Results 81 to 90 of about 1,176 (169)

TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu, Ling‐Jung Yen, Hui‐Ling Hsia, Zi‐Xeng Weng, Chi‐Hsiang Chung, Paul Wei‐Che Hsu, Chih‐Wei Chiu, Wu‐Chien Chien, Tsung‐Hsien Chang   +8 more
wiley   +1 more source

HFD treatment induces MG53 localization to the plasma membrane and mitochondria in skeletal muscle. [PDF]

, 2015
(A) IHC staining of longitudinal sections of skeletal muscle reveals striated patterns of MG53 in ND-treated mice (left). HFD treatment results in the aggregation of MG53 near the plasma membrane (middle).
Yuqi Cui (736228), Ki Ho Park (342977), Bo Zhang (6559), T. M. Ayodele Adesanya (736230), Xuefeng Zhou (28696), Hua Zhu (131619), Hanley Ma (736226), Frank Yi (494218), Zehua Bian (736227), Tao Tan (204136), Jason Liu (193360), Xinyu Zhou (736229), Zhishui Chen (736231)   +12 more
core   +1 more source

Development of an Ophthalmic Hydrogel to Deliver MG53 and Promote Corneal Wound Healing. [PDF]

Pharmaceutics
Background/Objective: A clinical need exists for more effective therapeutics and sustained drug delivery systems to promote ocular surface healing. This study tested the hypothesis that a novel biodegradable, thermoresponsive hydrogel loaded with the human recombinant (rh)MG53 protein, which we have demonstrated to promote corneal healing without ...
Chandler HL, Moradi S, Green SW, Chen P, Madden C, Zhang L, Zhang Z, Park KH, Ma J, Zhu H, Swindle-Reilly KE.   +10 more
europepmc   +4 more sources

CELLULAR AND MOLECULAR MECHANISMS OF MUSCLE REGENERATION

Khyber Medical University Journal, 2021
BACKGROUND: Muscle injuries are a common manifestation of exercise and non-mechanical factors such as drugs, genetic defects, and systemic diseases. Despite their clinical importance, the cellular and molecular mechanisms of muscle injury and repair are ...
Rizwan Qaisar
doaj   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

PROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling, Dounia Bouragba, Elisa Negroni, Capucine Trollet, Margit Zweyer, Dieter Swandulla, Kay Ohlendieck   +6 more
wiley   +1 more source

Mitsugumin 53 protects the kidney from severe burn injury in mice

Burns & Trauma, 2013
Mitsugumin 53 (MG53), a newly identified muscle-specific protein, is an essential component of the cell membrane repair machinery in skeletal and cardiac muscle. However, the role of MG53 after burns in other tissues remains unclear.
Yanjun Wu, Jian Huang, Daisong Liu, Jianglin Tan, Yanmeng Peng, Junjie Yang, Yanyan Cui , Weifeng He, Gaoxing Luo, Jun Wu   +9 more
doaj   +1 more source

Exogenous MG53 Protects Adult Mouse Cardiomyocytes by Preventing Mitochondrial Damage in Response to Oxidative Stress [PDF]

, 2019
Ischemic heart disease is a major cause of mortality and morbidity world-wide and its incidence is continually increasing as other health factors, such as diabetes type II and obesity, climb.
Kristyn Gumpper (1317063), Ki Ho Park (342977), Renzhi Han (276195), Pei-Hui Lin (556722), Jianjie Ma (342983), Xinyu Zhou (736229)   +5 more
core   +1 more source

Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53 [PDF]

, 2021
As a master regulator of metabolism, AMP-activated protein kinase (AMPK) is activated upon energy and glucose shortage but suppressed upon overnutrition.
Yang, D, Lejiao Ren, Lv, F, Quan, L, Xiuqin Zhang, Ren, L, Xiaoyu Bai, Fengli Xu, Xu, F, Fengxiang Lv, Zhong Yu, Rui-Ping Xiao, Peng, W, Bai, X, Dan Yang, Li Zhi, Wang, X, Wei Peng, Zhi, L, Jiang, P, Kunlun Cheng, Zhang, Y, Zhang, X, Xianhua Wang, Cheng, K, Yu, Z, Yan Zhang, Li Quan, Hu, X, Peng Jiang, Xiao, RP, Xinli Hu   +31 more
core   +1 more source

Diversity and Antifungal Susceptibility of Malassezia spp. Isolated From Brazilian Patients With Pityriasis Versicolor and Seborrheic Dermatitis

Mycoses, Volume 69, Issue 4, April 2026.
ABSTRACT Background Malassezia spp. are part of the microbiota of many animals, including humans. However, under certain conditions, they can become pathogenic. Diseases associated with Malassezia include pityriasis versicolor (PV), seborrheic dermatitis (SD), Malassezia folliculitis, atopic dermatitis, psoriasis and fungemia.
Diogo Coelho de Pádua Oliveira, Ana Paula Possa, Ana Raquel de Oliveira Santos, Ana Kleiber P. Borges, Patrícia Silva Cisalpino, Raquel Vilela, Carlos Augusto Rosa, Susana Johann   +7 more
wiley   +1 more source

MG53 permeates through blood-brain barrier to protect ischemic brain injury [PDF]

, 2016
Ischemic injury to neurons represents the underlying cause of stroke to the brain. Our previous studies identified MG53 as an essential component of the cell membrane repair machinery.
Li, Yu, Lin, Peihui, Wang, Zhen, Nianqiao Gong, Jingsong Zhou, Han, Yu, Jing Zeng, Peihui Lin, Zhu, Hua, Yu Han, Ki Ho Park, Zhen Wang, He, Duofen, Bian, Zehua, Hua Zhu, Duofen He, Zhang, Bo, Ma, Jianjie, Yu Li, Zhou, Jingsong, Xinquan Wang, Yao, Yonggang, Park, Kiho, Tao Tan, Yonggang Yao, Zeng, Jing, Yukai Liu, Xinyu Zhou, Zehua Bian, Meng Zhang, Chen, Zhishui, Haichang Li, Li, Haichang, Gong, Nianqiao, Wang, Xinquan, Zeng, Chunyu, Chunyu Zeng, Zhishui Chen, Bo Zhang, Zhou, Xinyu, Jianjie Ma, Liu, Yukai, Chen, Ken, Zhang, Meng, Tan, Tao, Ken Chen   +45 more
core   +2 more sources