Results 121 to 130 of about 211,422 (165)

The centrosomal recruitment of γ-tubulin and its microtubule nucleation activity is α-fodrin guided. [PDF]

Cell Cycle, 2023
Sreeja JS, Jyothy A, Nellikka RK, Ghorai S, Riya PA, James J, Sengupta S.   +6 more
europepmc   +1 more source

Nme7 regulates microtubule nucleation by the γ-tubulin ring complex

, 2014
As the primary microtubule nucleator in animal cells, the γ-tubulin ring complex (γTuRC) plays a crucial role in microtubule organization, but little is known about how the activity of the γTuRC is regulated. Recently, isolated γTuRC was found to contain
Qi, Robert Zhong, Choi, Yukkwan, Liu, Pengfei   +2 more
core  

Structural Organization of the Augmin Complex Involved in Branching Microtubule Nucleation

, 2017
Microtubules are critical cellular structures involved in many processes of the eukaryotic cell, especially in cell division. They are built and organized by nucleation, polymerization and transport events involving a complex network of proteins in the ...
Erdenee, Elbegduuren
core  

CAMSAPs and nucleation-promoting factors control microtubule release from γ-TuRC [PDF]

γ-Tubulin ring complex (γ-TuRC) is the major microtubule-nucleating factor. After nucleation, microtubules can be released from γ-TuRC and stabilized by other proteins, such as CAMSAPs, but the biochemical cross-talk between minus-end regulation pathways
Yin, Victor, Heck, Albert J R, Katrukha, Eugene A, Song, Yinlong, Altelaar, Maarten, Monster, Jooske L, Xu, Yixin, Zhang, Yaqian, Wieczorek, Michal, Jiang, Kai, Chen, Fangrui, Stucchi, Riccardo, Stecker, Kelly, Akhmanova, Anna, Hua, Shasha, Rai, Dipti, Cell Biology, Neurobiology and Biophysics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Sub Cell Biology, Afd Biomol.Mass Spect. and Proteomics   +20 more
core   +2 more sources

The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC). [PDF]

Elife, 2022
Rale MJ, Romer B, Mahon BP, Travis SM, Petry S.   +4 more
europepmc   +1 more source

Terminally differentiated osteoclasts organize centrosomes into large clusters for microtubule nucleation and bone resorption. [PDF]

Mol Biol Cell, 2022
Philip R, Fiorino C, Harrison RE.
europepmc   +1 more source

Centriole and Golgi microtubule nucleation are dispensable for the migration of human neutrophil-like cells. [PDF]

Mol Biol Cell, 2021
Klemm LC, Denu RA, Hind LE, Rocha-Gregg BL, Burkard ME, Huttenlocher A.   +5 more
europepmc   +1 more source

Identification of a cytosol-to-nucleus feedback loop that regulates neuronal microtubule nucleation. [PDF]

J Cell Biol
Kumar N, Carey N, Hertzler JI, Bernard AR, Mahata G, Kothe GO, Shen Y, Rolls MM.   +7 more
europepmc   +1 more source

The Chromatin Protein CFDP1 Activates TPX2 and Promotes Chromosomal Microtubule Nucleation and Spindle Assembly. [PDF]

Int J Mol Sci
Gopinathan G, Luan X, Diekwisch TGH.
europepmc   +1 more source

GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation. [PDF]

J Cell Biol, 2021
Ayukawa R, Iwata S, Imai H, Kamimura S, Hayashi M, Ngo KX, Minoura I, Uchimura S, Makino T, Shirouzu M, Shigematsu H, Sekimoto K, Gigant B, Muto E.   +13 more
europepmc   +1 more source