Results 41 to 50 of about 195,958 (227)

Otx but Not Mitf Transcription Factors Are Required for Zebrafish Retinal Pigment Epithelium Development [PDF]

open access: yes, 2012
Otx and Mitf transcription factors have been implicated in the development of the retinal pigmented epithelium (RPE), but the relationship between these factors and their specific roles in the development of the RPE have not been fully defined.
Lane, Brandon M., Lister, James A.
core   +13 more sources

Inhibitory Effects of Cycloheterophyllin on Melanin Synthesis

open access: yesMolecules, 2021
This study was performed to clarify the inhibitory effects of cycloheterophyllin on melanin synthesis. In order to elucidate the inhibitory effects of cycloheterophyllin on the B16F10 cell line, cell viability, messenger ribonucleic acid (mRNA ...
Joong-Hyun Shim
doaj   +1 more source

Ginsenoside Re inhibits melanogenesis and melanoma growth by downregulating microphthalmia-associated transcription factor.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Panax ginseng, also known as Korean ginseng, is a traditional remedy widely used in Asian countries. Its major active compounds are ginsenosides, specifically triterpenoid saponins.
S. Hwang, Hye Jung Bang, Hyo-Jong Lee
semanticscholar   +1 more source

The Oncogene Transcription Factor EB Regulates Vascular Functions

open access: yesFrontiers in Physiology, 2021
Transcription factor EB (TFEB) represents an emerging player in vascular biology. It belongs to the bHLH-leucine zipper transcription factor microphthalmia family, which includes microphthalmia-associated transcription factor, transcription factor E3 and
Gabriella Doronzo   +5 more
doaj   +1 more source

The Biochemical and Molecular Analysis of Changes in Melanogenesis Induced by UVA-Activated Fluoroquinolones—In Vitro Study on Human Normal Melanocytes

open access: yesCells, 2021
Fluoroquinolones cause phototoxic reactions, manifested as different types of skin lesions, including hyperpigmentation. The disturbances of melanogenesis indicate that fluoroquinolones may affect cellular processes in melanocytes.
Justyna Kowalska   +5 more
doaj   +1 more source

Molecular Mechanisms of Anti-Melanogenic Gedunin Derived from Neem Tree (Azadirachta indica) Using B16F10 Mouse Melanoma Cells and Early-Stage Zebrafish

open access: yesPlants, 2021
Melanogenesis represents a series of processes that produce melanin, a protective skin pigment (against ultraviolet rays), and determines human skin color. Chemicals reducing melanin production have always been in demand in the cosmetic market because of
Hwang-Ju Jeon   +5 more
doaj   +1 more source

MITF (microphthalmia-associated transcription factor) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on MITF (microphthalmia-associated transcription factor), with data on DNA, on the protein encoded, and where the gene is implicated.
Riddle, ND, Zhang, P
openaire   +2 more sources

MD investigation on the binding of microphthalmia-associated transcription factor with DNA

open access: yesJournal of Saudi Chemical Society, 2022
As a main regulator of melanocyte development and an key melanoma oncogene, microphthalmia-associated transcription factor (MITF) is one of the proteins in the basic helix-loop-helix zipper (bHLHZip) transcription factor family. The study on the detailed
Xiang-Feng Wang   +6 more
doaj   +1 more source

Fraxinol Stimulates Melanogenesis in B16F10 Mouse Melanoma Cells through CREB/MITF Signaling

open access: yesMolecules, 2022
Melanin pigment produced in melanocytes plays a protective role against ultraviolet radiation. Selective destruction of melanocytes causes chronic depigmentation conditions such as vitiligo, for which there are very few specific medical treatments. Here,
Sun Young Moon   +7 more
doaj   +1 more source

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