Results 61 to 70 of about 48,754 (308)

Development of 201 tri- and tetra-nucleotide repeat microsatellites for bighead carp (Aristichthys nobilis)

, 2013
In this study we developed 201 tri- and tetra-nucleotide repeat microsatellites for bighead carp (Aristichthys nobilis), and 135 of them showed polymorphism.
Tong, Jingou, Zhu, Chuankun, Fu, B., Yu, Xiaomu, Tong, JG (reprint author), Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Peoples R China.   +4 more
core   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Breaking the Diffraction Barrier: A Hybrid Framework Combining Physical Modulation and Neural Diffusion for Subdiffraction Target Recovery

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Although most aircraft are equipped with active communication systems, such as ADS-B and satellite links, these systems may fail in emergencies or when signals are lost. At this point, remote sensing, as a passive observation method that does not require
Xuening Liu, Zengshan Yin, Chongbin Guo, Changhao Wu   +3 more
doaj   +1 more source

Distribution of microsatellites around promoters.

, 2013
The total number of microsatellites present in each 100 base-pair bin are provided for all microsatellites within 10 kb of the TSS. Also shown are the total number of only coding microsatellites (blue) or only 5′ UTR microsatellites (red).
Pankaj Kumar (63234), Michael A. Black (154620), Andrew Bagshaw (279710), Emmanuel Buschiazzo (190453), Neil Gemmell (279711), Sterling Sawaya (279709), Shantanu Chowdhury (8248)   +6 more
core   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

nuclear microsatellites

, 2019
Nuclear microsatellites RAW data ...
Andrew Cunningham (601959), Stefan de Vries (7063664), Cunningham, Andrew, Wood, James, Richard Suu-Ire (343682), de Vries, Stefan, Sargan, David, Suu-Ire, Richard, David Sargan (7063688), Amponsah-Mensah, Kofi, Kofi Amponsah-Mensah (6594617), Aude Lalis (164592), Nicolas, Violaine, Riesle-Sbarbaro, Silke, Silke Riesle-Sbarbaro (7063667), Lalis, Aude, James Wood (325505), Violaine Nicolas (119305)   +17 more
core   +1 more source

CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors

Advanced Science, EarlyView.
Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen, Xiaoyun Luo, Huixin Gao, Yujing Ke, Yu Zhan, Xiaoting Xu, Xiaoxiao Xiong, Fengjiao Wei, Si Yang, Zhonghua Liu, Bolan Yu, Zhaofeng Huang, Yingjie Bian   +12 more
wiley   +1 more source

Optimization of Test Mass Motion State for Enhancing Stiffness Identification Performance in Space Gravitational Wave Detection

Aerospace
In space gravitational wave detection, various physical effects in the spacecraft, such as self-gravity, electricity, and magnetism, will introduce undesirable parasitic stiffness.
Ningbiao Tang, Ziruo Fang, Zhongguang Yang, Zhiming Cai, Haiying Hu, Huawang Li   +5 more
doaj   +1 more source

Polymorphic microsatellites in largemouth bronze gudgeon (Coreius guichenoti) developed from repeat-enriched libraries and cross-species amplifications

, 2007
Largemouth bronze gudgeon (Coreius guichenoti) is a medium-sized fish endemic from the upper Yangtze River of China and its survival is threatened by the construction of the Three Gorges Dam.
Yu, X., Tong, J., Chang, J., Liao, X., Tong, J, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China   +4 more
core   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source