Results 21 to 30 of about 5,523,474 (277)
MicroRNAs (miRNAs) play an essential role in the regulation of a number of physiological functions. miR-133a and other muscular miRs (myomiRs) play a key role in muscle cell growth and in some type of cancers. Here, we show that miR133a is upregulated in
S. Caporali+11 more
semanticscholar +1 more source
BPAG1a and b associate with EB1 and EB3 and modulate vesicular transport, Golgi apparatus structure, and cell migration in C2.7 myoblasts. [PDF]
BPAG1a and BPAG1b (BPAG1a/b) constitute two major isoforms encoded by the dystonin (Dst) gene and show homology with MACF1a and MACF1b. These proteins are members of the plakin family, giant multi-modular proteins able to connect the intermediate ...
Kseniia Poliakova+6 more
doaj +1 more source
Involvement of the Actin Machinery in Programmed Cell Death
Programmed cell death (PCD) depicts a genetically encoded and an orderly mode of cellular mortality. When triggered by internal or external stimuli, cells initiate PCDs through evolutionary conserved regulatory mechanisms.
Weida Ren+3 more
doaj +1 more source
Microenvironmental biophysical factors play a fundamental role in controlling cell behaviors including cell morphology, proliferation, adhesion and differentiation, and even determining the cell fate.
Chenchen Zhou+5 more
doaj +1 more source
Villin: The major microfilament-associated protein of the intestinal microvillus [PDF]
The major protein associated with actin in the microfilament core of intestinal microvilli has been purified. This protein, for which we propose the name villin, has a polypeptide molecular weight of approximately 95,000. Two arguments suggest that villin may be the microvillus crossfilament protein that links the microfilament core laterally down its ...
Anthony Bretscher, Klaus Weber
openaire +3 more sources
Stimuli-responsive assembly of iron oxide nanoparticles into magnetic flexible filaments [PDF]
The combination of multiple functionalities in a single material is an appealing strategy for the de-velopment of smart materials with unique features. In this work, we present the preparation of thermoresponsive magnetic nanoparticles and their one-dimensional assembly into transient micro-filaments.
arxiv +1 more source
mTOR complex 2 (mTORC2) has been implicated as a key regulator of glioblastoma cell migration. However, the roles of mTORC2 in the migrational control process have not been entirely elucidated.
Naphat Chantaravisoot+8 more
doaj +1 more source
Role of hypoxia in promoting migration and cell fusion of urine-derived stem cells
Objective To explore the effect of hypoxia on cell migration and fusion of urine-derived stem cells (USCs) in vitro, and observe the changes in cytoskeleton and cell polarity during the process.
ZHANG Nannan, HU Chaoqun, HE Yun
doaj +1 more source
Neurotrophic extracellular matrix proteins promote neuronal and iPSC astrocyte progenitor cell- and nano-scale process extension for neural repair applications. [PDF]
The extracellular matrix plays a critical role in modulating cell behaviour in the central nervous system influencing neural cell morphology and growth. However, a better understanding of the impact of individual matrix proteins on both neurons and astrocytes is critical for advancing the development of matrix‐based neural repair strategies.
O'Connor C+9 more
europepmc +2 more sources
Modulation of Microfilament Protein Composition by Transfected Cytoskeletal Actin Genes [PDF]
HuT-14T is a highly tumorigenic fibroblast cell line which exhibits a reduced steady-state level of beta-actin due to coding mutations in one of two beta-actin alleles. The normal rate of total actin synthesis could be restored in some clones of cells following transfection of the functional beta-actin gene but not following transfection of the ...
L Kedes+4 more
openaire +3 more sources