Results 51 to 60 of about 15,118,660 (165)
Frontiers in Oncology, 2022 BackgroundThe present study aims to evaluate dosimetric and clinical risk factors for the development of maxillary osteoradionecrosis (ORN) in head and neck adenoid cystic carcinoma (ACC) patients treated with carbon ion radiotherapy (CIRT ...
Barbara Vischioni +14 more
doaj +1 more source
Relative biological effectiveness study of Lipiodol based on microdosimetric-kinetic model
Physica Medica, 2018 We examine the contrast agent Lipiodol effect on the relative biological effectiveness (RBE) values for flattening filter free (FFF) and flattening filter (FF) beams of 6 MV-Xray (6 MVX) and 10 MVX.Lipiodol was placed at 5 cm depth in water. According to the microdosimetric kinetic model, the RBE values for killing the human liver hepatocellular cells ...
Daisuke Kawahara +10 more
openaire +3 more sources
Physica Medica, 2021 To implement RBE calculations in treatment planning systems based on the Microdosimetric Kinetic Model (MKM) upon analytical calculations of dose-mean lineal energy (yD). MKM relies on the patterns of energy deposition in sub-nuclear structures called domains, whose radii are cell-specific and need to be determined.The radius of a domain (rd) can be ...
A. Bertolet +2 more
openaire +3 more sources
Equivalent relative biological effectiveness for cell survival and micronuclei formation: insights from a biophysical approach. [PDF]
Med PhysAbstract Background Micronuclei (MN), which are chromosome fragments, are formed after exposure to ionizing radiation. Radiation‐induced MN is currently used as a quantitative indicator of the chromosomal aberrations detectable at a relatively early phase (e.g., within one cell‐cycle progression).
Matsuya Y, Saga R, Wang Y, Sato T.
europepmc +2 more sources
Spot-Scanning Hadron Arc (SHArc) Therapy: A Study With Light and Heavy Ions
Advances in Radiation Oncology, 2021 Purpose: To evaluate the clinical potential of spot-scanning hadron arc (SHArc) therapy with a heavy-ion gantry. Methods and Materials: A series of in silico studies was conducted via treatment plan optimization in FRoG and the RayStation TPS to compare ...
Stewart Mein, PhD +7 more
doaj +1 more source
Radiation Oncology, 2023 Background The study objective was to validate the relative biological effectiveness (RBE) calculated by the modified microdosimetric kinetic model in RayStation (Ray-MKM) for active-energy scanning carbon-ion radiotherapy.
Weiwei Wang +3 more
doaj +1 more source
Radiation Oncology, 2021 Background The study objective was to establish the local effect model (LEM) rectum constraints for 12-, 8-, and 4-fraction carbon-ion radiotherapy (CIRT) in patients with localized prostate carcinoma (PCA) using microdosimetric kinetic model (MKM ...
Weiwei Wang +8 more
doaj +1 more source
Conservative numerical methods for model kinetic equations [PDF]
, 2007 A new conservative discrete ordinate method for nonlinear model kinetic equations is proposed. The conservation property with respect to the collision integral is achieved by satisfying at the discrete level approximation conditions used in deriving the ...
Titarev, Vladimir A.
core +1 more source
Microdosimetric concepts relevant to HZE-particles [PDF]
, 1977 The biological effectiveness of HZE-particles i s determined by the extreme microscopic concentrations of energy transfer in the vicinity of the particle tracks. The concept of linear energy transfer fails to describe this situation adequately.
Kellerer, Albrecht M., Burke, W. R.
core +1 more source
Integrating microdosimetric in vitro RBE models for particle therapy into TOPAS MC using the MicrOdosimetry-based modeling for RBE Assessment (MONAS) tool [PDF]
, 2023 We present MONAS (MicrOdosimetry-based modelliNg for relative biological effectiveness (RBE) ASsessment) toolkit. MONAS is a TOPAS Monte Carlo extension, that combines simulations of microdosimetric distributions with radiobiological microdosimetry-based
Cartechini, Giorgio +4 more
core +1 more source