Results 111 to 120 of about 211,422 (165)

Microtubule oscillations. Role of nucleation and microtubule number concentration

, 1990
Microtubules are capable of performing synchronized oscillations of assembly and disassembly which has been explained by reaction mechanisms involving tubulin subunits, oligomers, microtubules, and GTP.
Lange, G., Obermann, H., Mandelkow, E. M., Mandelkow, E.   +3 more
core  

Microtubule nucleation by γ-tubulin complexes and beyond.

, 2018
In this short review, we give an overview of microtubule nucleation within cells. It is nearly 30 years since the discovery of γ-tubulin, a member of the tubulin superfamily essential for proper microtubule nucleation in all eukaryotes.

core   +2 more sources

Microtubule nucleation without a ring? [PDF]

J Cell Biol, 2021
Merdes A.
europepmc   +1 more source

Toward a molecular mechanism of branching microtubule nucleation

, 2020
The microtubule cytoskeleton supports cell function by giving cells their shape, organizing their interior and segregating chromosomes. Microtubules are nucleated from specific locations at precise times in the cell cycle.
Alfaro-Aco, Raymundo
core  

Microtubule nucleation complex behavior is critical for cortical array homogeneity and xylem wall patterning. [PDF]

Proc Natl Acad Sci U S A, 2022
Jacobs B, Schneider R, Molenaar J, Filion L, Deinum EE.   +4 more
europepmc   +1 more source

The γ-TuRC: mastermind of multipurpose actions at the centrosome

Cellular and Molecular Life Sciences
The γ-Tubulin Ring Complex (γ-TuRC) comprised of γ-tubulin and γ-tubulin complex proteins (GCP2-6) serves as the main protein scaffold for microtubule nucleation in most animal cells.
Swarnendu Mukhopadhyay, Qi Gao, Tapas K. Manna, Elmar Schiebel   +3 more
doaj   +1 more source

An alternative splice isoform of mouse CDK5RAP2 induced cytoplasmic microtubule nucleation. [PDF]

IBRO Neurosci Rep, 2022
Nakamura A, Ikeda M, Kusayanagi S, Hayashi K.   +3 more
europepmc   +1 more source

Tubacin alleviate the reproductive toxicity of deoxynivalenol in mouse oocytes and zygotes via strengthening microtubule stability

Cell Communication and Signaling
Deoxynivalenol (DON) is one of the most common food contaminants, widely present in grain products. Studies using murine and porcine models show deoxynivalenol exposure impairs oocyte maturation and mitochondrial function; however, the exact mechanisms ...
Hui Luo, Jianhua Chen, Zhihan Guo, Yanyan Zhu, Yipin Wang, Tian Wu, Siyue Yin, Cao Li, Youqiang Su, Yao Chen, Yun Qian, Congxiu Miao, Ruizhi Feng   +12 more
doaj   +1 more source

NEDD1-S411 phosphorylation plays a critical function in the coordination of microtubule nucleation during mitosis. [PDF]

Biol Open, 2022
Timón Pérez K, Scrofani J, Vernos I.
europepmc   +1 more source

Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1.

Curr Biol, 2023
Leong SL, Lynch EM, Zou J, Tay YD, Borek WE, Tuijtel MW, Rappsilber J, Sawin KE.   +7 more
europepmc   +1 more source