Results 201 to 210 of about 365,379 (338)

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

The emerging roles of METTL1-mediated tRNA m⁷G methylation in cancer development and immunotherapy. [PDF]

Front Immunol
Wang Q, Jiang X, Yuan Y, Li C.
europepmc   +1 more source

O⁶‐Methylguanine‐DNA Methyltransferase (MGMT) as a Determinant of Resistance to Camptothecin Derivatives [PDF]

, 2002
Ryo Okamoto, Hiroshi Takano, Tatsunori Okamura, Ji‐Seon Park, Keiji Tanimoto, Takashi Sekikawa, Wataru Yamamoto, Alex Sparreboom, Jaap Verweij, Masahiko Nishiyama   +9 more
openalex   +1 more source

Psilocybin Production With Genetically Modified Aspergillus nidulans Under Pressurized Conditions

Biotechnology and Bioengineering, EarlyView.
Shake flask cultures of psilocybin‐producing A. nidulans were investigated with respect to nitrogen source, rheology, power input, and oxygen availability, and subsequently scaled to a stirred tank reactor scale based on specific power input to develop and optimize a pressurized bioprocess.
Sophie Weiser, Sidney Jung, Bettina Bardl, Johann E. Kufs, Slavica Janevska, Vito Valiante, Dirk Hoffmeister, Lars Regestein   +7 more
wiley   +1 more source

Prognostic and Therapeutic Potential of Nicotinamide N-Methyltransferase and Hypoxia Inducible Lipid Droplet Associated in Clear Cell Renal Cell Carcinoma. [PDF]

J Korean Med Sci
Kim M, Song G, Joung JY, Seo HK, Lee HH, Chung J.   +5 more
europepmc   +1 more source

Strukturbasiertes Design, Synthese und in vitro Bewertung von Bisubstrat-Inhibitoren der Catechol-0-Methyltransferase (COMT)

, 2003
C. Lerner
openalex   +2 more sources

Mapping molluscan endocrinology: a systematic and critical appraisal

Biological Reviews, EarlyView.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis, Thomas H. Miller, Olwenn V. Martin, Alice Baynes   +3 more
wiley   +1 more source

Design, Synthesis, and Evaluation of Novel Inhibitors of Aminoglycoside-Resistance 16S Ribosomal RNA Methyltransferases. [PDF]

ChemMedChem
Deprez BE, Dey D, Zelinskaya N, Csatary EE, Yang QW, Nie M, Conn GL, Wuest WM.   +7 more
europepmc   +1 more source

Isolated spinach ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit .sup..epsilon. N-methyltransferase and method of inactivating ribulose-1,5-bisphosphatase carboxylase/oxygenase large subunit .sup..epsilon. N-methyltransferase activity

, 2023
Robert L. Houtz
openalex   +1 more source

Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription

, 2020
Zhaona Fan, Lihong He, Mianxiang Li, Ruoyan Cao, Miao Deng, Fan Ping, Xueyi Liang, Yuan He, Tong Wu, Xiaoan Tao, Jian Xu, Bin Cheng, Juan Xia   +12 more
openalex   +1 more source