Results 61 to 70 of about 634,170 (178)

Mechanism of voltage-sensitive fluorescence in a microbial rhodopsin [PDF]

Proceedings of the National Academy of Sciences, 2013
Microbial rhodopsins were recently introduced as genetically encoded fluorescent indicators of membrane voltage. An understanding of the mechanism underlying this function would aid in the design of improved voltage indicators. We asked, what states can the protein adopt, and which states are fluorescent?
Dougal, Maclaurin, Veena, Venkatachalam, Hohjai, Lee, Adam E, Cohen   +3 more
openaire   +2 more sources

Evidence of microbial rhodopsins in Antarctic Dry Valley edaphic systems [PDF]

, 2017
Microorganisms able to synthesize rhodopsins have the capacity to translocate ions through their membranes, using solar energy to generate a proton motive force. Rhodopsins are the most abundant phototrophic proteins in oceanic surface waters and are key
Guerrero, Leandro Demián, Leandro D. Guerrero, Don A. Cowan, Makhalanyane, Thulani P., Makhalanyane, Thulani Peter, Cowan, Don A., Guerrero, Leandro D., Vikram, Surendra, Thulani P. Makhalanyane, Surendra Vikram   +9 more
core   +1 more source

Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms

, 2015
Microbial and Animal Rhodopsins: Structures, Functions, and Molecular ...
Oliver P. Ernst (141669), Leonid S. Brown (1305093), Marcus Elstner (394014), Hideki Kandori (1235541), Peter Hegemann (1235085), David T. Lodowski (1305096)   +5 more
core   +1 more source

Prepartum Heat Stress Dysregulates Immune Resilience in Postpartum Dairy Cows

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Increasing environmental temperatures pose a major challenge to animal welfare by inducing heat stress and increasing the incidence of disease. Immune resilience is essential for maintaining animal health; however, the mechanisms linking heat stress to immune dysfunction and disease remain unclear.
Arslan Tariq, Masroor Sagheer, Nicholas C. Kertz, Zachary K. Seekford, Maria A. T. de Bari, Gabriela A. Macay, Sriniwas Pandey, Yuting Zhai, Kwangcheol C. Jeong, Geoffrey E. Dahl, John J. Bromfield   +10 more
wiley   +1 more source

Modified Rhodopsins From Aureobasidium pullulans Excel With Very High Proton-Transport Rates

Frontiers in Molecular Biosciences, 2021
Aureobasidium pullulans is a black fungus that can adapt to various stressful conditions like hypersaline, acidic, and alkaline environments. The genome of A. pullulans exhibits three genes coding for putative opsins ApOps1, ApOps2, and ApOps3.
Sabine Panzer, Chong Zhang, Tilen Konte, Celine Bräuer, Anne Diemar, Parathy Yogendran, Jing Yu-Strzelczyk, Georg Nagel, Shiqiang Gao, Ulrich Terpitz   +9 more
doaj   +1 more source

Biological Systems as Physical Data Processors: Evolution as a Case of Embodied Computing

BioEssays, Volume 48, Issue 10, October 2026.
Embodied biological computing is process through which biological systems gravitate toward attractors in a solution space through a thermodynamically favored process of information capture. Applications in biotechnology, in particular metabolic engineering are numerous.
Víctor de Lorenzo
wiley   +1 more source

Dual‐Laser Laser‐Induced Liquid Bead Ion Desorption Mass Spectrometry: A New Approach for Adjustable Softness and Higher Sensitivity

ChemPhysChem, Volume 27, Issue 14, 29 July 2026.
Native protein complexes often require gentle ionization to preserve weak interactions, yet higher ion yield typically goes hand in hand with increased in‐source dissociation. Our dual‐laser LILBID approach decouples ion production from dissociation by using two independently tunable pulses, enabling sample‐specific soft conditions and expanding access
Niko Popovic, Jonathan Schulte, Anne Mayer, Clemens Glaubitz, Nina Morgner   +4 more
wiley   +1 more source

Gut Microbiota‐Derived Bacterial Extracellular Vesicles in COVID‐19: Their Signature and Immunological Impact

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
This study demonstrated that the secretion of bacterial extracellular vesicles (BEVs) changes during COVID‐19‐induced gut‐bacterial dysbiosis, and these alterations in BEV profiles influence the immune cell cytokine response, persisting even after clinical remission.
Aya Ishizaka, Michiko Koga, Tomoya Hayashi, Ken J Ishii, Hiroyuki Yamamoto, Hiroshi Yotsuyanagi, Taketoshi Mizutani   +6 more
wiley   +1 more source

Mimicking Microbial Rhodopsin Isomerization in a Single Crystal [PDF]

Journal of the American Chemical Society, 2018
Bacteriorhodopsin represents the simplest, and possibly most abundant, phototropic system requiring only a retinal-bound transmembrane protein to convert photons of light to an energy-generating proton gradient. The creation and interrogation of a microbial rhodopsin mimic, based on an orthogonal protein system, would illuminate the design elements ...
Alireza Ghanbarpour, Muath Nairat, Meisam Nosrati, Elizabeth M. Santos, Chrysoula Vasileiou, Marcos Dantus, Babak Borhan, James H. Geiger   +7 more
openaire   +2 more sources

Hydrostatic pressure spectroscopy reveals the adaptation of microbial rhodopsins to high-pressure environment

Scientific Reports
Microbial rhodopsins are light-driven membrane proteins that convert photon energy into biological functions via photocycles initiated by retinal chromophore isomerization. Although their structural and functional properties under ambient conditions have
Tomoyuki Hamachi, Iori Okamura, Lyu Zikun, Kentaro Mannen, Yoshitaka Kato, Takashi Nagata, Keiichi Inoue, Gaku Fukuhara   +7 more
doaj   +1 more source