Results 11 to 20 of about 7,499 (206)
MICB Allele Genotyping on Microarrays by Improving the Specificity of Extension Primers. [PDF]
PLoS ONE, 2015 Major histocompatibility complex (MHC) class I chain-related gene B (MICB) encodes a ligand for activating NKG2D that expressed in natural killer cells, γδ T cells, and αβ CD8+ T cells, which is associated with autoimmune diseases, cancer, and infectious
In-Cheol Baek +3 more
doaj +6 more sources
Genetic variants of MICB and PLCE1 and associations with non-severe dengue. [PDF]
PLoS ONE, 2013 BackgroundA recent genome-wide association study (GWAS) identified susceptibility loci for dengue shock syndrome (DSS) at MICB rs3132468 and PLCE1 rs3740360.
James Whitehorn +12 more
doaj +7 more sources
Stress-induced MICA and MICB molecules in oncology [PDF]
Медицинская иммунология, 2022 MICA and MICB molecules, MHC class I chain-related proteins, are expressed on the membranes of damaged, transformed or infected cells. These glycoproteins bind to the NKG2D receptor of NK cells, resulting in their activation and cytotoxic response ...
S. A. Yurevna +2 more
doaj +3 more sources
Diagnostics, 2023 Dengue is an arboviral disease that has spread globally and become a major public health concern. A small proportion of patients may progress from symptomatic dengue fever (DF) to dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS).
Imaniar Noor Faridah +7 more
doaj +2 more sources
Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands. [PDF]
PLoS Pathogens, 2010 The activating immunoreceptor NKG2D promotes elimination of infected or malignant cells by cytotoxic lymphocytes through engagement of stress-induced MHC class I-related ligands.
Steffen Müller +3 more
doaj +2 more sources
Circulating levels of soluble MICB in infants with symptomatic primary dengue virus infections. [PDF]
PLoS ONE, 2014 Dengue is the most prevalent arthropod-borne viral illness in humans. A MHC class I polypeptide-related sequence B (MICB) single nucleotide polymorphism (SNP) was previously associated with symptomatic dengue compared to non-dengue causes of acute ...
Daniel H Libraty +4 more
doaj +2 more sources
Journal of Immunology Research, 2016 Objectives. The variant rs3828903 within MICB, a nonclassical MHC class I chain-related gene, was detected to contribute to systemic lupus erythematosus (SLE) in a Caucasian population.
Yue-miao Zhang +6 more
doaj +2 more sources
Genetic variants of MICB and PLCE1 and associations with the laboratory features of dengue [PDF]
BMC Infectious Diseases, 2017 Background A previous genome-wide association study identified 2 susceptibility loci for severe dengue at MICB rs3132468 and PLCE1 rs3740360 and further work showed these mutations to be also associated with less severe clinical presentations. The aim of
James Whitehorn +10 more
doaj +5 more sources
Causal associations of MICB, CTSA, and MMP9 proteins with oral cancer: Mendelian randomization study
Scientific ReportsOral cancer (ORCA) is the most prevalent histological subtype of oral malignancies in which immune modulation is relevant. The goal of this work was to employ Mendelian randomization (MR) to investigate the causal connection between the immune-related ...
Bowen Dong +7 more
doaj +2 more sources
A Novel MICB-Targeting CAR-NK Cells for the Treatment of Pancreatic Cancer. [PDF]
Int J Mol SciMICB-targeting CAR-NK (chimeric antigen receptor-modified natural killer cells) therapy may serve as off-the-shelf immunotherapy. We designed soluble Anti-MICB-scFv blocks tumor immune evasion targeting the MICB antigen, thereby enhancing CAR-NK ...
Jin W +5 more
europepmc +2 more sources