Results 1 to 10 of about 106,557 (263)

Quantitative mapping of dense microtubule arrays in mammalian neurons

open access: yeseLife, 2021
The neuronal microtubule cytoskeleton underlies the polarization and proper functioning of neurons, amongst others by providing tracks for motor proteins that drive intracellular transport.
Eugene A Katrukha   +3 more
doaj   +1 more source

Effects of three microtubule-associated proteins (MAP2, MAP4, and Tau) on microtubules’ physical properties and neurite morphology

open access: yesScientific Reports, 2023
The physical properties of cytoskeletal microtubules have a multifaceted effect on the expression of their cellular functions. A superfamily of microtubule-associated proteins, MAP2, MAP4, and tau, promote the polymerization of microtubules, stabilize ...
Kohei Nishida   +10 more
doaj   +1 more source

Binding of Tau-derived peptide-fused GFP to plant microtubules in Arabidopsis thaliana.

open access: yesPLoS ONE, 2023
Studies on how exogenous molecules modulate properties of plant microtubules, such as their stability, structure, and dynamics, are important for understanding and modulating microtubule functions in plants.
Hiroshi Inaba   +5 more
doaj   +1 more source

Unrestrained growth of correctly oriented microtubules instructs axonal microtubule orientation

open access: yeseLife, 2022
In many eukaryotic cells, directed molecular transport occurs along microtubules. Within neuronal axons, transport over vast distances particularly relies on uniformly oriented microtubules, whose plus-ends point towards the distal axon tip ...
Maximilian AH Jakobs   +2 more
doaj   +1 more source

Microtubules accelerate the kinase activity of Aurora-B by a reduction in dimensionality. [PDF]

open access: yesPLoS ONE, 2014
Aurora-B is the kinase subunit of the Chromosome Passenger Complex (CPC), a key regulator of mitotic progression that corrects improper kinetochore attachments and establishes the spindle midzone.
Michael Noujaim   +3 more
doaj   +1 more source

Simulation of microtubule–cytoplasm interaction revealed the importance of fluid dynamics in determining the organization of microtubules

open access: yesPlant Direct, 2023
Although microtubules in plant cells have been extensively studied, the mechanisms that regulate the spatial organization of microtubules are poorly understood.
Mohammad Murshed   +3 more
doaj   +1 more source

Actin–Microtubule Crosstalk Imparts Stiffness to the Contractile Ring in Fission Yeast

open access: yesCells, 2023
Actin–microtubule interactions are critical for cell division, yet how these networks of polymers mutually influence their mechanical properties and functions in live cells remains unknown.
Kimberly Bellingham-Johnstun   +4 more
doaj   +1 more source

Investigation of the Electrical Properties of Microtubule Ensembles under Cell-Like Conditions

open access: yesNanomaterials, 2020
Microtubules are hollow cylindrical polymers composed of the highly negatively-charged (~23e), high dipole moment (1750 D) protein α, β- tubulin.
Aarat P. Kalra   +9 more
doaj   +1 more source

Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro. [PDF]

open access: yesPLoS ONE, 2016
Microtubule structure and functions have been widely studied in vitro and in cells. Research has shown that cysteines on tubulin play a crucial role in the polymerization of microtubules.
Meenakshi Prabhune   +3 more
doaj   +1 more source

Lab-on-chip microscope platform for electro-manipulation of a dense microtubules network

open access: yesScientific Reports, 2022
Pulsed electric field (PEF) technology is promising for the manipulation of biomolecular components and has potential applications in biomedicine and bionanotechnology.
Daniel Havelka   +5 more
doaj   +1 more source

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