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2003
The pleiotropic cytokine interleukin-4 is a major regulator of the immune system. It has a multitude of biological effects, and participates in protective as well as in pathological responses. IL-4 can affect a variety of cells in multiple ways by regulating antibody production, hematopoiesis, the development of effector T-helper cell responses, and ...
Ingrid Müller, Pascale Kropf
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The pleiotropic cytokine interleukin-4 is a major regulator of the immune system. It has a multitude of biological effects, and participates in protective as well as in pathological responses. IL-4 can affect a variety of cells in multiple ways by regulating antibody production, hematopoiesis, the development of effector T-helper cell responses, and ...
Ingrid Müller, Pascale Kropf
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Knockout Mice in Inflammation Research
2001The study of mutations has tremendously aided the identification of genes and their functions in many different experimental organisms. In the past, researchers working in mammalian systems relied on naturally occurring mutations or those induced by chemicals or radiation to study the different biological roles of a gene.
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Generation of brevican knockout mice
Academic Journal of Second Military Medical University, 2011Xi Han, Yan Dong
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