Results 71 to 80 of about 86,640 (310)

Study of Free‐Space Optical Quantum Network: Review and Prospectives

open access: yesAdvanced Science, EarlyView.
Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.
Hua‐Ying Liu, Zhenda Xie, Shining Zhu
wiley   +1 more source

GHGPSE-Net: a method towards spaceborne automated extraction of greenhouse-gas point sources using point-object-detection deep neural network [PDF]

open access: yesGeoscientific Model Development
Point sources account for a large portion of anthropogenic greenhouse gas (GHG) emissions. Timely detection, localization, and quantification of these emissions are critical for supporting carbon neutrality efforts.
Y. Pang   +6 more
doaj   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Deep Learning-Based Digital Surface Model Reconstruction of ZY-3 Satellite Imagery

open access: yesRemote Sensing
This study introduces a novel satellite image digital surface model (DSM) reconstruction framework grounded in deep learning methodology. The proposed framework effectively utilizes a rational polynomial camera (RPC) model to establish the mapping ...
Yanbin Zhao   +5 more
doaj   +1 more source

Dynamic microsatellites in transcribed regions of gastropod mitochondrial 16S rDNA [PDF]

open access: yes, 2006
Length variations of repetitive sequences in different AT-rich loop-coding regions of mitochondrial 16S rDNA in two gastropod species were discovered during intraspecific haplotype surveys. Examination of the discrete length variation of the basic repeat
Bugert, Monika, Pfenninger, Markus
core  

Drift, not selection, shapes toll-like receptor variation among oceanic island populations [PDF]

open access: yes, 2015
Understanding the relative role of different evolutionary forces in shaping the level and distribution of functional genetic diversity among natural populations is a key issue in evolutionary and conservation biology.
Acevedo-Whitehouse   +78 more
core   +2 more sources

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

AFLPs: genetic markers for paternity studies in newts (Triturus vulgaris) [PDF]

open access: yes, 2006
DNA-based genetic markers can reveal paternity whenever the direct assignment of fathers to offspring is precluded by multiple matings and internal fertilisation.
Jehle, R, Sztatecsny, M, Whitlock, A
core   +2 more sources

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

open access: yesAdvanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo   +8 more
wiley   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao   +12 more
wiley   +1 more source

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