Cells, 2020 Micronuclei are small, extranuclear bodies that are distinct from the primary cell nucleus. Micronucleus formation is an aberrant event that suggests a history of genotoxic stress or chromosome mis-segregation events.
Chloe C. Lepage +3 more
doaj +2 more sources
Micronucleus study on breast cytology aspirate smears and its diagnostic utility
Journal of Cytology, 2018 Background: Micronucleus is a small fragment of nucleus present in the cells which have undergone chromosomal damage. It is used as a biomarker of genomic damage. Aims: We aim to study the presence of micronucleus on breast cytology smears and the use of
Mary T Sylvia +2 more
doaj +2 more sources
Effect of Sodium Benzoate Preservative on Micronucleus Induction, Chromosome Break, and Ala40Thr Superoxide Dismutase Gene Mutation in Lymphocytes [PDF]
BioMed Research International, 2015 Sodium benzoate is food preservative that inhibits microbial growth. The effects of sodium benzoate preservative on micronucleus induction, chromosome break, and Ala40Thr superoxide dismutase gene mutation in lymphocytes were studied.
Malinee Pongsavee
semanticscholar +2 more sources
Factors affecting the in vitro micronucleus assay for evaluation of nanomaterials [PDF]
Mutagenesis, 2017 Yan Li +8 more
semanticscholar +2 more sources
Chronic exposure effect study on Ramsar high background natural radiation areas (HBNRAs) residents using micronucleus assay [PDF]
مجله علوم و فنون هستهای, 2023 The effect of chronic exposure on Ramsar HBNRAs inhabitants' health was studied using Cytokinesis Blocked Micronucleus (CBMN) Assay. The results showed a significant difference (P
F. Abbasi Siar +3 more
doaj +1 more source
Micronucleus assay in cell phone users: Importance of oral mucosa screening
International Journal of Preventive Medicine, 2021 Background: One of the concerns of cell phone users is prolonged exposure to harmful and potentially carcinogenic waves. This study was aimed to investigate the correlation between amount of cell phone use and related factors with percentage of ...
Melika Ghandehari +2 more
doaj +1 more source
Genotoxicity of Di (2-ethyl hexyl) phthalate
Zhongguo shipin weisheng zazhi, 2022 ObjectiveTo assess the genotoxicity of Di（2-ethylhexyl） phthalate （DEHP）.MethodsA series of guideline-compliant assays were performed to evaluate mutagenicity， chromosomal or DNA damage of DEHP， including Ames test， in vitro mammalian chromosome ...
LI Juntao +9 more
doaj +1 more source
Automatic recognition of micronucleus by combining attention mechanism and AlexNet
BMC Medical Informatics and Decision Making, 2022 Background Micronucleus (MN) is an abnormal fragment in a human cell caused by disorders in the mechanism regulating chromosome segregation. It can be used as a biomarker for genotoxicity, tumor risk, and tumor malignancy. The in vitro micronucleus assay
Weiyi Wei +3 more
semanticscholar +1 more source
In vitro micronucleus assay: Method for assessment of nanomaterials using cytochalasin B
Frontiers in Toxicology, 2023 The in vitro micronucleus (MNvit) assay is used to evaluate the aneugenic and clastogenic potential of a test material based upon its ability to induce micronuclei in the cells.
Christopher S. Farabaugh +3 more
doaj +1 more source
Micronucleus Assay: The State of Art, and Future Directions
International Journal of Molecular Sciences, 2020 During almost 40 years of use, the micronucleus assay (MN) has become one of the most popular methods to assess genotoxicity of different chemical and physical factors, including ionizing radiation-induced DNA damage.
S. Sommer, I. Buraczewska, M. Kruszewski
semanticscholar +1 more source