Results 41 to 50 of about 37,562 (240)

Genotoxic effects of the diesel water-soluble fraction on the seahorse Hippocampus reidi (Teleostei: Syngnathidae) during acute exposure

Zoologia (Curitiba), 2010
The high toxicity of diesel components makes oil spills a threat to the biota in coastal marine environments. The genotoxic effect of the diesel water-soluble fraction (DWSF) on Hippocampus reidi (Ginsburg, 1933) was assessed.
Celina Alcoforado Santos, Larissa Simões Novaes, Levy Carvalho Gomes   +2 more
doaj   +1 more source

The Use of Genotoxicity Endpoints as Biomarkers of Low Dose Radiation Exposure in Interventional Cardiology

Frontiers in Public Health, 2021
The effect of the reportedly low ionizing radiation doses, such as those very often delivered to patients in interventional cardiology, remains ambiguous.
Martha Habibi, Martha Habibi, Panagiotis K. Karyofyllis, Aggeliki Nikolakopoulou, Aggeliki Nikolakopoulou, Panagiotis Papagiannis, Pantelis Karaiskos, Alexandros G. Georgakilas, Vasiliki I. Hatzi, Ioannis Malakos, Nikolaos Kollaros, Irene Mastorakou, Vassilis Voudris, Georgia I. Terzoudi   +13 more
doaj   +1 more source

B-A Chromosome Translocations Possessing an A Centromere Partly Overcome the Root-Restricted Process of Chromosome Elimination in Aegilops speltoides

Frontiers in Cell and Developmental Biology, 2022
Some eukaryotes exhibit dramatic genome size differences between cells of different organs, resulting from the programmed elimination of chromosomes. Aegilops speltoides is an annual diploid species from the Poaceae family, with a maximum number of eight
Daiyan Li, Daiyan Li, Daiyan Li, Alevtina Ruban, Alevtina Ruban, Jörg Fuchs, Houyang Kang, Houyang Kang, Andreas Houben   +8 more
doaj   +1 more source

Genotoxicity assessment of piperitenone oxide: an in vitro and in silico evaluation [PDF]

, 2017
Piperitenone oxide, a natural flavouring agent also known as rotundifolone, has been studied for the genotoxicity assessment by an integrated in vitro and in silico experimental approach, including the bacterial reverse mutation assay, the micronucleus ...
Abete, Lorena, Barile, Fabio, Bozovic, Mijat, DI GIACOMO, Silvia, DI SOTTO, Antonella, Izzo, Angelo A, Mazzanti, Gabriela, Parisi, Olga A, Ragno, Rino, Vitalone, Annabella   +9 more
core   +1 more source

Genotoxicity in oral mucosal epithelial cells of petrol station attendants: A micronucleus study

Journal of Cytology, 2021
Introduction: Occupational exposure to petrol derivatives possesses an increased risk of various cancers including that of the oral mucosa. Scientific studies have shown the correlation of micronuclei assay (MN) with the cytogenotoxic changes in petrol ...
Shweta Rehani, Naresh Raj, Prabhakar Jeergal, Mohit Sharma, Kundendu Arya Bishen, Ruchi Nagpal   +5 more
doaj   +1 more source

An Automated, Single Cell Quantitative Imaging Microscopy Approach to Assess Micronucleus Formation, Genotoxicity and Chromosome Instability

Cells, 2020
Micronuclei are small, extranuclear bodies that are distinct from the primary cell nucleus. Micronucleus formation is an aberrant event that suggests a history of genotoxic stress or chromosome mis-segregation events.
Chloe C. Lepage, Laura L. Thompson, Bradley Larson, Kirk J. McManus   +3 more
doaj   +1 more source

Micronuclei assay by laser scanning cytometry [PDF]

Cytometry, 2001
The micronuclei (MN) assay is used to assess the chromosomal/mitotic spindle damage induced by ionizing radiation or mutagenic agents in vivo or in vitro. Because visual scoring of MN is cumbersome semi-automatic procedures that relay either on flow cytometry or image analysis were developed: both offer some advantages but also have shortcomings.In the
P, Smolewski, Q, Ruan, L, Vellon, Z, Darzynkiewicz   +3 more
openaire   +2 more sources

Evaluation of genotoxic effect of amalgam restorations in oral cavity

Journal of Orofacial Sciences, 2015
Background: Mercury a popular heavy metal used in dentistry in the form of amalgam is a known clastogen. The assessment of micronuclei in cells is a promising tool for studying the genotoxic effect of mercury on them.
Chennoju Sai Kiran, Reddy Sudhakara Reddy, Rajesh Nallakunta   +2 more
doaj   +1 more source

Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype

Advanced Functional Materials, EarlyView.
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He, Wang Sik Lee, Phattadon Yajan, Aaron Lee, Mauro Sousa de Almeida, Sandeep Keshavan, Jozef Adamcik, Céline Loussert‐Fonta, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +10 more
wiley   +1 more source

The effects of sex, age and cigarette smoking on micronucleus and degenerative nuclear alteration frequencies in human buccal cells of healthy Bosnian subjects

Journal of Health Sciences, 2013
Introduction: This study was performed to establish a baseline value of micronucleus frequency in buccal cells and to estimate the impact of the most common factors (sex and age, and smoking) on micronucleus and degenerative nuclear alteration ...
Hilada Nefić, Jasmin Mušanović, Kemajl Kurteshi, Enida Prutina, Elvira Turcalo   +4 more
doaj   +1 more source