Fibrous corona is reduced in cancer cell lines that attenuate microtubule nucleation from kinetochores. [PDF]
Cancer SciIshikawa Y +5 more
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CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation. [PDF]
Elife, 2021 Brilot AF +9 more
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MLL/WDR5 complex recruits centriolar satellite protein Cep72 to regulate microtubule nucleation and spindle formation. [PDF]
Sci AdvChodisetty S +4 more
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Structure of the microtubule nucleation sites
Microtubules (MTs) are part of cytoskeleton responsible for cell cargo trafficking, cell shape and cell division. Nucleation of microtubules occurs at specific cellular organelle called microtubule organizing centrum (MTOCs). As the mayor microtubule nucleator is consider g tubulin complexes (gTuC).
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Microtubule Nucleation and Stabilization by Doublecortin [PDF]
Biophysical Journal, 2019 Szymon W. Manka, Carolyn A. Moores
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Branched microtubule nucleation and dynein transport organize RanGTP asters in <i>Xenopus laevis</i> egg extract. [PDF]
Mol Biol CellScrofani J +6 more
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The cryo-EM structure of a γ-TuSC elucidates architecture and regulation of minimal microtubule nucleation systems. [PDF]
Nat Commun, 2020 Zupa E +7 more
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Microtubule nucleation promoters Mto1 and Mto2 regulate cytokinesis in fission yeast. [PDF]
Mol Biol Cell, 2020 Dundon SER, Pollard TD.
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Microtubule nucleation and dynamic instability in interphase fission yeast. [PDF]
J Mol Cell Biol, 2019 Liang X.
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