Results 81 to 90 of about 1,004,074 (357)
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Acetoacetate based thermosets prepared by dual-Michael addition reactions [PDF]
, 2019 A novel set of dual-curable multiacetoacetate-multiacrylate-divinyl sulfone ternary materials with versatile and manipulable properties are presented.
Fernández Francos, Xavier +3 more
core +2 more sources
Molecules, 2010 This study describes an attempt to develop a synthetic route using theoretical calculations, i.e., in silico synthesis route development. The KOSP program created four potential synthetic routes for generating 2,6-dimethylchroman-4-one.
Hidetoshi Yamamoto +5 more
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Amine terminated bisaspartimide polymer [PDF]
, 1986 Novel amine terminated bisaspartimides are prepared by a Michael-type reaction of an aromatic bismalteimide and an aromatic diamine in an aprotic solvent.
Fohlen, G. M., Kumar, D., Parker, J. A.
core +1 more source
Molecular Networks in Dynamic Multilevel Systems [PDF]
, 2018 Dynamic multilevel systems can be assembled from molecular building blocks through two or more reversible reactions that form covalent bonds. Molecular networks of dynamic multilevel systems can exhibit different connectivities between nodes.
Cabezudo, Ignacio +4 more
core +1 more source
Michael addition reaction in C-5 of Camptothecin
Journal of Saudi Chemical SocietyA simple method for Michael addition at C-5 of Camptothecin has been developed to construct 5-CPT derivatives. The addition products were obtained with moderate yields, and the structures of the target compounds were characterized by 1H NMR, 13C NMR, and
Changkuo Zhao +3 more
doaj +1 more source
Green synthesis of novel isatin thioketal derivatives under solvent-free conditions
Green Chemistry Letters and Reviews, 2017 A new series of spiro[[1,3]dithiolane-2,3′-indolines]-2′-one derivatives was synthesized using Michael addition reaction of spiro[[1,3]dithiolane-2,3′-indolin]-2′-one to various α,β-unsaturated esters as well as direct alkylation of this compound with ...
Gholamhassan Imanzadeh +3 more
doaj +1 more source
Systematic study of the employment of enzymatic catalysts on the formation of carbon-heteroatoms
Orbital: The Electronic Journal of Chemistry, 2012 The classic thio-Michael reaction is the one that involves the addition of a sulfur atom like the nucleophile of the reaction to an electrophile α,β -insaturated.
Paula Vanessa S. Rizzo +6 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr +5 more
wiley +1 more source