konstantina Mitsi, Carles Galià‐Camps, Ana Benítez‐López, Carlota Gracia‐Sancha, Jose Lorente‐Sorolla, Almudena Álvarez‐Fernández, Rocío Mozo, Stephen Kolomyjec, Scott Nichols, Renata Manconi, Raquel Pereira, Karen Evans, Valeria Itskovich, April L. Horton, Sally P. Leys, Sergi Taboada, Ana Riesgo   +18 more
wiley   +1 more source

The immuneregulator role of neprilysin (NEP) in invertebrates [PDF]

, 2012
Neprilysin (NEP) represents an important enzyme in both vertebrates and invertebrates. In the present report we have focused our attention to invertebrates. In particular, a structure related to CD10/NEP as well as its activity in different tissues, such
A. Grimaldi, D. Malagoli, E. Ottaviani, M. de Eguileor   +3 more
core  

Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P33-42. [PDF]

, 2011
BACKGROUND: Fibrolytic and profibrotic activities of the matrix metalloproteinases (MMPs)-2 and -9 play a central role in liver fibrosis. Since binding to the extracellular matrix influences the activity of both gelatinases, here the role of fibrillar ...
Dieterich, Walburga, Erben, Ulrike, Farndale, Richard W, Freise, Christian, Muche, Marion, Neumann, Ulf, Popov, Yury, Ruehl, Martin, Schuppan, Detlef, Somasundaram, Rajan, Zeitz, Martin   +10 more
core   +3 more sources