Results 21 to 30 of about 25,497 (250)
Observations Of Microfilament Bundles In Living Cells Microinjected With Fluorescently Labelled Contractile Proteins [PDF]
Journal of Cell Science, 1986 ABSTRACT Fluorescently labelled contractile proteins (alpha-actinin and filamin) were used to study the dynamic nature of three types of microfilament bundles: myofibrils, stress fibres and polygonal networks. Cultured muscle and non-muscle cells that were microinjected with fluorescent alphaactinin rapidly incorporated the labelled ...
Jean M. Sanger +3 more
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Regulation of Apicomplexan Microfilament Dynamics by a Minimal Set of Actin‐Binding Proteins [PDF]
Traffic, 2006 Efficient and rapid host cell invasion is a prerequisite for an intracellular parasitic life style. Pathogens typically induce receptor‐mediated endocytosis and hijack the force‐transducing system of a host cell to gain access to a replication‐competent niche.
H. Schüler, Kai Matuschewski
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Microfilament dynamics during cell movement and chemotaxis monitored using a GFP–actin fusion protein [PDF]
Current Biology, 1997 The microfilament system in the cortex of highly motile cells, such as neutrophils and cells of the eukaryotic microorganism Dictyostelium discoideum, is subject to rapid re-organization, both spontaneously and in response to external signals. In particular, actin polymerization induced by a gradient of chemoattractant leads to local accumulation of ...
Monika Westphal +7 more
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Dephosphorylated but not phosphorylated microtubule associated protein MAP1B binds to microfilaments [PDF]
FEBS Letters, 1996 We have reported that purified native MAP1B interacts with microtubules but not with microfilaments [Pedrotti and Islam, Cell Motil. Cytoskel. (1995) 30, 301–309]. However, MAP1B can be phosphorylated at multiple sites by casein kinase II (CKII) and proline‐directed protein kinases (PDPK) and immunoblotting studies show that purified native MAP1B is ...
Barbara Pedrotti, Khalid Islam
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International Journal of Oral Science, 2022 Microenvironmental biophysical factors play a fundamental role in controlling cell behaviors including cell morphology, proliferation, adhesion and differentiation, and even determining the cell fate.
Chenchen Zhou +5 more
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The Significant Role of the Microfilament System in Tumors
Frontiers in Oncology, 2021 Actin is the structural protein of microfilaments, and it usually exists in two forms: monomer and polymer. Among them, monomer actin is a spherical molecule composed of a polypeptide chain, also known as spherical actin.
Xin Jiang +6 more
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Suppression of Tumorigenicity in Breast Cancer Cells by the Microfilament Protein Profilin 1 [PDF]
The Journal of Experimental Medicine, 2000 Differential display screening was used to reveal differential gene expression between the tumorigenic breast cancer cell line CAL51 and nontumorigenic microcell hybrids obtained after transfer of human chromosome 17 into CAL51. The human profilin 1 (PFN1) gene was found overexpressed in the microcell hybrid clones compared with the parental line ...
Jürgen Janke +11 more
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Villin: The major microfilament-associated protein of the intestinal microvillus [PDF]
Proceedings of the National Academy of Sciences, 1979 The major protein associated with actin in the microfilament core of intestinal microvilli has been purified. This protein, for which we propose the name villin, has a polypeptide molecular weight of approximately 95,000. Two arguments suggest that villin may be the microvillus crossfilament protein that links the microfilament core laterally down its ...
A, Bretscher, K, Weber
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Scientific Reports, 2023 mTOR complex 2 (mTORC2) has been implicated as a key regulator of glioblastoma cell migration. However, the roles of mTORC2 in the migrational control process have not been entirely elucidated.
Naphat Chantaravisoot +8 more
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Role of hypoxia in promoting migration and cell fusion of urine-derived stem cells
陆军军医大学学报, 2023 Objective To explore the effect of hypoxia on cell migration and fusion of urine-derived stem cells (USCs) in vitro, and observe the changes in cytoskeleton and cell polarity during the process.
ZHANG Nannan, HU Chaoqun, HE Yun
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