Results 21 to 30 of about 154,899 (297)
METHOTREXATE USE IS SAFE IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
Folia Medica Indonesiana, 2017 Monitoring level of methotrexate is not only aimed at monitoring effectiveness, but also safety aspects of the administration of high-dose methotrexate because the use of high-dose methotrexate is one of the problems associated with toxicity in various ...
Febriansyah Nur Utomo +3 more
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EXACERBATION OF ANKYLOSING SPONDYLITIS AFTER LOW-DOSE METHOTREXATE THERAPY
Alʹmanah Kliničeskoj Mediciny, 2016 Background: Efficacy of methotrexate in ankylosing spondylitis (AS) is disputable. Nevertheless, methotrexate is still used for disease-modifying therapy of AS. Aim: To assess efficacy and safety of methotrexate in AS patients.
A. V. Orlov-Morozov
doaj +1 more source
RMD Open, 2023 Introduction We aimed to compare the proportions of patients with newly diagnosed psoriatic arthritis (PsA) and rheumatoid arthritis (RA) remaining on methotrexate (regardless of other disease-modifying antirheumatic drug (DMARD)-changes), and ...
Ulf Lindström +7 more
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Failure Rate of Single Dose Methotrexate in Managment of Ectopic Pregnancy
Obstetrics and Gynecology International, 2015 Background. One of the treatment modalities for ectopic pregnancy is methotrexate. The purpose of this study is to identify the failure rate of methotrexate in treating patients with ectopic pregnancy as well as the risk factors leading to treatment ...
Feras Sendy +5 more
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Effects of intraventricular methotrexate administration on Cuprizone-induced demyelination in mice
Frontiers in Molecular Neuroscience, 2013 We previously showed that intrathecal administration of methotrexate slowed disability progression in multiple sclerosis patients with progressive disease. In general MS patients with progressive disease respond poorly to anti-inflammatory therapies.
Andre Michael Mueller +7 more
doaj +1 more source
Effect of hydraulic conductivity and permeability on drug distribution, an investigation based on a part of a real tissue [PDF]
arXiv, 2023 In this study, a computational simulation is employed to place two essential parameters, the permeability of vessels and hydraulic conductivity, under assessment. These parameters impact the movement of drug particles through vessels, and normal and tumoral tissue to examine the concentration of nanoparticles, interstitial pressure, and velocity.
arxiv
Asian Journal of Pharmaceutical Sciences, 2017 The present study was designed to investigate the influence of the pretreatment of piperazine ferulate on pharmacokinetic parameters of methotrexate in methotrexate-induced renal injury rats.
Huiyan Shi +9 more
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Impact of Bosentan in Ameliorating Methotrexate-Induced Tongue Toxicity in Rats [PDF]
المجلة العراقية للصيدلةBackground and objective: Although methotrexate has been utilized over many years, adverse effects are frequent throughout therapy, especially among cancer patients.
Rana Khairi Attarbashee
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Biotechnology Journal, Volume 18, Issue 1, January 2023., 2023 Graphical Abstract and Lay Summary Successful bioprocess modeling starts with experimental planning and accordingly can fail at this early stage. Based on an antibody‐producing CHO fed‐batch process, requirements and pitfalls were investigated, exemplifying their impact on model performance and process characterization.
Benjamin Bayer +3 more
wiley +1 more source
Methotrexate-induced nausea in the treatment of juvenile idiopathic arthritis
Pediatric Rheumatology Online Journal, 2017 Background Methotrexate is the most commonly used disease modifying antirheumatic drug in the treatment of juvenile idiopathic arthritis and can be effective in controlling disease in many patients.
Sonja Falvey +3 more
doaj +1 more source