Spatiotemporal 22q11.21 Protein Network Implicates DGCR8-Dependent MicroRNA Biogenesis as a Risk for Late-Fetal Cortical Development in Psychiatric Diseases. [PDF]
Chen L, Cai W, Wang W, Liu Z, Lin GN.
europepmc +1 more source
Metabolic Dysfunction‐Associated Fatty Liver Disease: From Pathogenesis to Treatment
Extracellular vesicles play a crucial role in interorgan crosstalk of adipose–liver and gut–liver axes and hold potential as therapeutic targets and drug delivery systems for metabolic dysfunction‐associated fatty liver disease (MAFLD). Abbreviations: AT: adipose tissue; EVs: extracellular vesicles; HL: healthy liver; NAFL: nonalcoholic fatty liver ...
Zhifu Cui +5 more
wiley +1 more source
MicroRNA biogenesis is broadly disrupted by inhibition of the splicing factor SF3B1. [PDF]
Downie Ruiz Velasco A +6 more
europepmc +1 more source
Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus +5 more
wiley +1 more source
Identification of <i>Cr</i>DCL1-mediated microRNA biogenesis in green alga <i>Chlamydomonas reinhardtii</i>. [PDF]
Sun T, Tao M, Di Q, Hu Z, Li H, Lou S.
europepmc +1 more source
Complexity in regulating microRNA biogenesis in cancer. [PDF]
Chen PS, Lin SC, Tsai SJ.
europepmc +1 more source
Cucumber green mottle mosaic virus: A persistent seed‐borne threat to cucurbits
Cucumber green mottle mosaic virus (CGMMV) is a highly stable, seed‐borne tobamovirus that threatens global cucurbit production. Its efficient mechanical and seed transmission, long‐term environmental persistence, and the spread of Clade II CGMMV isolates drive its rapid dissemination and cause severe yield losses.
Esperanza Gea‐Caballero +1 more
wiley +1 more source
tRNA, yRNA, and rRNA fragment excisions do not involve canonical microRNA biogenesis machinery. [PDF]
Godang NL +9 more
europepmc +1 more source
Identification of key sequence features required for microRNA biogenesis in plants. [PDF]
Rojas AML +10 more
europepmc +1 more source
This review systematically elucidates the multifactorial anti‐aging mechanisms of extracellular vesicles (EVs). By bridging fundamental biology with advanced bioengineering, scalable manufacturing, and clinical translation, it establishes a comprehensive framework for developing next‐generation EVs‐based precision nanotherapeutics to combat systemic ...
Xian Huang +6 more
wiley +1 more source

