Results 221 to 230 of about 1,644,764 (242)

[Progress in gene knockout mice].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2019
The establishment and development of gene knockout mice have provided powerful support for the study of gene function and the treatment of human diseases. Gene targeting and gene trap are two techniques for generating gene knockout mice from embryonic stem cells. Gene targeting replaces endogenous knockout gene by homologous recombination.
Chaoxuan Wang, Hang Sun
openaire   +2 more sources

Knockout Mice

New England Journal of Medicine, 1996
J A, Majzoub, L J, Muglia
openaire   +2 more sources

P.2.b.019 Behavioural characterization of mice knockout for the nociceptin/orphanin FQ receptor gene in animal models of anxiety

European Neuropsychopharmacology, 2006
E. Gavioli, G. Marzola, G. Calo’
semanticscholar   +1 more source

Generation of knockout mice by Cpf1-mediated gene targeting

Nature Biotechnology, 2016
Yongsub Kim, Seung-A. Cheong, Jong Geol Lee, Sang-Wook Lee, Myeong Sup Lee, In-Jeoung Baek, Y. Sung   +6 more
semanticscholar   +1 more source

IL-4 Knockout Mice

2003
The pleiotropic cytokine interleukin-4 is a major regulator of the immune system. It has a multitude of biological effects, and participates in protective as well as in pathological responses. IL-4 can affect a variety of cells in multiple ways by regulating antibody production, hematopoiesis, the development of effector T-helper cell responses, and ...
Ingrid Müller, Pascale Kropf
openaire   +2 more sources

Conditional Knockout Mice

2003
Frieder Schwenk, Ralf Kühn
openaire   +3 more sources

Preparation of Knockout Mice

2003
Nobuyo Maeda, Jesús Osada
openaire   +3 more sources

GenPharm's Knockout Mice

Science, 1992
Robert M. Kay, Jonathan J. Macquitty
openaire   +2 more sources

Utility of Oatp1a/1b-Knockout and OATP1B1/3-Humanized Mice in the Study of OATP-Mediated Pharmacokinetics and Tissue Distribution: Case Studies with Pravastatin, Atorvastatin, Simvastatin, and Carboxydichlorofluorescein

Drug Metabolism And Disposition, 2014
J. W. Higgins, Jing Q. Bao, A. Ke, J. Manro, J. K. Fallon, Philip C. Smith, M. Zamek-Gliszczynski   +6 more
semanticscholar   +1 more source

Knockout Mice in Inflammation Research

2001
The study of mutations has tremendously aided the identification of genes and their functions in many different experimental organisms. In the past, researchers working in mammalian systems relied on naturally occurring mutations or those induced by chemicals or radiation to study the different biological roles of a gene.
openaire   +2 more sources