Investigation of the Electrical Properties of Microtubule Ensembles under Cell-Like Conditions [PDF]
Nanomaterials, 2020 Microtubules are hollow cylindrical polymers composed of the highly negatively-charged (~23e), high dipole moment (1750 D) protein α, β- tubulin.
Aarat P. Kalra +9 more
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Measuring and modeling polymer concentration profiles near spindle boundaries argues that spindle microtubules regulate their own nucleation [PDF]
New Journal of Physics, 2018 Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regulation
Bryan Kaye +5 more
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A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases. [PDF]
PLoS Computational Biology, 2015 The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection of a neuron.
Chuan Xue, Blerta Shtylla, Anthony Brown
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A model for the orientational ordering of the plant microtubule cortical array [PDF]
, 2009 The plant microtubule cortical array is a striking feature of all growing plant cells. It consists of a more or less homogeneously distributed array of highly aligned microtubules connected to the inner side of the plasma membrane and oriented ...
Bela M. Mulder +7 more
core +2 more sources
Elastic properties of grafted microtubules [PDF]
PNAS 103, 10248 (2006), 2005 We use single-particle tracking to study the elastic properties of single microtubules grafted to a substrate. Thermal fluctuations of the free microtubule's end are recorded, in order to measure position distribution functions from which we calculate ...
A. Jonas +34 more
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On the Nature and Shape of Tubulin Trails: Implications on Microtubule Self-Organization [PDF]
Acta Biotheoretica 60, 1 (2012) 55, 2012 Microtubules, major elements of the cell skeleton are, most of the time, well organized in vivo, but they can also show self-organizing behaviors in time and/or space in purified solutions in vitro. Theoretical studies and models based on the concepts of
Glade, Nicolas
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Blocking microtubule deacetylation inhibits anaphase chromosome movements in crane-fly spermatocytes. [PDF]
PLoS ONEChromosome movement speeds during anaphase are regulated by depolymerization of microtubules. Several models describe chromosome movement during cell division but none of them consider post-translational modifications of tubulin, even though such ...
Maral Janan +2 more
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Lab-on-chip microscope platform for electro-manipulation of a dense microtubules network
Scientific Reports, 2022 Pulsed electric field (PEF) technology is promising for the manipulation of biomolecular components and has potential applications in biomedicine and bionanotechnology.
Daniel Havelka +5 more
doaj +1 more source
Ectopic A-lattice seams destabilize microtubules [PDF]
, 2014 Natural microtubules typically include one A-lattice seam within an otherwise helically symmetric B-lattice tube. It is currently unclear how A-lattice seams influence microtubule dynamic instability.
A des Georges +54 more
core +1 more source
Isolation of Microtubules and Microtubule Proteins
Current Protocols in Cell Biology, 2008 AbstractThis unit describes various protocols for the isolation and purification of the main constituents of microtubules, chiefly α‐ and β‐tubulin, and the most significant microtubule associated proteins (MAPs), specifically MAP1A, MAP1B, MAP2, and tau.
Ávila, Jesús +3 more
openaire +3 more sources