Results 61 to 70 of about 7,499 (206)

Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. [PDF]

open access: yes, 2011
Hypovolemic shock (dengue shock syndrome (DSS)) is the most common life-threatening complication of dengue. We conducted a genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam.
Tuan, NM   +109 more
core   +1 more source

SAHA modulates MICA and ULBPs expression on JEG-3 cells and enhances their susceptibility to NK cell-mediated cytotoxicity

open access: yesМедицинская иммунология
Pregnancy is characterized by the emergence of a unique immunotolerant microenvironment that supports fetal development. Trophoblast cells and natural killer (NK) cells cooperate to establish the microenvironment essential for successful embryo ...
E. V. Tyshchuk   +4 more
doaj   +1 more source

Decitabine Enhances Vγ9Vδ2 T Cell-Mediated Cytotoxic Effects on Osteosarcoma Cells via the NKG2DL–NKG2D Axis

open access: yesFrontiers in Immunology, 2018
γδ T cell-based immunotherapy for osteosarcoma (OS) has shown limited success thus far. DNA-demethylating agents not only induce tumor cell death but also have an immunomodulatory function.
Zhan Wang   +10 more
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo   +6 more
wiley   +1 more source

Antibacterial Effect of the In Vitro Interaction Between Clotrimazole and Chlorhexidine Against Staphylococcus pseudintermedius With Known Resistance Patterns Isolated From Canine Pyoderma

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The 2:1 chlorhexidine–clotrimazole combination demonstrated enhanced antibacterial activity against canine Staphylococcus pseudintermedius isolates, including resistant strains. Reduced MIC values, predominantly additive interactions and absence of antagonism support its use as a promising topical strategy for canine pyoderma management.
Brenda Gallegos‐Torres   +3 more
wiley   +1 more source

Expression of MHC class I-related Chain B (MICB) molecules on renal transplant biopsies.

open access: yes, 2006
BACKGROUND: MICA and MICB (MHC class I-related chain A and B) are polymorphic genes that encode molecules related to MHC class I and are expressed on epithelial cells in response to stress.
Susan V. Fuggle   +6 more
core   +1 more source

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

open access: yesThe FEBS Journal, Volume 293, Issue 17, Page 5121-5139, September 2026.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture   +3 more
wiley   +1 more source

MICA and MICB Gene Identification Method

open access: yes, 2021
Bakalářská práce se zabývá identifikací alel MICA a MICB genů pro následné použití v rámci transplantce kostní dřeně. Cílem práce je seznámení se s významem genů MICA a MICB, porovnání sekvenačních metod, zejména Sangerovo sekvenování a Next-generation ...
Rottenbornová, Lucie
core  

Ferroptosis‐Based Peripheral Immune Dysregulation and Diagnostic Signatures in Parkinson's Disease: An RNA Transcriptomic and Single‐Cell Immune Sequencing Analysis

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
This study explored the crosstalk between ferroptosis‐related genes and peripheral immune alterations in Parkinson's disease. We constructed a gene signature and classified molecular subtypes, and further pinpointed key ferroptosis‐associated molecules in immune cells and neuronal cells.
Lei Cheng   +5 more
wiley   +1 more source

Expression analysis of MICA and MICB by real-time quantitative PCR in Sjögren's syndrome accessory salivary glands.

open access: yes, 2013
Relative expression level of MICA (A) and MICB (B) in Sjögren's syndrome patients as compared to healthy controls. The differences between patients and controls are not significant as assessed by Mann-Whitney U test (α = 0.27 for MICA and α = 0.53 for ...
Marc Ardizzone (30812)   +4 more
core   +1 more source

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