Results 191 to 200 of about 292,501 (293)

Amide and Thioester Synthesis Via Oxidative Coupling of Alcohols with Amines or Thiols Using Alcohol Dehydrogenases

open access: yesAngewandte Chemie, EarlyView.
Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian   +4 more
wiley   +2 more sources

Insights into organelle forming RNAs: Diversity, functions and future perspectives

open access: yesAnimal Models and Experimental Medicine, EarlyView.
RNA molecules play crucial roles in the formation and maintenance of cellular structures and organelles. These ‘organelle formation RNAs’ include ribosomal RNAs, paraspeckle‐forming RNAs, nuclear speckle‐forming RNAs, nucleolus‐forming RNAs, and cytoskeleton‐forming RNA.
Meng Gong, Xiangting Wang, Xiaolin Liang
wiley   +1 more source

Epigenetic regulation of RNA methylations in gastric cancer. [PDF]

open access: yesOncol Rev
Liu K   +6 more
europepmc   +1 more source

Das Parkinson‐Medikament Tolcapon und dessen Derivative sind Potente Glykomimetische Inhibitoren des Pseudomonas aeruginosa Lektins LecA

open access: yesAngewandte Chemie, EarlyView.
Wir stellen Tolcapon und dessen Derivate als eine neue Klasse potenter Glykomimetika zur Lektininhibition vor. Über 3.200 Verbindungen der Roche‐Substanzbibliothek wurden experimentell gescreent und eine Auswahl biophysikalisch untersucht. Unsere Ergebnisse zeigen das Potenzial zur Entwicklung potenter nicht‐kohlenhydratbasierter glykomimetischer ...
Steffen Leusmann   +8 more
wiley   +1 more source

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