Results 151 to 160 of about 55,423 (289)

Mutations in Components of the TREX‐2 Complex Result in Misexpression of the Kelch‐Domain F‐Box Protein KFB39 Promoter in Arabidopsis thaliana

Plant Direct, Volume 10, Issue 2, February 2026.
ABSTRACT Arabidopsis thaliana gene At2g44130 encodes a Kelch‐like domain F‐box protein designated KFB39 and was previously shown to be specifically expressed on exposure to the oxylipin cis‐jasmone. In order to better understand the regulation of At2g44130, a forward genetic screen was carried out to identify mutants in which a promoter‐GUS fusion was ...
Michaela C. Matthes, Smita Kurup, John A. Pickett, Johnathan A. Napier   +3 more
wiley   +1 more source

The Role of Microsatellite Instability in Endometrial Hyperplasia and Risk of Carcinoma Development. [PDF]

Biomedicines
Mollova-Kyosebekirova A, Uchikova E, Mihaylova A, Koleva-Ivanova M, Parahuleva M, Parahuleva N.   +5 more
europepmc   +1 more source

Detection of Microsatellite Instability in Endometrial Carcinoma Using a Novel Homopolymer Assay [PDF]

Catherine M. Nicka, Donald C. Green, Gregory J. Tsongalis, Laura J. Tafe   +3 more
openalex   +1 more source

Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies

Clinical Genetics, Volume 109, Issue 2, Page 305-315, February 2026.
Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome. ABSTRACT Ciliopathies are rare genetic disorders characterized by significant genetic and phenotypic variability.
Lucile Boutaud, Chunmei Li, Candice Moncler, Laure Verlin, Meriem Garfa‐Traoré, Nicolas Bourgon, Dhruvin Akbari, Jeanne Porée, Valentina Serpieri, Marine Panza, Lynda Haddad, Patrick Nitschké, Jacqueline Aziza, Cristina Matt, Enza Maria Valente, Patricia Gargallo, Charlotte Dubucs, Tania Attié‐Bitach, Michel R. Leroux, Sophie Thomas   +19 more
wiley   +1 more source

Improving the performance of polymerase chain reaction for microsatellite instability testing in endometrial cancer. [PDF]

Sci Rep
Mendiola M, Heredia-Soto V, Baillo A, Ruz-Caracuel I, Mena R, Berjón A, Escudero FJ, Pedregosa J, Hernandez A, Feliu J, Hardisson D, Redondo A.   +11 more
europepmc   +1 more source

Additional file 2 of Characterization of metabolic responses, genetic variations, and microsatellite instability in ammonia-stressed CHO cells grown in fed-batch cultures

, 2021
Dylan G. Chitwood, Qinghua Wang, Kathryn Elliott, Aiyana Bullock, Dwon Jordana, Zhigang Li, Cathy Wu, Sarah W. Harcum, Christopher Saski   +8 more
openalex   +1 more source

Blurring the Lines: Co‐Occurrence of MSH6 Variant and MLH1 Constitutional Epimutation in a Young Colorectal Cancer Patient

Clinical Genetics, Volume 109, Issue 2, Page 363-367, February 2026.
We report a unique case of early‐onset colorectal cancer with both a germline MSH6 variant and constitutional mosaic MLH1 epimutation, revealing a possible digenic mechanism underlying Lynch syndrome. This case highlights the diagnostic complexity of mismatch repair deficiency and the value of integrative tumor–germline molecular profiling.
Aasem Abu Shtaya, Yarin Hadid, Ahmad Mahamid, Debora Kidron, Naama Halpern, Adel Shalata, Zohar Levi, Yael Goldberg   +7 more
wiley   +1 more source

Diagnostic Challenges and Clinical Implications of Microsatellite Instability/Mismatch Repair Deficiency in Solid Tumors. [PDF]

Cancer Res Treat
Kwak Y, Bae JM, Lee HS.
europepmc   +1 more source

Genetic origins and climate‐induced erosion in economically important Asian walnuts

Conservation Biology, Volume 40, Issue 1, February 2026.
Abstract The global climate is undergoing unprecedented changes, posing significant threats to species persistence. However, the spatiotemporal impacts on genetic diversity remain poorly understood, hindering species conservation and management. Walnuts, generally referred to as Juglans regia and J. sigillata, are economically vital in Asia, but little
Peng‐Zhen Fan, Guang‐Fu Zhu, Moses C. Wambulwa, Richard I. Milne, Zeng‐Yuan Wu, Ya‐Huang Luo, Robabeh Shahi Shavvon, Alistair S. Jump, Debabrata Maity, Lian‐Ming Gao, Hai‐Ling Qi, Hong‐Yu Wu, Xing Kong, Raees Khan, Li‐Jun Yan, Yerlan Turuspekov, De‐Zhu Li, Jie Liu   +17 more
wiley   +1 more source

<i>Bacteroides fragilis</i> toxin in colorectal tumors activates STAT3 and drives microsatellite instability. [PDF]

Ann Med Surg (Lond)
Mehmood MS, Danaf N.
europepmc   +1 more source