Results 21 to 30 of about 24,781 (265)
Profilin and actin-related proteins regulate microfilament dynamics during early mammalian embryogenesis [PDF]
Human Reproduction, 2006 Profilins are ubiquitous proteins widely distributed in animals, including humans. They regulate actin polymerization by sequestering actin monomers in association with other actin-related proteins (Arps). Actin remodelling is essential for oocyte maturation, fertilization and embryo development; yet the role of profilins in these events is not well ...
Vanesa Y. Rawe +2 more
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Biomolecules, 2021 Human skin fibroblasts (HSFs) approximate the multidirectional differentiation potential of mesenchymal stem cells, so they are often used in differentiation, cell cultures, and injury repair. They are an important seed source in the field of bone tissue
Xiaolan Huang +12 more
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Signaling via ITGB1/FAK and microfilament rearrangement mediates the internalization of Leptospira interrogans in mouse J774A.1 macrophages [PDF]
Archives of Biological Sciences, 2015 Leptospirosis caused by pathogenic Leptospira species is a worldwide zoonotic 2 infectious disease, but the mechanisms of leptospiral internalization remain poorly understood.
Zhao Xin +4 more
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Frontiers in Pharmacology, 2020 Microcystin-leucine arginine (MC-LR) is a potent tumor initiator that can induce malignant cell transformation. Cellular mechanical characteristics are pivotal parameters that are closely related to cell invasion.
Qiang Zhang +7 more
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BPAG1a and b associate with EB1 and EB3 and modulate vesicular transport, Golgi apparatus structure, and cell migration in C2.7 myoblasts. [PDF]
PLoS ONE, 2014 BPAG1a and BPAG1b (BPAG1a/b) constitute two major isoforms encoded by the dystonin (Dst) gene and show homology with MACF1a and MACF1b. These proteins are members of the plakin family, giant multi-modular proteins able to connect the intermediate ...
Kseniia Poliakova +6 more
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Involvement of the Actin Machinery in Programmed Cell Death
Frontiers in Cell and Developmental Biology, 2021 Programmed cell death (PCD) depicts a genetically encoded and an orderly mode of cellular mortality. When triggered by internal or external stimuli, cells initiate PCDs through evolutionary conserved regulatory mechanisms.
Weida Ren +3 more
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International Journal of Oral Science, 2022 Microenvironmental biophysical factors play a fundamental role in controlling cell behaviors including cell morphology, proliferation, adhesion and differentiation, and even determining the cell fate.
Chenchen Zhou +5 more
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The Significant Role of the Microfilament System in Tumors
Frontiers in Oncology, 2021 Actin is the structural protein of microfilaments, and it usually exists in two forms: monomer and polymer. Among them, monomer actin is a spherical molecule composed of a polypeptide chain, also known as spherical actin.
Xin Jiang +6 more
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Scientific Reports, 2023 mTOR complex 2 (mTORC2) has been implicated as a key regulator of glioblastoma cell migration. However, the roles of mTORC2 in the migrational control process have not been entirely elucidated.
Naphat Chantaravisoot +8 more
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Role of hypoxia in promoting migration and cell fusion of urine-derived stem cells
陆军军医大学学报, 2023 Objective To explore the effect of hypoxia on cell migration and fusion of urine-derived stem cells (USCs) in vitro, and observe the changes in cytoskeleton and cell polarity during the process.
ZHANG Nannan, HU Chaoqun, HE Yun
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