Results 51 to 60 of about 7,499 (206)
Bacterial biofilms play an important role in urinary tract infections (UTIs), being responsible for persistent infections that lead to recurrences and relapses.
Katheryne Benini Martins +6 more
doaj +1 more source
T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li +11 more
wiley +1 more source
MUC1-C is a master regulator of MICA/B NKG2D ligand and exosome secretion in human cancer cells
Background The MUC1-C protein evolved in mammals to protect barrier tissues from loss of homeostasis; however, MUC1-C promotes oncogenesis in association with chronic inflammation. Aberrant expression of MUC1-C in cancers has been linked to depletion and
Satoshi Ishikawa +13 more
doaj +1 more source
Overview on Epstein–Barr Virus–Host Interactions With a Focus on Host Cell Transcriptome Alterations
ABSTRACT The Epstein–Barr virus (EBV) belongs to the gamma subgroup of human herpesviruses. EBV is particularly lymphotropic regarding its latency, meaning that it preferentially targets lymphocytes as its immunological niche. During the establishment of the complex virus–host relationships, the virus influences the human host cell transcriptome ...
Louise Wallot +5 more
wiley +1 more source
Multiple sclerosis (MS) is an autoimmune multifactorial degenerative disease with detrimental affliction on central nervous system. MHC class I chain- related geneA,B(MICA and MICB) are nonclassical human leukocyte antigens that can affect on ...
Saeid Abediankenari +8 more
doaj
Differential secretion mechanisms and predicted structural flexibility are described as additional effects of MICA polymorphism in the immune response. Structural features might explain impaired antibody recognition of certain MICA alleles, supporting that MICA genotyping should be considered in biomarker studies and NKG2D‐based therapeutic development.
Silvia López‐Borrego +5 more
wiley +1 more source
The percentage of epithelial cells expressing MICA/MICB is increased with COPD severity.
Human lung tissue was dispersed and stained with monoclonal antibodies against CD45, CD56, NKG2D, CD326, and MICA/MICB. (A) Representative staining showing the expression of NKG2D on CD45+ CD56+ cells from a smoker without COPD (left panel) and a subject
Sean Crudgington (560846) +9 more
core +1 more source
Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du +9 more
wiley +1 more source
Difference in influence of commercial industrial paints on microbial biofilms and planktonic cells [PDF]
This study compares the effect of commercial industrial paints on the Escherichia coli PMFKG-F2, Proteus mirabilis PMFKG-F4 and Saccharomyces cerevisiae PMFKG-F6 planktonic cells and biofilms.
Grujić Sandra M. +4 more
doaj +1 more source
5′-UTR and 3′-UTR Regulation of MICB Expression in Human Cancer Cells by Novel microRNAs
The treatment of cancer through the induction of natural killer group 2, member D (NKG2D) ligands is of interest, but understanding of mechanisms controlling expression of individual ligand is limited.
Banchob Sripa +4 more
core +1 more source

