Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro [PDF]
, 2013 This article is made available through the Brunel Open Access Publishing Fund. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/), which
Aardema +50 more
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Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes [PDF]
, 2014 The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present
Barrón-Vivanco, Briscia S. +9 more
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Journal of Health Sciences, 2013 Introduction: This study was performed to establish a baseline value of micronucleus frequency in buccal cells and to estimate the impact of the most common factors (sex and age, and smoking) on micronucleus and degenerative nuclear alteration ...
Hilada Nefić +4 more
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Protective effects of acerola juice on genotoxicity induced by iron in vivo
Genetics and Molecular Biology, 2016 Metal ions such as iron can induce DNA damage by inducing reactive oxygen species (ROS) and oxidative stress. Vitamin C is one of the most widely consumed antioxidants worldwide, present in many fruits and vegetables, especially inMalpighia glabra L ...
Roberta Nunes Horta +7 more
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The coordination of nuclear envelope assembly and chromosome segregation in metazoans
Nucleus, 2020 The nuclear envelope (NE) is composed of two lipid bilayer membranes that enclose the eukaryotic genome. In interphase, the NE is perforated by thousands of nuclear pore complexes (NPCs), which allow transport in and out of the nucleus. During mitosis in
Shiwei Liu, David Pellman
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Genotoxicity assessment of piperitenone oxide: an in vitro and in silico evaluation [PDF]
, 2017 Piperitenone oxide, a natural flavouring agent also known as rotundifolone, has been studied for the genotoxicity assessment by an integrated in vitro and in silico experimental approach, including the bacterial reverse mutation assay, the micronucleus ...
Abete, Lorena +9 more
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Association between human papillomavirus (HPV) DNA and micronuclei in normal cervical cytology [PDF]
Genetics and Molecular Biology, 2014 The aim of the present study was to investigate the association between HPV-DNA and micronucleus (MN) frequency in women with normal cervical cytology. A total of 158 normal cervical smears were analyzed cytologically.
Ana Paula Rebelo Cassel +4 more
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Estrogens and genomic instability in human cancer cells-involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals [PDF]
, 2008 This article is available open access through the publisher’s website. Copyright @ 2008 The Authors.Reports of the ability of estrogenic agents such as 17β-estradiol (E2), estriol (E3) and bisphenol A (BPA) to induce micronuclei (MN) in MCF-7 breast ...
A. Kabil +44 more
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Nanomaterials, 2020 The contamination of freshwaters by heavy metals represents a great problem, posing a threat for human and environmental health. Cadmium is classified as carcinogen to humans and its mechanism of carcinogenicity includes genotoxic events. In this study a
Patrizia Guidi +9 more
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In Vitro Mutagenic and Genotoxic Assessment of a Mixture of the Cyanotoxins Microcystin-LR and Cylindrospermopsin [PDF]
, 2019 The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different than those observed for single cyanotoxins, as interaction phenomena cannot be discarded. Moreover, mixtures are a more probable exposure scenario. However,
Cameán Fernández, Ana María +4 more
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