Results 51 to 60 of about 291,374 (170)

EFFECT OF DIETARY BETAINE AND LOW METHIONINE ON MULARD DUCK PERFORMANCE, BLOOD PARAMETERS AND LIPOGENESIS GENE EXPRESSION

Slovenian Veterinary Research, 2018
The effects of dietary methionine and betaine (Bet) on productive performance, blood biochemical parameters and mRNA expression levels of fat acid synthase (FAS) and acetyl-CoA carboxylase (ACC), were investigated in Mulard ducks which raised in summer ...
Rania El Sayed, Doaa Ibrahim, Shefaa A.M. El-Mandrawy, Doaa M. AbdelFattah   +3 more
doaj   +1 more source

Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase

Redox Biology, 2020
Acute pancreatitis is an inflammatory process of the pancreatic gland that may lead to dysregulation of the trans-sulfuration pathway. The aims of this work were firstly to study the methionine cycle as well as the trans-sulfuration pathway using ...
Sergio Rius-Pérez, Salvador Pérez, Isabel Torres-Cuevas, Pablo Martí-Andrés, Raquel Taléns-Visconti, Alberto Paradela, Laura Guerrero, Luis Franco, Gerardo López-Rodas, Luis Torres, Fernando Corrales, Juan Sastre   +11 more
doaj   +1 more source

Homocystinuria and ocular complications – A review

Indian Journal of Ophthalmology, 2022
Homocystinuria is a rare metabolic inborn disorder caused due to dysfunctional cystathionine β-synthase (CBS) enzyme activity, thus resulting in elevated levels of methionine and homocysteine in the blood and urine.
Mehzabeen Rahman, Mohita Sharma, Pragati Aggarwal, Silkee Singla, Neha Jain   +4 more
doaj   +1 more source

Methionine synthase deficiency without megaloblastic anaemia [PDF]

European Journal of Pediatrics, 1997
We report findings on a child presenting with neonatal homocystinuria, hypomethioninaemia and severe neurological symptoms, including developmental delay and seizures. Methylmalonic aciduria was not present. The activity of methionine synthase in fibroblasts was severely deficient and formation of methylcobalamin from 57Co labelled cyanocobalamin was ...
E A, Kvittingen, S, Spangen, J, Lindemans, B, Fowler   +3 more
openaire   +2 more sources

Polymorphisms in Methionine Synthase, Methionine Synthase Reductase and Serine Hydroxymethyltransferase, Folate and Alcohol Intake, and Colon Cancer Risk [PDF]

Lifestyle Genomics, 2008
<i>Background/Aims:</i> We examined associations among folate and alcohol intake, single nucleotide polymorphisms (SNPs) in genes involved in one-carbon metabolism, and colon cancer risk. <i>Methods:</i> Colon cancer cases (294 African-Americans and 349 whites) were frequency matched to population controls (437 African-Americans
Steck, Susan E., Keku, Temitope O., Butler, Lesley M., Galanko, Joseph, Massa, Beri, Millikan, Robert C., Sandler, Robert S.   +6 more
openaire   +2 more sources

Association of methionine synthase rs1801394 and methionine synthase reductase rs1805087 polymorphisms with meningioma in adults: A meta-analysis

Biomedical Reports, 2014
Several epidemiological studies suggested that methionine synthase (MTRR) rs1801394 and methionine synthase reductase (MTR) rs1805087 polymorphisms may be involved in the risk of meningioma in adults; however, the results from different case-control studies have been inconsistent.
ZENG, XIAN-TAO, LU, JUN-TI, TANG, XIANG-JUN, WENG, HONG, LUO, JIE   +4 more
openaire   +3 more sources

Methionine Supply to Growing Steers Affects Hepatic Activities of Methionine Synthase and Betaine-Homocysteine Methyltransferase, but Not Cystathionine Synthase [PDF]

The Journal of Nutrition, 2002
The effects of supplemental methionine (Met), supplied abomasally, on the activities of methionine synthase (MS), cystathionine synthase (CS) and betaine-homocysteine methyltransferase (BHMT) were studied in growing steers. Six Holstein steers (205 kg) were used in a replicated 3 x 3 Latin square experiment. Steers were fed 2.6 kg dry matter daily of a
Barry D, Lambert, Evan C, Titgemeyer, Gerald L, Stokka, Brad M, DeBey, Clint A, Löest   +4 more
openaire   +2 more sources

Polymorphism of Folate Metabolism Genes among Ethnic Kazakh Women with Preeclampsia in Kazakhstan: A Descriptive Study

Biology
Introduction: Preeclampsia is a severe multifactorial complication of pregnancy. Studies found associations between folate metabolism genes’ polymorphisms and preeclampsia. However, investigations in this field are limited among Asian populations.
Lyazzat Kaldygulova, Sauran Yerdessov, Talshyn Ukybassova, Yevgeniy Kim, Dinmukhamed Ayaganov, Andrey Gaiday   +5 more
doaj   +1 more source

The role of homocysteine and methylenetetrahydrofolate reductase, methionine synthase, methionine synthase reductase polymorphisms in the development of cardiovascular diseases and hypertension [PDF]

Orvosi Hetilap, 2012
Cardiovascular diseases (CVDs) are the leading causes of death in the developed countries. Elevated homocysteine level is as an independent risk factor of CVDs. The C677T and A1298C variants of methylenetetrahydrofolate reductase gene (MTHFR) have been shown to influence folate and homocysteine metabolisms.
Krisztina, Marosi, Annamária, Agota, Veronika, Végh, József Gábor, Joó, Zoltán, Langmár, Ildikó, Kriszbacher, Zsolt B, Nagy   +6 more
openaire   +2 more sources

Engineering of methionine-auxotroph Escherichia coli via parallel evolution of two enzymes from Corynebacterium glutamicum's direct-sulfurylation pathway enables its recovery in minimal medium

Metabolic Engineering Communications
Methionine biosynthesis relies on the sequential catalysis of multiple enzymes. Escherichia coli, the main bacteria used in research and industry for protein production and engineering, utilizes the three-step trans-sulfurylation pathway catalyzed by L ...
Matan Gabay, Inbar Stern, Nadya Gruzdev, Adi Cohen, Lucia Adriana-Lifshits, Tamar Ansbacher, Itamar Yadid, Maayan Gal   +7 more
doaj   +1 more source