Results 41 to 50 of about 5,468 (165)
Journal of Lipid Research, 1974 Hepatic sterol synthesis is accelerated in animals after a single dose of allylisopropylacetamide, a chemical known to be porphyrogenic. Evidence is provided to show that enhanced sterol biosynthesis is due to an increased formation of mevalonic acid ...
Luigi Taddeini +2 more
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Enhanced Metabolite Productivity of Escherichia coli Adapted to Glucose M9 Minimal Medium
Frontiers in Bioengineering and Biotechnology, 2018 High productivity of biotechnological strains is important to industrial fermentation processes and can be constrained by precursor availability and substrate uptake rate.
Peter Rugbjerg +3 more
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Вопросы современной педиатрии, 2012 Periodic fever syndrome with mevalonate kinase deficiency, also known as hyperimmunoglobulinemia D syndrome, is characterized by early onset and relatively benign course.
Yu. S. Patrusheva, M. D. Bakradze
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Highly sensitive assay of HMG-CoA reductase activity by LC-ESI-MS/MS
Journal of Lipid Research, 2007 We have developed a new sensitive and specific nonradioisotope assay method to measure the activity of HMG-CoA reductase, the rate-controlling enzyme in the cholesterol biosynthetic pathway.
Honda Akira +5 more
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Production of plasma esterified cholesterol in lean, normotriglyceridemic humans
Journal of Lipid Research, 1974 The rate of production of plasma esterified cholesterol was measured both in vivo and in vitro in seven subjects and in vivo alone in eight subjects. All subjects were lean, clinically healthy, and had triglyceride concentrations < 1.5 μmoles/ml. In vivo
Philip J. Barter
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Molecular Characterization of Trypanosoma evansi Mevalonate Kinase (TeMVK)
Frontiers in Cellular and Infection Microbiology, 2018 The mevalonate pathway is an essential part of isoprenoid biosynthesis leading to production of a diverse class of >30,000 biomolecules including cholesterol, heme, and all steroid hormones.
Daniel P. Duarte +8 more
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Metabolic engineering of Escherichia coli for the utilization of ethanol
Journal of Biological Research - Thessaloniki, 2020 Background The fuel ethanol industry has made tremendous progress in the last decades. Ethanol can be obtained by fermentation using a variety of biomass materials as the feedstocks.
Yujin Cao +7 more
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CHEMICAL INDEXES CALCULATED FOR 8,11,13-TRIENABIETANE DITERPENOIDS ISOLATED FROM SWARTZIA SPECIES
Eclética Química, 2018 The disparity found in the molecular structures of compounds isolated from nine plants of the Swartzia genus indicates that the Swartzia species that furnished cassane diterpenoids and triterpenoidal saponins are more recent, since these metabolites have
Aderbal Farias Magalhães +3 more
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Prolonged inhibition of cholesterol synthesis explains the efficacy of atorvastatin
Journal of Lipid Research, 1997 HMG-CoA reductase inhibitors or statins are effective in both the primary and secondary prevention of coronary heart disease, the extent of benefit being proportional to the reduction in low density lipoprotein (LDL) cholesterol achieved. Atorvastatin, a
R P Naoumova +7 more
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Chemistry of mevalonic acid [PDF]
Biochemical Journal, 1969 J W, Cornforth, R H, Cornforth
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