Microphthalmia-associated transcription factor mutations are associated with white-spotted coat color in swamp buffalo. [PDF]
Anim Genet, 2015 Summary A candidate gene analysis of the microphthalmia‐associated transcription factor (MITF) gene was used in an attempt to identify the genetic basis for a white‐spotted coat color phenotype in the Asian swamp buffalo (Bubalus bubalis carabanensis ...
Yusnizar Y +7 more
europepmc +2 more sources
C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation. [PDF]
PLoS ONE, 2011 The development of melanocytes is regulated by the tyrosine kinase receptor c-KIT and the basic-helix-loop-helix-leucine zipper transcription factor Mitf.
Bengt Phung +4 more
doaj +2 more sources
Regulatory and Functional Connection of Microphthalmia-Associated Transcription Factor and Anti-Metastatic Pigment Epithelium Derived Factor in Melanoma [PDF]
Neoplasia: An International Journal for Oncology Research, 2014 Pigment epithelium-derived factor (PEDF), a member of the serine protease inhibitor superfamily, has potent anti-metastatic effects in cutaneous melanoma through its direct actions on endothelial and melanoma cells.
Asunción Fernández-Barral +17 more
doaj +2 more sources
The roles of microphthalmia-associated transcription factor and pigmentation in melanoma. [PDF]
Arch Biochem Biophys, 2014 MITF and pigmentation play important roles in both normal melanocyte and transformed melanoma cell biology. MITF is regulated by many pathways and it also regulates many targets, some of which are still being discovered and functionally validated. MITF is involved in a wide range of processes in melanocytes, including pigment synthesis and lineage ...
Hsiao JJ, Fisher DE.
europepmc +4 more sources
A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression. [PDF]
Am J Pathol, 2015 Microphthalmia-associated transcription factor (MITF) acts via pigment epithelium-derived factor (PEDF), an antiangiogenic protein, to regulate retinal pigment epithelium migration.
Dadras SS +12 more
europepmc +2 more sources
MicroRNA-218 inhibits melanogenesis by directly suppressing microphthalmia-associated transcription factor expression. [PDF]
RNA Biol, 2014 The microphthalmia-associated transcription factor (MITF) is a pivotal regulator of melanogenic enzymes for melanogenesis, and its expression is modulated by many transcriptional factors at the transcriptional level or post-transcriptional level through microRNAs (miRNAs). Although several miRNAs modulate melanogenic activities, there is no evidence of
Guo J +7 more
europepmc +4 more sources
Microphthalmia-Associated Transcription Factor [PDF]
Definitions, 2020 semanticscholar +2 more sources
Betaine reduces cellular melanin content via suppression of microphthalmia-associated transcription factor in B16-F1 murine melanocytes. [PDF]
Food Sci Biotechnol, 2017 Cho BR, Jun HJ, Thach TT, Wu C, Lee SJ.
europepmc +2 more sources
Inhibition of oncogenic BRAF activity by indole-3-carbinol disrupts microphthalmia-associated transcription factor expression and arrests melanoma cell proliferation. [PDF]
Mol Carcinog, 2017 Kundu A +3 more
europepmc +2 more sources
Transcription factor E3 renal cell carcinoma presenting as secondary hypertension
Current Urology, 2023 . Microphthalmia-associated transcription factor family (transcription factor E3 or transcription factor EB) translocation renal cell carcinomas (RCCs) are rare neoplasms.
Alain Mwamba Mukendi +3 more
doaj +1 more source