Results 71 to 80 of about 13,726,259 (365)

Toxicology evaluation of selenium protein powder

BIO Web of Conferences, 2017
The experiment was conducted to evaluate the safety of selenium protein powder, a novel organic selenium nutritional supplement, and reported corresponding data and results based on a series of toxicological tests.
Qin Shunyi, Liu Lina, Wang Jingshen, Zhao Fanghong, Ma Jifei   +4 more
doaj   +1 more source

Protective effects of acerola juice on genotoxicity induced by iron in vivo

Genetics and Molecular Biology, 2016
Metal ions such as iron can induce DNA damage by inducing reactive oxygen species (ROS) and oxidative stress. Vitamin C is one of the most widely consumed antioxidants worldwide, present in many fruits and vegetables, especially inMalpighia glabra L ...
Roberta Nunes Horta, Vivian Francilia Silva Kahl, Merielen da Silva Sarmento, Marisa Fernanda Silva Nunes, Carem Rejane Maglione Porto, Vanessa Moraes de Andrade, Alexandre de Barros Falcão Ferraz, Juliana Da Silva   +7 more
doaj   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Genotoxicity and Cytotoxicity Exerted by Pesticides in Different Biotic Matrices-An Overview of More Than a Decade of Experimental Evaluation [PDF]

, 2014
Agrochemicals represent one of the most important sources of environmental pollution. Although attempts to reduce agrochemical use through organic agricultural practices and the use of other technologies to control pests continue, the problem is still
Larramendy, Marcelo Luis, Nikoloff, Noelia, Ruiz de Arcaute, Celeste, Soloneski, Sonia Maria Elsa   +3 more
core   +2 more sources

Analysis of micronuclei in buccal epithelial cells in patients subjected to panoramic radiography

Indian Journal of Dental Research, 2012
Context: Ionizing radiation is a well-known carcinogen in humans. Chromosomal aberrations and formation of micronuclei in cell cytoplasm are early biological evidence of carcinogenesis.
Manjushri Waingade, Raghavendra S Medikeri   +1 more
doaj   +1 more source

Cytogenotoxicity of Abattoir Effluent in Clarias gariepinus (Burchell, 1822) Using Micronucleus Test

, 2015
The cytogenotoxic potential of abattoir effluent from Bodija, Nigeria, was investigated using micronucleus test in Clarias gariepinus. Fish was exposed to five different concentrations: 0.2, 0.4, 0.8, 1.6, and 3.1% of the effluent for 7, 14, and 28 days.
C. Alimba, E. Ajayi, T. Hassan, A. Sowunmi, A. Bakare   +4 more
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

New direct contact approach to evaluate soil genotoxicity using the Vicia faba micronucleus test. [PDF]

, 2009
A method to assess micronucleus (MN) induction in Vicia faba roots by direct contact exposure to a solid matrix was developed. The procedure comprised a 5-d germination period, as in the well-known method using aqueous extracts.
Cecchi, Marie, Cotelle, Sylvie, Guiresse, Agnès Maritchù, Marcato, Claire-Emmanuelle, Pinelli, Eric   +4 more
core   +3 more sources

In Vivo rodent micronucleus assay of Gmelina Arborea Roxb (Gambhari) extract

Journal of Advanced Pharmaceutical Technology & Research, 2010
Gmelina arborea Roxb (family Verbenaceae) commonly known as ′Gambhari′ tree, the various parts of the plants are widely used in diarrhoea, anti-pyretic, thirst, anemia, leprosy, ulcers, consumption, strangury, vaginal discharges.
Rohit Sahu, Goli Divakar, Kalyani Divakar   +2 more
doaj   +2 more sources

Clastogenicity of Piper cubeba (Piperaceae) seed extract in an in vivo mammalian cell system

Genetics and Molecular Biology, 2007
The plant Piper cubeba is widely distributed in tropical and subtropical regions and is used medically for various purposes but has not yet been evaluated for genotoxicity.
Adriana Pereira Freire Junqueira, Fabio Ferreira Perazzo, Gustavo Henrique Bianco Souza, Edson Luis Maistro   +3 more
doaj   +1 more source