Results 1 to 10 of about 228,374 (345)
Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro. [PDF]
PLoS ONE, 2016 Microtubule structure and functions have been widely studied in vitro and in cells. Research has shown that cysteines on tubulin play a crucial role in the polymerization of microtubules.
Meenakshi Prabhune +3 more
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Quantitative mapping of dense microtubule arrays in mammalian neurons
eLife, 2021 The neuronal microtubule cytoskeleton underlies the polarization and proper functioning of neurons, amongst others by providing tracks for motor proteins that drive intracellular transport.
Eugene A Katrukha +3 more
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Scientific Reports, 2023 The physical properties of cytoskeletal microtubules have a multifaceted effect on the expression of their cellular functions. A superfamily of microtubule-associated proteins, MAP2, MAP4, and tau, promote the polymerization of microtubules, stabilize ...
Kohei Nishida +10 more
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Microtubules and Microtubule-Associated Proteins [PDF]
Cold Spring Harbor Perspectives in Biology, 2018 Microtubules act as "railways" for motor-driven intracellular transport, interact with accessory proteins to assemble into larger structures such as the mitotic spindle, and provide an organizational framework to the rest of the cell. Key to these functions is the fact that microtubules are "dynamic." As with actin, the polymer dynamics are driven by ...
Holly V. Goodson, Erin M. Jonasson
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Microtubules accelerate the kinase activity of Aurora-B by a reduction in dimensionality. [PDF]
PLoS ONE, 2014 Aurora-B is the kinase subunit of the Chromosome Passenger Complex (CPC), a key regulator of mitotic progression that corrects improper kinetochore attachments and establishes the spindle midzone.
Michael Noujaim +3 more
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Binding of Tau-derived peptide-fused GFP to plant microtubules in Arabidopsis thaliana.
PLoS ONE, 2023 Studies on how exogenous molecules modulate properties of plant microtubules, such as their stability, structure, and dynamics, are important for understanding and modulating microtubule functions in plants.
Hiroshi Inaba +5 more
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Actin–Microtubule Crosstalk Imparts Stiffness to the Contractile Ring in Fission Yeast
Cells, 2023 Actin–microtubule interactions are critical for cell division, yet how these networks of polymers mutually influence their mechanical properties and functions in live cells remains unknown.
Kimberly Bellingham-Johnstun +4 more
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Plant Direct, 2023 Although microtubules in plant cells have been extensively studied, the mechanisms that regulate the spatial organization of microtubules are poorly understood.
Mohammad Murshed +3 more
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Unrestrained growth of correctly oriented microtubules instructs axonal microtubule orientation
eLife, 2022 In many eukaryotic cells, directed molecular transport occurs along microtubules. Within neuronal axons, transport over vast distances particularly relies on uniformly oriented microtubules, whose plus-ends point towards the distal axon tip ...
Maximilian AH Jakobs +2 more
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Nanomechanics of Microtubules [PDF]
Physical Review Letters, 2002 We have determined the mechanical anisotropy of a single microtubule by simultaneously measuring the Young's and the shear moduli in vitro. This was achieved by elastically deforming the microtubule deposited on a substrate tailored by electron-beam lithography with a tip of an atomic force microscope.
B. Babić +9 more
openaire +4 more sources