Results 71 to 80 of about 12,400 (143)

METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway

open access: yesCell Death and Disease
Craniofacial malformations, often associated with syndromes, are prevalent birth defects. Emerging evidence underscores the importance of m6A modifications in various bioprocesses such as stem cell differentiation, tissue development, and tumorigenesis ...
Lan Ma   +10 more
doaj   +1 more source

RNA Binding by the m6A Methyltransferases METTL16 and METTL3

open access: yesBiology
Methyltransferases are a wide-ranging, yet well-conserved, class of molecules that have been found to modify a wide variety of substrates. Interest in RNA methylation has surged in recent years with the identification of the major eukaryotic mRNA m6A methyltransferase METTL3.
openaire   +3 more sources

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