Results 71 to 80 of about 1,004,074 (357)

Synthesis and Diversification of Chiral Spirooxindoles via Organocatalytic Cascade Reactions

open access: yesChemistry Proceedings, 2023
The synthesis of chiral spirooxindoles through different amino catalytic activation modes is described herein. Several alkenylisatins were obtained from the Knoevenagel reaction of isatin and activated methylene derivatives containing electron ...
Jessica Navarro Vega   +2 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Intermolecular Michael Reactions: A Computational Investigation [PDF]

open access: yesOrganic Letters, 2010
Computational studies have suggested that η(3)-lithium enolates in which the cation is partially bound to both carbon and oxygen may be important reactive intermediates. DFT calculations are used to demonstrate that explicitly solvated acetone enolates are largely O-bound.
Eugene E, Kwan, David A, Evans
openaire   +2 more sources

A Simple Model for Predicting Sprint Race Times Accounting for Energy Loss on the Curve [PDF]

open access: yes, 1997
The mathematical model of J. Keller for predicting World Record race times, based on a simple differential equation of motion, predicted quite well the records of the day. One of its shortcoming is that it neglects to account for a sprinter's energy loss
Mureika, J. R.
core   +2 more sources

The reaction of cinnamaldehyde and cinnam(o)yl derivatives with thiols

open access: yesActa Pharmaceutica Sinica B, 2017
Spurred by the alleged relevance of the thia-Michael reaction in the bioactivity of various classes of cinnam(o)yl natural products and by the development of a quick NMR assay to study this reaction, we have carried out a systematic study of the “native”
Alessandro Autelitano   +4 more
doaj   +1 more source

Trivinylphosphine Oxide: Synthesis, Characterization, and Polymerization Reactivity Investigated Using Single-Crystal Analysis and Density Functional Theory

open access: yesMolecules, 2023
Organophosphorus chemicals are versatile and important in industry. Trivinylphosphine oxide (TVPO), for example, exhibited a promising precursor as a flame-retardant additive for industrial applications.
Khalifah A. Salmeia   +3 more
doaj   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

open access: yes, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima   +4 more
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Impact of rapeseed press-cake on Maillard reaction in a cookie model system [PDF]

open access: yes, 2018
Rapeseed press-cake (RPC) is a byproduct of rapeseed oil production, rich in proteins and fiber. The aim of this study was to investigate the impact of cold pressed RPC, RPC fiber isolate and RPC alkaline extract on the formation of acrylamide and 5 ...
Fiore, Alberto   +2 more
core   +2 more sources

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