Results 31 to 40 of about 37,562 (240)
Catastrophic chromosomal restructuring during genome elimination in plants. [PDF]
, 2015 Genome instability is associated with mitotic errors and cancer. This phenomenon can lead to deleterious rearrangements, but also genetic novelty, and many questions regarding its genesis, fate and evolutionary role remain unanswered.
Bradnam, Keith R +9 more
core +1 more source
Properties of grape seed proanthocyanidins and quercetin in human lymphocytes [PDF]
Archives of Biological Sciences, 2008 This study addresses the in vitro protective effects of proanthocyanidins and quercetin on the frequency of micronuclei with reference to the antioxidant status of cultured human lymphocytes also subjected to 2 Gy of γ-radiation. Treatment of lymphocytes
Stanković Miroslava, Horvat Anica
doaj +1 more source
Toxics, 2022 The WHO classified air pollution as a human lung carcinogen and polycyclic aromatic hydrocarbons (PAHs) are components of both indoor (e.g., tobacco smoke and cookstoves) and outdoor (e.g., wildfires and industrial and vehicle emissions) air pollution ...
Alison K. Bauer +7 more
doaj +1 more source
Genotoxic and stress inductive potential of cadmium in Xenopus laevis larvae [PDF]
, 2006 The present investigation evaluates the toxic potential of Cd in larvae of the frog Xenopus laevis after 12 days of exposure to environmentally relevant contamination levels, close to those measured in the river Lot (France).
Baudrimont, Magalie +6 more
core +3 more sources
Scientific Reports, 2019 Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease with no known etiology. The formation of pathological protein inclusions, including RNA-binding proteins such as TDP-43 and rho guanine nucleotide exchange factor (
Cristian A. Droppelmann +4 more
doaj +1 more source
Active DNA end processing in micronuclei of ovarian cancer cells
BMC Cancer, 2018 Background Ovarian cancer is one of the most deadly gynecological malignancies and inclined to recurrence and drug resistance. Previous studies showed that the tumorigenesis of ovarian cancers and their major histotypes are associated with genomic ...
Zizhi Tang +10 more
doaj +1 more source
Fluorescence in situ hybridisation study of micronuclei in C3A cells following exposure to ELF-magnetic fields [PDF]
, 2019 Human C3A cells were exposed to extremely low frequency (50 Hz) magnetic fields (ELF-MF's) up to 500 mu T. They were subjected to the micronucleus assay using a Fluorescence In Situ Hybridization (FISH) technique with an in-house pan-centromere probe. We
Antonissen, Roel +4 more
core +1 more source
Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle. [PDF]
, 2019 Migration through 3D constrictions can cause nuclear rupture and mislocalization of nuclear proteins, but damage to DNA remains uncertain, as does any effect on cell cycle.
Bannister +77 more
core +1 more source
Is there a causal association between genotoxicity and the imposex effect? [PDF]
, 2006 There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Josephine A. Hagger +13 more
core +2 more sources
Mutagenic impact on fish of runoff events in agricultural areas in south-west France [PDF]
, 2011 When heavy rainfall follows herbicide application, the intense surface runoff causes stream water contamination. Aquatic organisms are then briefly exposed to a complex mixture of contaminants.
Gauthier, Laury +6 more
core +2 more sources