Results 101 to 110 of about 15,524 (254)

Study of acute and subacute toxicities and genotoxic and mutagenic potentials of the lyophilized extract of Campomanesia sessiliflora (O.Berg) mattos leaves in wistar rats

Bioscience Journal
Campomanesia sessiliflora (O.Berg) Mattos is a Brazilian native plant species used in a popular medicinal tea for treating gastrointestinal, urinary, and dermatological pathologies.
Anahy Arruda Burigato, Jacenir Vieira da Silva, Larissa Pires Mueller, Flávio Henrique Souza de Araújo, Cláudia Andréa Lima Cardoso, Roosevelt Isaías Carvalho Souza, Agruslávia Rezende de Souza, Felipe Francisco Bittencourt Junior, Silvia Aparecida Oesterreich   +8 more
doaj   +1 more source

Safety assessment of the mixture of methyl-branched and linear C14–C18 alkanamides, derived from fatty acids, for use in food contact materials [PDF]

, 2017
Publisher ...
Barthélemy, Eric, Bolognesi, Claudia, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, Engel, Karl-Heinz, Fowler , Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kolf-Clauw, Martine, Kärenlampi, Sirpa, Lampi, Eugenia, Mennes, Wim, Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Svensson, Kettil, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +24 more
core   +3 more sources

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

Photochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye, Debra R. Garvey, Gagan Chhabra, Chandra K. Singh, Minakshi Nihal, Nihal Ahmad   +5 more
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Canine Urothelial DNA Mutations Are Not Associated With Total Trihalomethanes Concentrations in Municipal Drinking Water

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Contaminants in municipal drinking water, specifically total trihalomethanes (TTHMs), are mutagenic. Exposures to TTHMs have been associated with urothelial carcinoma (UC) in both people and dogs. Mutations in the BRAF gene and other genomic copy number aberrations detected in voided urothelial cells with commercial CADET BRAF and BRAF‐PLUS ...
Janice O'Brien, Samantha L. Braman, Jennifer Willcox, Phillip Wang, Daniel Gerrity, Audrey Ruple, Lauren A. Trepanier   +6 more
wiley   +1 more source

¿Influye la ozonoterapia sobre la médula ósea de ratones tratados?

Revista Cubana de Investigaciones Biomédicas
Se realizó el estudio de la actividad genotóxica del oleozón, mediante el ensayo de micronúcleos en médula ósea, en ratones de la línea Cenp:NMRI de uno y otro sexos; este ensayo constituye una determinación indirecta de la inducción de aberraciones ...
Antonia Remigio Montero, Yousy González Carvajal, Zullyt Zamora Rodríguez, Gladys Fonseca López   +3 more
doaj  

The Potential of Walnut Seeds (Canarium indicum L.) in Repairing The Genotoxicity Effect of Mercury on Mice Erythrocytes

Borneo Journal of Pharmacy, 2019
Hydrargyrum (familiar as mercury) is a persistent transition metal element. They are known as bio-accumulative properties that are dangerous to the environment and has serious damaging effects on biota, including genetic changes or mutagenesis. Moreover,
Cakra Haryo Wibowo, Essy Oktarina, Rafika Destiana Wardani, Khoirul Ngibad   +3 more
doaj   +1 more source

Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]

, 2018
Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
core   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Application of micronucleus assay in plants to monitor environmental pollution in situ [PDF]

, 2008
Samples of 5 vascular plant species: Achillea millefolium L., Artemisia vulgaris L., Festuca gigantea (L.) VILL., Ranunculus acris L. s. str. and Vicia angustifolia L. were collected near Fuel Storage Station, Chemical Fibre Factory “Wistom” in Tomaszów
Kośmider, Beata, Osiecka, Regina, Siciński, Jan T.   +2 more
core