Far-Red Absorbing Rhodopsins, Insights From Heterodimeric Rhodopsin-Cyclases
Frontiers in Molecular Biosciences, 2022 The recently discovered Rhodopsin-cyclases from Chytridiomycota fungi show completely unexpected properties for microbial rhodopsins. These photoreceptors function exclusively as heterodimers, with the two subunits that have very different retinal ...
Matthias Broser
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Ion-pumping microbial rhodopsin protein classification by machine learning approach
BMC Bioinformatics, 2023 Background Rhodopsin is a seven-transmembrane protein covalently linked with retinal chromophore that absorbs photons for energy conversion and intracellular signaling in eukaryotes, bacteria, and archaea.
Muthu Krishnan Selvaraj +6 more
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Nature Communications, 2021 Microbial rhodopsins can be used to control action potentials, while animal opsins can be used to control intracellular signaling pathways. The authors identify Opn7b as constitutively active Gi/o coupled receptor that can be deactivated by light and ...
Raziye Karapinar +10 more
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Applications and challenges of rhodopsin-based optogenetics in biomedicine
Frontiers in Neuroscience, 2022 Optogenetics is an emerging bioengineering technology that has been rapidly developed in recent years by cross-integrating optics, genetic engineering, electrophysiology, software control, and other disciplines.
Hanci Zhang +9 more
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Viral rhodopsins 1 are an unique family of light-gated cation channels
Nature Communications, 2020 Nucleocytoplasmic Large DNA Viruses (NCLDV) that infect algae encode two distinct families of microbial rhodopsins. Here, the authors characterise two proteins form the viral rhodopsin group 1 OLPVR1 and VirChR1, present the 1.4 Å crystal structure of ...
Dmitrii Zabelskii +33 more
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Ion Transport Activity Assay for Microbial Rhodopsin Expressed in Escherichia coli Cells
Bio-Protocol, 2021 Microbial rhodopsins have diverse functions, including roles as light-driven ion pumps, light-gated ion channels, photosensors, and light-regulated enzymes.
Masae Konno +2 more
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Heliorhodopsin Evolution Is Driven by Photosensory Promiscuity in Monoderms
mSphere, 2021 Rhodopsins are light-activated proteins displaying an enormous versatility of function as cation/anion pumps or sensing environmental stimuli and are widely distributed across all domains of life.
Paul-Adrian Bulzu +7 more
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Major Reference Works., 2011 Wiley is pleased to announce the recent acquisition of the prestigious Encyclopedia of Life Sciences (ELS) from the Nature Publishing Group.
"The most ambitious single source reference source ever produced in the biological sciences"
—American Reference Books Annual
Spanning the entire spectrum of life science ...
Peter Hegemann, Carol Dieckmann
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Voltage imaging with engineered proton-pumping Rhodopsins: Insights from the proton transfer pathway [PDF]
, 2023 Voltage imaging using genetically encoded voltage indicators (GEVI) has taken the field of neuroscience by storm in the past decade. Its ability to create subcellular and network level readouts of electrical dynamics depends critically on the kinetics of
Marco, Post +9 more
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mSystems, 2023 Microbial rhodopsins are found more than once in a single genome (paralogs) often have different functions. We screened a large dataset of open ocean single-amplified genomes (SAGs) for co-occurrences of multiple rhodopsin genes.
Jose M. Haro-Moreno +7 more
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