Results 141 to 150 of about 195,958 (227)

Diarylpropionitrile inhibits melanogenesis via protein kinase A/cAMP-response element-binding protein/microphthalmia-associated transcription factor signaling pathway in α-MSH-stimulated B16F10 melanoma cells. [PDF]

Korean J Physiol Pharmacol, 2022
Lee HJ, An S, Bae S, Lee JH.
europepmc   +1 more source

Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance. [PDF]

, 2019
The oncoprotein transcription factor MYC is overexpressed in the majority of cancers. Key to its oncogenic activity is the ability of MYC to regulate gene expression patterns that drive and maintain the malignant state. MYC is also considered a validated
Adams, Clare M., Creighton, Joy, Eischen, Christine M., Fesik, Stephen W., Liu, Qi, Lorey, Shelly L., Tansey, William P., Thomas, Lance R., Wang, Jing, Weissmiller, April M.   +9 more
core   +1 more source

α-Mangostin, a safe and natural product as a candidate skin-whitening agent

Scientific Reports
A-Mangostin is the predominant xanthone found in the pericarp of mangosteen. It has been scientifically proven to possess anti-proliferative and apoptotic properties against different types of human cancer cells.
Xinmei Li, Xinyu Zhu, Bingqian Wang, Jiaming Sun, Yun Xia   +4 more
doaj   +1 more source

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. [PDF]

, 2017
PurposeThe RPE cell line ARPE-19 provides a dependable and widely used alternative to native RPE. However, replication of the native RPE phenotype becomes more difficult because these cells lose their specialized phenotype after multiple passages ...
Duncan, Todd, Jaworski, Cynthia, Kutty, R Krishnan, Lakkaraju, Aparna, Poliakov, Eugenia, Postnikova, Olga A, Redmond, T Michael, Samuel, William, Tan, Li Xuan   +8 more
core   +2 more sources

Correction: Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells. [PDF]

J Immunother Cancer, 2023
europepmc   +1 more source

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology.

Laboratory investigation; a journal of technical methods and pathology, 2017
A. Kawakami, D. Fisher
semanticscholar   +1 more source

529 Microphthalmia-associated transcription factor regulates dynamic melanoma heterogeneity [PDF]

Journal of Investigative Dermatology, 2017
N.K. Haass, L. Spoerri, C.A. Tonnessen, K.A. Beaumont, D.S. Hill, R.J. Jurek, S.M. Daignault, F. Ahmed, A.G. Smith, W. Weninger   +9 more
openaire   +1 more source

Microphthalmia-Associated Transcription Factor-Dependent Melanoma Cell Adhesion Molecule Activation Promotes Peritoneal Metastasis of Ovarian Cancer. [PDF]

Int J Mol Sci, 2020
Kitami K, Yoshihara M, Koya Y, Sugiyama M, Iyoshi S, Uno K, Mogi K, Tano S, Fujimoto H, Nawa A, Kikkawa F, Kajiyama H.   +11 more
europepmc   +1 more source

Role of retinoid mediated microphthalmia-associated transcription factor (MITF) in melanoma

International Journal of Medicine and Medical Sciences, 2012
Retinoic acid is the most effective therapeutic drug for the treatment of many types of cancer, including melanoma. All-trans retinoic acid (ATRA) increases the protein level of MITF in melanoma cells within 2 to 4 days (Chan, 2007), indicating that RA induced MITF plays a vital role in its anti-proliferative action. On the contrary, MITF silencing can
openaire   +1 more source

Anti-Melanogenic Effects of Cnidium monnieri Extract via p38 Signaling-Mediated Proteasomal Degradation of Tyrosinase

Plants
Cnidium monnieri fructus is widely used in traditional Oriental medicine for treating female genital disorders, male impotence, frigidity, and skin-related conditions in East Asia. However, the role of C.
Soon Ho Choi, Hyunggun Kim, Jeon Hwang-Bo, Kyoung Mi Kim, Jeong Eun Kwon, Sung Ryul Lee, Sun Ha Hwang, Se Chan Kang, Yeong-Geun Lee   +8 more
doaj   +1 more source