Results 31 to 40 of about 107,753 (225)
CHIMIA, 2008 Methionine is a key amino acid that has numerous roles in essential vital processes. Moreover, methionine oxidation is biologically important during conditions of oxidative stress and represents an important step in the development of some ...
Krzysztof Bobrowski +2 more
doaj +1 more source
Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography [PDF]
Biomed. Opt. Express 13 (2022) 4071-4086, 2022 Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD) mouse liver is demonstrated ex vivo by dynamic optical coherence tomography (OCT). The NAFLD mouse is a methionine choline-deficient (MCD)-diet model, and two mice fed MCD diet for 1 and 2 weeks are involved in addition to a normal-diet mouse.
arxiv +1 more source
Voxelwise principal component analysis of dynamic [S-methyl-11C]methionine PET data in glioma patients [PDF]
, 2020 Recent works have demonstrated the added value of dynamic amino acid positron emission tomography (PET) for glioma grading and genotyping, biopsy targeting, and recurrence diagnosis. However, most of these studies are exclusively based on hand-crafted qualitative or semi-quantitative dynamic features extracted from the mean time activity curve (TAC ...
arxiv +1 more source
Maturation of Circulatory Responses to Methionine-Enkephalin [PDF]
Pediatric Research, 1983 The cardiovascular and respiratory effects of the naturally occurring endogenous opiate, methionine-enkephalin, were studied in 23 fetal sheep, five newborn lambs, 15 pregnant sheep, and four nonpregnant ewes. The opiate peptide produced dose-dependent decreases in heart rate and blood pressure in fetal and neonatal lambs but increased heart rate and ...
Abraham M. Rudolph +2 more
openaire +3 more sources
Angewandte Chemie, EarlyView.Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka +5 more
wiley +2 more sources
Protein Folding Simulations in a Deformed Energy Landscape [PDF]
Eur. Phys. J. B 12 (1999) 607-612, 2000 A modified version of stochastic tunneling, a recently introduced global optimization technique, is introduced as a new generalized-ensemble technique and tested for a benchmark peptide, Met-enkephalin.
arxiv +1 more source
Metropolis simulations of Met-Enkephalin with solvent-accessible area parameterizations [PDF]
Phys. Rev. E 69, 026703 (2004), 2003 We investigate the solvent-accessible area method by means of Metropolis simulations of the brain peptide Met-Enkephalin at 300$ K$. For the energy function ECEPP/2 nine atomic solvation parameter (ASP) sets are studied. The simulations are compared with one another, with simulations with a distance dependent electrostatic permittivity $\epsilon (r ...
arxiv +1 more source
Methionine-enkephalin and leucine-enkephalin in human sympathoadrenal system and pheochromocytoma. [PDF]
Journal of Clinical Investigation, 1982 To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with ...
Hiroo Imura +4 more
openaire +2 more sources
Cell Transplantation, 2013 Transplantation of allogeneic adrenal chromaffin cells demonstrated the promise of favorable outcomes for pain relief in patients. However, there is a very limited availability of suitable human adrenal gland tissues, genetically well-matched donors in ...
T. Qu M.D., Ph.D. +5 more
doaj +1 more source
Cell Transplantation, 2006 We have reported that transplantation of adrenal medullary chromaffin cells that release endogenous opioid peptides into pain modulatory regions in the CNS produce significant antinociceptive effects in patients with terminal cancer pain.
Ikuko Sugaya +3 more
doaj +1 more source