Additional file 2 of MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer [PDF]
, 2021 Additional file 2: Supplementary Figure S2. Knockout of MG53 results in elevated stress granule formation in mg53-/- lung. (A) The whole protein extracts from wild type and mg53-/- lung were subjected to western blot analysis with anti-MG53 and G3BP2 ...
Jianjie Ma (11434236) +16 more
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Searching for MG53-Interacting Proteins in Skeletal Muscle [PDF]
Biophysical Journal, 2012 Mitsugumin 53 (MG53, a muscle-specific tripartite motif family protein) contributes to cell membrane repair in skeletal muscle by facilitating vesicle trafficking. To examine possible involvement of MG53 in skeletal excitation-contraction coupling, GST-fused MG53 proteins purified using GST pull-down assay were incubated with solubilized triad ...
Jin Lee, Keon +2 more
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Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy [PDF]
, 2012 Mitsugumin 53 (MG53), a muscle-specific TRIM family protein, is an essential component of the cell membrane repair machinery. Here, we examined the translational value of targeting MG53 function in tissue repair and regenerative medicine. Although native
Hwang, Moonsun +19 more
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Comparison of main characteristics in DM and control groups (MG53<8.57 pg/ml excluded). [PDF]
, 2023 Comparison of main characteristics in DM and control groups ...
Mine Okur (15355282) +8 more
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Sustained delivery of rhMG53 promotes diabetic wound healing and hair follicle development
Bioactive Materials, 2022 MG53 is an essential component of the cell membrane repair machinery, participating in the healing of dermal wounds. Here we develop a novel delivery system using recombinant human MG53 (rhMG53) protein and a reactive oxygen species (ROS)-scavenging gel ...
Hong Niu +12 more
doaj +1 more source
Distribution of MG53 levels in various groups (<8.57 pg/ml excluded). [PDF]
, 2023 Distribution of MG53 levels in various groups (
Mine Okur (15355282) +8 more
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MG53 inhibits cellular proliferation and tumor progression in colorectal carcinoma
International Journal of Biological Sciences, 2022 Cancer is the second leading cause of mortality after cardiovascular diseases in the United States. Chemotherapy is widely used to treat cancers. Since the development of drug resistance is a major contributor towards the failure of chemotherapeutic regimens, efforts have been made to develop novel inhibitors that can combat drug resistance and ...
Gupta, Pranav +9 more
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Redox-dependent oligomerization through a leucine zipper motif is essential for MG53-mediated cell membrane repair [PDF]
, 2011 We recently discovered that MG53, a muscle-specific tripartite motif (TRIM) family protein, functions as a sensor of oxidation to nucleate the assembly of cell membrane repair machinery.
Jae-kyun Ko +4 more
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MG53 does not mark cardiovascular risk and all-cause mortality in subjects with type 2 diabetes: A prospective, observational study [PDF]
, 2023 Aims: Subjects with type 2 diabetes (T2D) are characterized by a high cardiovascular morbidity and mortality. MG53, a marker of peripheral insulin resistance, has been linked with impaired 13-cell function and decreased 13-cell survival, and its ...
Francesco Raggi +11 more
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MG53 inhibits angiogenesis through regulating focal adhesion kinase signalling [PDF]
Journal of Cellular and Molecular Medicine, 2021 AbstractMitsugumin 53 (MG53), which is expressed predominantly in striated muscle, has been demonstrated to be a myokine/cardiokine secreted from striated muscle under specific conditions. The important roles of MG53 in non‐striated muscle tissues have also been examined in multiple disease models.
Jinling Dong +9 more
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