Results 161 to 170 of about 31,660 (233)

Identification of key sequence features required for microRNA biogenesis in plants. [PDF]

Nat Commun, 2020
Rojas AML, Drusin SI, Chorostecki U, Mateos JL, Moro B, Bologna NG, Bresso EG, Schapire A, Rasia RM, Moreno DM, Palatnik JF.   +10 more
europepmc   +1 more source

MIR194-2HG, a miRNA host gene activated by HNF4A, inhibits gastric cancer by regulating microRNA biogenesis. [PDF]

Biol Direct
Cao H, Wang Z, Guo Q, Qin S, Li D.
europepmc   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, Volume 13, Issue 16, 18 August 2026.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Evolution of MicroRNA Biogenesis Genes in the Sterlet (Acipenser ruthenus) and Other Polyploid Vertebrates. [PDF]

Int J Mol Sci, 2020
Fofanov MV, Prokopov DY, Kuhl H, Schartl M, Trifonov VA.   +4 more
europepmc   +1 more source

G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation

Advanced Science, Volume 13, Issue 45, 13 August 2026.
G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang, Qingqing Xu, Yuxin Zhang, Fang Liu, Guangchao Sui, Dangdang Li   +5 more
wiley   +1 more source

The METHYLTRANSFERASE B-SERRATE interaction mediates the reciprocal regulation of microRNA biogenesis and RNA m⁶A modification. [PDF]

J Integr Plant Biol
Bai H, Dai Y, Fan P, Zhou Y, Wang X, Chen J, Jiao Y, Du C, Huang Z, Xie Y, Guo X, Lang X, Ling Y, Deng Y, Liu Q, He S, Zhang Z.   +16 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles

BioEssays, Volume 48, Issue 8, August 2026.
Mitotic cells produce three EV types: exosomes and microvesicles (green/blue) delivering pre‐formed molecules, and midbody remnants (magenta) containing functional ribosomes and translation machinery within biomolecular condensates. Unlike passive cargo carriers, MBRs actively synthesize proteins after release, transforming from cellular debris to ...
Ahna R. Skop
wiley   +1 more source

MicroRNAs in Spinal Cord Injury: Molecular and Translational Insights

Brain and Behavior, Volume 16, Issue 8, August 2026.
MicroRNAs (miRNAs) modulate secondary injury cascades following spinal cord injury (SCI), including inflammation, oxidative stress, apoptosis, and demyelination. Key miRNAs such as miR‐21, miR‐124, miR‐219, and miR‐223 exert neuroprotective effects by regulating astrocytic response, axon regeneration, and remyelination.
Seyyedeh Fahimeh Talebi, Hossein Kalarestaghi, Ehsan Sheikh Hesabi, Saeed Vafaei‐Nezhad   +3 more
wiley   +1 more source

Widespread transcriptional disruption of the microRNA biogenesis machinery in brain and peripheral tissues of individuals with schizophrenia. [PDF]

Transl Psychiatry, 2020
Rey R, Suaud-Chagny MF, Dorey JM, Teyssier JR, d'Amato T.   +4 more
europepmc   +1 more source