Results 11 to 20 of about 5,468 (165)
Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis
Urinary excretion of mevalonic acid was investigated as an indicator of cholesterol synthesis. In normolipemic volunteers, excretion of mevalonic acid averaged 3.51 +/- 0.59 (SD) micrograms/kg x day1; (n = 24) and was not different from patients with ...
B Lindenthal +5 more
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Effect on callus growth was studied for Citrus grandis cultured with feeding of exogenous mevalonic acid (MVA) at concentrations of 0.04, 0.08, 0.38, 0.77, 1.15 and 1.54 mM.
ZARINA ZAKARIA +2 more
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Inhibition of cholesterol biogenesis by arsenite: preparation of labeled lanosterol*
When mevalonic acid-2-C14 was incubated with rat liver homogenate with the usual cofactors plus 10−3 M arsenite, the formation of labeled cholesterol was inhibited and labeled lanosterol accumulated.
Mary L. Moller, T.T. Tchen
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. Collagen type II (Col II) is among the proposed candidate autoantigens initiaiting rheumatoid arthritis (RA). Statins have been shown to have anti-inflammatory and immunomodulating properties. Mechanisms of statin effects upon the autoantigen-induced T
I. V. Shirinsky, V. S. Shirinsky
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Studies on a mevaldic acid reductase of rat liver*
A TPNH-specific mevaldic reductase of rat liver has been partially purified. This enzyme fraction catalyzes the reduction of both optical isomers of mevaldic acid to isomeric mevalonic acids.
Harold J. Knauss +2 more
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Autoinflammatory disease syndrome of hyperimmunoglobulinemia D
Objective: present a clinical case of a rare autoinflammatory disease. Materials and methods: an analysis of a clinical case of mevalonate kinase deficiency syndrome in an 8-year-old girl was carried out.
T. M. Somova
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Homogenates and subcellular fractions of the intima–media of hog aorta have been prepared and examined for the presence of the enzymes catalyzing the conversion of acetyl CoA to squalene.
Linda L. Slakey +3 more
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Ribonuclease Inhibition of Mevalonic Acid Utilization.
SummaryUtilization of mevalonic acid as determined by incorporation of the 2-C14-labeled compound into non-saponifiable material or into cholesterol or by disappearance of microbiological activity attributable to mevalonic acid in rat liver homogenates was found to be abolished by a preliminary digestion with ribonuclease.
L D, WRIGHT, M, CLELAND, B N, DUTTA
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Incorporation of the following lipid precursors: DL-mevalonic acid-2 3H, 3H palmitic acid and acetic acid-3H sodium salt, into the anther cells of Muscari comosum (L.) Mili. has been investigated.
Barbara Gabara
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SummarySynthetic isovalthine (S-(isopropyl-carboxymethyl)-cysteine) was added to urine from hypercholesterolemic patients that had received mevalonic acid-2-C14 intravenously. Isovalthine recovered from the urine was found to be devoid of radioactivity thus indicating that either (a) mevalonic acid is not a precursor of isovalthine, or (b) mevalonic ...
L D, WRIGHT, W P, HOLLANDER
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