Results 61 to 70 of about 7,499 (206)
Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. [PDF]
Hypovolemic shock (dengue shock syndrome (DSS)) is the most common life-threatening complication of dengue. We conducted a genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam.
Tuan, NM +109 more
core +1 more source
Pregnancy is characterized by the emergence of a unique immunotolerant microenvironment that supports fetal development. Trophoblast cells and natural killer (NK) cells cooperate to establish the microenvironment essential for successful embryo ...
E. V. Tyshchuk +4 more
doaj +1 more source
γδ T cell-based immunotherapy for osteosarcoma (OS) has shown limited success thus far. DNA-demethylating agents not only induce tumor cell death but also have an immunomodulatory function.
Zhan Wang +10 more
doaj +1 more source
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo +6 more
wiley +1 more source
The 2:1 chlorhexidine–clotrimazole combination demonstrated enhanced antibacterial activity against canine Staphylococcus pseudintermedius isolates, including resistant strains. Reduced MIC values, predominantly additive interactions and absence of antagonism support its use as a promising topical strategy for canine pyoderma management.
Brenda Gallegos‐Torres +3 more
wiley +1 more source
Expression of MHC class I-related Chain B (MICB) molecules on renal transplant biopsies.
BACKGROUND: MICA and MICB (MHC class I-related chain A and B) are polymorphic genes that encode molecules related to MHC class I and are expressed on epithelial cells in response to stress.
Susan V. Fuggle +6 more
core +1 more source
Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture +3 more
wiley +1 more source
MICA and MICB Gene Identification Method
Bakalářská práce se zabývá identifikací alel MICA a MICB genů pro následné použití v rámci transplantce kostní dřeně. Cílem práce je seznámení se s významem genů MICA a MICB, porovnání sekvenačních metod, zejména Sangerovo sekvenování a Next-generation ...
Rottenbornová, Lucie
core
This study explored the crosstalk between ferroptosis‐related genes and peripheral immune alterations in Parkinson's disease. We constructed a gene signature and classified molecular subtypes, and further pinpointed key ferroptosis‐associated molecules in immune cells and neuronal cells.
Lei Cheng +5 more
wiley +1 more source
Relative expression level of MICA (A) and MICB (B) in Sjögren's syndrome patients as compared to healthy controls. The differences between patients and controls are not significant as assessed by Mann-Whitney U test (α = 0.27 for MICA and α = 0.53 for ...
Marc Ardizzone (30812) +4 more
core +1 more source

