Results 51 to 60 of about 686 (148)

Accessing radiation damage to biomolecules on the nanoscale by particle-scattering simulations

Journal of Physics Communications, 2023
Radiation damage to DNA plays a central role in radiation therapy to cure cancer. The physico-chemical and biological processes involved encompass huge time and spatial scales.
Marc Benjamin Hahn
doaj   +1 more source

Characterizing Radiation Effectiveness in Ion Beam Therapy Part I: Introduction and Biophysical Modeling of RBE Using the LEMIV

Frontiers in Physics, 2020
The specific advantages of ion beams for application in tumor therapy are attributed to their different macroscopic and microscopic energy deposition pattern as compared to conventional photon radiation.
Michael Scholz, Thomas Friedrich, Giulio Magrin, Paolo Colautti, Aleksandra Ristić-Fira, Ivan Petrović   +5 more
doaj   +1 more source

Study on Caenorhabditis Elegans as a Combined Model of Microdosimetry and Biology

Dose-Response, 2021
Microdosimetry is a tool for the investigation of microscopic energy deposition of ionizing radiation. This work used Caenorhabditis elegans as a model to estimate the microdosimetric deposition level at the 60 Co gamma radiation.
Wentao Yu, Huiqiang Long, Jin Gao, Yidi Wang, Yu Tu, Liang Sun, Na Chen   +6 more
doaj   +1 more source

Microdosimetry: Principles and applications [PDF]

Reports of Practical Oncology & Radiotherapy, 2016
to present the most important aspects of Microdosimetry, a research field in radiation biophysics.microdosimetry is the branch of radiation biophysics that systematically studies the spatial, temporal and spectral aspects of the stochastic nature of the energy deposition processes in microscopic structures.we briefly review its history, the people, the
openaire   +2 more sources

Editorial: 3rd International Workshop on Microdosimetry for Particle Therapy: Bridging Physics and Biology

Precision Radiation Oncology, EarlyView.
Sandra Barna, Valeria Conte, Francesco Cordoni, Marta Missiaggia, Fada Guan, Anatoly Rozenfeld, Gustavo Santa Cruz, Tatsuhiko Sato, Giuseppe Schettino, Chiara La Tessa   +9 more
wiley   +1 more source

Impact of Microdosimetric Modeling on Computation of Relative Biological Effectiveness for Carbon Ion Radiotherapy

Radiation
Microdosimetry plays a critical role in particle therapy by quantifying energy deposition within microscopic domains to assess biological effects. This study evaluates the influence of different microdosimetric functions (MFs) and domain geometries (DGs)
Shannon Hartzell, Keith M. Furutani, Alessio Parisi, Tatsuhiko Sato, Yuki Kase, Christian Deglow, Thomas Friedrich, Chris J. Beltran   +7 more
doaj   +1 more source

Simulating microdosimetry in a virtual hepatic lobule. [PDF]

PLoS Computational Biology, 2010
The liver plays a key role in removing harmful chemicals from the body and is therefore often the first tissue to suffer potentially adverse consequences.
John Wambaugh, Imran Shah
doaj   +1 more source

Radiation quality assessment in a clinical helium-ion beam using a SOI microdosimeter and a Timepix3 detector

Frontiers in Physics
Accurate characterization of radiation quality is essential for assessing radiobiological effects in radiotherapy, yet remains a major challenge. As modern treatment strategies increasingly consider not only absorbed dose but also linear energy transfer (
Yasmin Hamad, Yasmin Hamad, Yasmin Hamad, Yasmin Hamad, Sandra Barna, Sandra Barna, Giulio Magrin, Hugo Palmans, Hugo Palmans, Ferisya Kusuma Sari, Tim Gehrke, Tim Gehrke, Tim Gehrke, Andrea Mairani, Andrea Mairani, Andrea Mairani   +15 more
doaj   +1 more source

Microdosimetry of kidney cells exposed to 243Am and X-ray irradiation [PDF]

EPJ Web of Conferences
In vitro experiments with rat kidney cells exposed to 243Am in cell culture medium show a decreasing cell viability with increasing americium concentration.
Kahle Pia, Senwitz Christian, Heller Anne, Seifert Anja, Taut Steffen, Kormoll Thomas   +5 more
doaj   +1 more source

Silicon 3D Microdetectors for Microdosimetry in Hadron Therapy

Micromachines, 2020
The present overview describes the evolution of new microdosimeters developed in the National Microelectronics Center in Spain (IMB-CNM, CSIC), ranging from the first ultra-thin 3D diodes (U3DTHINs) to the advanced 3D-cylindrical microdetectors, which ...
Consuelo Guardiola, Celeste Fleta, David Quirion, Giulio Pellegrini, Faustino Gómez   +4 more
doaj   +1 more source