Results 111 to 120 of about 1,176 (169)

Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function

Nature Communications, 2019
MG53 is a protein that regulates the cell membrane repair process, and it’s been suggested that it might play a role in diabetes. Here, the authors demonstrate that circulating MG53 functions as a myokine to facilitate tissue injury-repair and ...
Zehua Bian, Qiang Wang, Xinyu Zhou, Tao Tan, Ki Ho Park, H. Fritz Kramer, Alan McDougal, Nicholas J. Laping, Sanjay Kumar, T. M. Ayodele Adesanya, Matthew Sermersheim, Frank Yi, Xinxin Wang, Junwei Wu, Kristyn Gumpper, Qiwei Jiang, Duofen He, Pei-Hui Lin, Haichang Li, Fangxia Guan, Jingsong Zhou, Mark J. Kohr, Chunyu Zeng, Hua Zhu, Jianjie Ma   +24 more
doaj   +1 more source

MG53 mitigates warm ischemic lung injury in a murine model of transplantation. [PDF]

J Thorac Cardiovasc Surg
Lung transplant warm ischemia-reperfusion injury (IRI) results in cellular injury, inflammation, and poor graft function. Mitsugumin 53 (MG53) is an endogenous protein with cell membrane repair properties and the ability to modulate the inflammasome. We hypothesize that the absence of circulating MG53 protein in the recipient increases IRI, and higher ...
Gouchoe DA, Yi T, Kim JL, Lee YG, Black SM, Breuer C, Ma J, Whitson BA.   +7 more
europepmc   +3 more sources

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Mitochondrial dysfunction induced by mAb10F5 is attenuated by co-treatment with MG53 [PDF]

, 2018
Access to thesis permanently restricted to Ball State community only.PURPOSE: Rheumatic heart disease (RHD) is an autoimmune disorder triggered by prolonged Streptococcus pyogenes infections.
Eviston, Deavin Michael
core  

PO-249 Does High Serum MG53 Level Associates with Better Cardiorespiratory Function? There is no full text article associated whit this abstract [PDF]

, 2018
Objective To investigate the association between the endogenous human serum MG53 level and cardio-respiratory function in response to graded exercise test (GXT).
Ren, Yingbin, Shao, Jing, Zhou, Lili, Liu, Naixi, Han, Qi, Muqing, Yi, Xu, Baohua   +6 more
core   +1 more source

OR-010 The potential role of MG53 in exercise-mediated modulation of diabetic cardiomyopathy in db/db mice: There is no full paper associated with this abstract [PDF]

, 2018
Objective Diabetic cardiomyopathy is a major complication of Type 2 diabetes. Recent studies have shown that as an E3 ligase targeting insulin receptor (IR) and insulin receptor substrate 1 (IRS1), MG53 could result in insulin resistance and metabolic ...
Zhang, Yi, Ding, Shuzhe, Sun, Yi
core   +1 more source

PO-063 Exercise alleviates insulin resistance by regulating MG53 and IR/IRS/AKT/mTOR signaling in db/db mice skeletal muscle: There is no full text article associated with this abstract [PDF]

, 2018
Objective In the current study, we aim to investigate whether 12-week treadmill exercise alleviates insulin resistance and muscle atrophy, and to explore whether MG53 along with IR/IRS/AKT/mTOR cascade play a role in the physiopathological changes of db ...
Zhang, Yi, Ding, Shuzhe, Sun, Yi
core   +1 more source

MG53 in Early Skeletal Muscle Stem Cell Activation: Implications for Aged Muscle Regeneration. [PDF]

Cells
Xu Y, Zih-Shuo JW, Zhang Z, Chen P, Alizai U, Sathish K, Lilian S, Yan Z, Whitson BA, Pawlik TM, Zhu H.   +10 more
europepmc   +1 more source

Tripartite motif-containing 72 (TRIM72; MG53) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Aldh3a1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to amyotrophic lateral sclerosis progression. [PDF]

Free Radic Biol Med
Li A, Dong L, Li X, Yi J, Wu JY, Ma J, Zhou J.   +6 more
europepmc   +1 more source