Results 51 to 60 of about 1,371 (176)
RadiationMicrodosimetry plays a critical role in particle therapy by quantifying energy deposition within microscopic domains to assess biological effects. This study evaluates the influence of different microdosimetric functions (MFs) and domain geometries (DGs)
Shannon Hartzell +7 more
doaj +1 more source
Radiation Oncology, 2021 Background The study objective was to establish the local effect model (LEM) rectum constraints for 12-, 8-, and 4-fraction carbon-ion radiotherapy (CIRT) in patients with localized prostate carcinoma (PCA) using microdosimetric kinetic model (MKM ...
Weiwei Wang +8 more
doaj +1 more source
Comparison of Integrated Radiation Transport Models with TEPC Measurements for the Average Quality Factors in Spaceflights [PDF]
, 2007 The purpose of this work is to test our theoretical model for the interpretation of radiation data measured in space. During the space missions astronauts are exposed to the complex field of radiation type and kinetic energies from galactic cosmic rays ...
Cucinotta, Francis A. +4 more
core +2 more sources
Equivalency of the quality of sublethal lesions after photons and high-linear energy transfer ion beams [PDF]
, 2017 The quality of the sublethal damage (SLD) after irradiation with high–linear energy transfer (LET) ion beams was investigated with low-LET photons. Chinese hamster V79 cells and human squamous carcinoma SAS cells were first exposed to a priming dose of ...
Furusawa Yoshiya +6 more
core +1 more source
Interpreting the biological effects of protons as a function of physical quantity: linear energy transfer or microdosimetric lineal energy spectrum? [PDF]
Sci RepThe choice of appropriate physical quantities to characterize the biological effects of ionizing radiation has evolved over time coupled with advances in scientific understanding.
Guan F +10 more
europepmc +3 more sources
Scientific Reports, 2017 We introduce an approach for global fitting of the recently published high-throughput and high accuracy clonogenic cell-survival data for therapeutic scanned proton beams.
Ramin Abolfath +5 more
doaj +1 more source
Monte Carlo study on fetal dose assessment for carbon beam craniospinal irradiation during pregnancy
Medical Physics, Volume 53, Issue 3, March 2026.Abstract Background Radiotherapy may be suggested for pregnant cancer patients when treatment cannot be delayed, with careful targeting to minimize fetal dose. Considering that a successful case for a pregnant patient treated with proton beam craniospinal irradiation (CSI) was reported, carbon therapy can be also considered applicable for the CSI ...
Ji Won Choi +8 more
wiley +1 more source
PLoS ONE, 2014 We here propose a new model assembly for estimating the surviving fraction of cells irradiated with various types of ionizing radiation, considering both targeted and nontargeted effects in the same framework.
Tatsuhiko Sato, Nobuyuki Hamada
doaj +1 more source
Medical Physics, Volume 53, Issue 3, March 2026.Abstract Background Associated normal tissue toxicity from current radiotherapy (RT) treatments limits effective dose escalation in the tumor to achieve nominal treatment results. Gold nanoparticles (GNPs) as radiosensitizing agents to locally increase photoelectron production have gained interest as a safe and viable method to improve therapeutic ...
Daniel Cecchi +6 more
wiley +1 more source
Restoring the encoding properties of a stochastic neuron model by an exogenous noise [PDF]
, 2015 Here we evaluate the possibility of improving the encoding properties of an impaired neuronal system by superimposing an exogenous noise to an external electric stimulation signal. The approach is based on the use of mathematical neuron models consisting
APOLLONIO, Francesca +4 more
core +1 more source