Results 21 to 30 of about 24,177 (264)
Association of CHMP4B and autophagy with micronuclei : implications for cataract formation [PDF]
, 2014 Autophagy is a mechanism of cellular self-degradation that is very important for cellular homeostasis and differentiation. Components of the endosomal sorting complex required for transport (ESCRT) machinery are required for endosomal sorting and also ...
Nezis, Ioannis P. +2 more
core +1 more source
Micronuclei, reproduction and child health
Mutation Research/Reviews in Mutation Research, 2021 The current review looks for relationships between results from biomarker studies with micronucleus and health effects related to reproduction and children. In adults, an age related increase in MN is well known as well as associations with environmental exposures especially air pollution from traffic and smoking.
Knudsen, Lisbeth E. +1 more
openaire +4 more sources
Automated Detection of Binucleated Cell and Micronuclei using CellProfiler 2.0 Software
Hayati Journal of Biosciences, 2013 Micronucleus assay in human peripheral lymphocytes usually used to assess chromosomal damage. Manual scoring of micronuclei can be time consuming and large numbers of binucleated cells have to be analyzed to obtain statistically relevant data. Automation
DWI RAMADHANI, SOFIATI PURNAMI
doaj +1 more source
Paternal cyclophosphamide exposure induces the formation of functional micronuclei during the first zygotic division. [PDF]
PLoS ONE, 2011 Paternal exposures to cancer chemotherapeutics or environmental chemicals may have adverse effects on progeny outcome that are manifested in the preimplantation embryo.
Lisanne Grenier +2 more
doaj +1 more source
cGAS localizes in DNA damage induced micronuclei.
, 2022 Micronuclei formation in HPV positive cells and cGAS co-localization (left panel) post etoposide treatment for 24hrs at 50μM. Quantitation of micronuclei from three independent experiments and two different clones of CIN612 pLenti control or cGAS-KO ...
Laimonis A. Laimins (13149963) +1 more
core +1 more source
Environmental Health, 2017 Background Ionizing radiation is a well-known carcinogen. Chromosome aberrations, and in particular micronuclei represent an early biological predictor of cancer risk.
D. Bazyka +11 more
doaj +1 more source
Toxics, 2022 The WHO classified air pollution as a human lung carcinogen and polycyclic aromatic hydrocarbons (PAHs) are components of both indoor (e.g., tobacco smoke and cookstoves) and outdoor (e.g., wildfires and industrial and vehicle emissions) air pollution ...
Alison K. Bauer +7 more
doaj +1 more source
Frontiers in Public Health, 2021 The effect of the reportedly low ionizing radiation doses, such as those very often delivered to patients in interventional cardiology, remains ambiguous.
Martha Habibi +13 more
doaj +1 more source
Micronuclei as a predictor for oral carcinogenesis
Journal of Cytology, 2018 The aim of the study was to provide a quantitative evaluation of oral mucosal micronuclei (MN) frequency as a biomarker for oral cancer susceptibility in carcinogenesis progression.60 patients were included in the study. 30 patients with biopsy proven epithelial dysplasia (ED, 15) and oral squamous cell carcinoma (OSCC, 15) comprised the study group ...
Kamini Kiran +3 more
openaire +3 more sources
Frontiers in Cell and Developmental Biology, 2022 Some eukaryotes exhibit dramatic genome size differences between cells of different organs, resulting from the programmed elimination of chromosomes. Aegilops speltoides is an annual diploid species from the Poaceae family, with a maximum number of eight
Daiyan Li +8 more
doaj +1 more source