Results 31 to 40 of about 7,499 (206)

Integrative Population Analysis of MICA and MICB Using Unsupervised Machine Learning in a Large Histocompatibility Laboratory Cohort

J
Background: Non-classical MHC class I molecules MICA and MICB are stress-inducible NKG2D ligands that contribute to immune surveillance, non-HLA antibody formation, and alloreactivity in solid organ and hematopoietic stem cell transplantation; population-
Luis Ramalhete, Paula Almeida, Ruben Araújo, Eduardo Espada   +3 more
doaj   +1 more source

MHC class I-related chain A and B ligands are differentially expressed in human cervical cancer cell lines

Cancer Cell International, 2011
Background Natural killer (NK) cells are an important resource of the innate immune system directly involved in the spontaneous recognition and lysis of virus-infected and tumor cells.
Bravo-Cuellar Alejandro, Hernandez-Flores Georgina, Ortiz-Lazareno Pablo, del Toro-Arreola Alicia, Gonzalez-Ramella Oscar, Barros-Nuñez Patricio, Haramati Jesse, Jimenez-Perez Miriam, Cid-Arregui Angel, Aguilar-Lemarroy Adriana, Arreygue-Garcia Naela, del Toro-Arreola Susana, Daneri-Navarro Adrian, Jave-Suarez Luis F   +13 more
doaj   +1 more source

MICB alleles by ASPE on microarrays and PCR-SBT and MICB population allele frequency (Korean population) to compare them with the test sample frequency.

, 2015
¶Determination in MICB exon 6.MICB alleles by ASPE on microarrays and PCR-SBT and MICB population allele frequency (Korean population) to compare them with the test sample frequency.
Tai-Gyu Kim (594599), In-Cheol Baek (692741), Jung-Pil Jang (692740), Eun-Jeong Choi (389699)   +3 more
core   +1 more source

Results of the IVW Mendelian randomization analysis of the effects of MICB and CD209 plasma levels on VVs.

, 2022
Results of the IVW Mendelian randomization analysis of the effects of MICB and CD209 plasma levels on VVs.
Hakon Hakonarson (102913), Bahram Namjou (272325), Ian B. Stanaway (12570436), Wei-Qi Wei (4232797), Yakov A. Tsepilov (8363700), Gail P. Jarvik (8636064), Pradeep Suri (5797202), Joe Glessner (12575264), Alexandra S. Shadrina (5572979), Elizaveta E. Elgaeva (8818136)   +9 more
core   +1 more source

Association study of MICA and MICB in Alzheimer’s disease

Tissue Antigens, 2009
AbstractFollowing the replication of the association of the human leucocyte antigen (HLA) allele, HLA‐B*07, with Alzheimer’s disease (AD) in the cohort of the Oxford Project to Investigate Memory and Ageing (OPTIMA) in a previous study, we examined whether that association could be due to linkage disequilibrium with MICA or MICB alleles.
Quiroga, I, Lehmann, D, Barnardo, M, Fuggle, S, Cortina-Borja, M, Warden, DR, Smith, A   +6 more
openaire   +2 more sources

ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells

Molecular Medicine Reports, 2013
The aim of this study was to investigate the role of ADAM15 in MHC class I polypeptide-related sequence B (MICB) protein ectodomain shedding and observe whether or not gemcitabine affects MICB shedding from PANC-1 cells. In this study, immunohistochemistry of MICB and ADAM15 were performed on tumor samples obtained
Xiaohui, Duan, Xianhai, Mao, Weijia, Sun
openaire   +3 more sources

SNP-Density Crossover Maps of Polymorphic Transposable Elements and HLA Genes Within MHC Class I Haplotype Blocks and Junction

Frontiers in Genetics, 2021
The genomic region (~4 Mb) of the human major histocompatibility complex (MHC) on chromosome 6p21 is a prime model for the study and understanding of conserved polymorphic sequences (CPSs) and structural diversity of ancestral haplotypes (AHs)/conserved ...
Jerzy K. Kulski, Jerzy K. Kulski, Shingo Suzuki, Takashi Shiina   +3 more
doaj   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

MICB~HLA-B

, 2013
The data we have uploaded includes the MICB genotypes and the HLA-B genotypes of 400 unrelated healthy Han individuals from Zhejiang province ...
Zhedong Han (3251244), Nanying Chen (3251241), Ji He (40669), Wang, Wei, Faming Zhu (3251253), Wei Zhang (405), Tao, Sudan, Zhang, Wei, Junjun He (521491), Sudan Tao (3251238), Yanling Ying (3251247), Ying, Yanling, Han, Zhedong, Hangjun Lv (381695), He, Ji, Zhu, Faming, He, Yanmin, Yanmin He (3251250), Chen, Nanying, Wei Wang (17594), He, Junjun, Lv, Hangjun   +21 more
core   +1 more source

Major histocompatibility complex class I Chain-related A and B (MICA and MICB) gene, allele, and haplotype associations with dengue infections in ethnic thais

, 2020
Background. Major histocompatibility complex class I chain-related (MIC) A and B (MICA and MICB) are polymorphic stress molecules recognized by natural killer cells. This study was performed to analyze MIC gene profiles in hospitalized Thai children with
Srikiatkhachorn, Anon, Fernandez, Stefan, Macareo, Louis R., Collins, Robert W.M., Jarman, Richard G., Stephens, Henry A.F., Rothman, Alan L., Vejbaesya, Sasijit, Kalayanarooj, Siripen, Luangtrakool, Komon, Cox, Steven T., Luangtrakool, Panpimon, Apisawes, Kusuma, Ngamhawornwong, Somporn   +13 more
core   +1 more source