Results 21 to 30 of about 225,378 (345)
Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro. [PDF]
PLoS ONE, 2016 Microtubule structure and functions have been widely studied in vitro and in cells. Research has shown that cysteines on tubulin play a crucial role in the polymerization of microtubules.
Meenakshi Prabhune +3 more
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Nanomechanics of Microtubules [PDF]
Physical Review Letters, 2002 We have determined the mechanical anisotropy of a single microtubule by simultaneously measuring the Young's and the shear moduli in vitro. This was achieved by elastically deforming the microtubule deposited on a substrate tailored by electron-beam lithography with a tip of an atomic force microscope.
B. Babić +9 more
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Isolation of Microtubules and Microtubule Proteins
Current Protocols in Cell Biology, 2008 AbstractThis unit describes various protocols for the isolation and purification of the main constituents of microtubules, chiefly α‐ and β‐tubulin, and the most significant microtubule associated proteins (MAPs), specifically MAP1A, MAP1B, MAP2, and tau.
Ávila, Jesús +3 more
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Lab-on-chip microscope platform for electro-manipulation of a dense microtubules network
Scientific Reports, 2022 Pulsed electric field (PEF) technology is promising for the manipulation of biomolecular components and has potential applications in biomedicine and bionanotechnology.
Daniel Havelka +5 more
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Cell Motility and the Cytoskeleton, 1999 The regulation of microtubule stability by severing of the polymer along its length is a newly appreciated and potentially important mechanism for controlling microtubule function. Microtubule severing occurs in living cells, but direct observation of this event is infrequent.
L M, Quarmby, T A, Lohret
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2018 Various experiments have indicated that anaphase chromosomes continue to move after their kinetochore microtubules are severed. The chromosomes move poleward at an accelerated rate after the microtubules are cut but they slow down 1–3 min later and move ...
Arthur Forer +3 more
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Microtubules in cell migration
Essays in Biochemistry, 2019 Directed cell migration is critical for embryogenesis and organ development, wound healing and the immune response. Microtubules are dynamic polymers that control directional migration through a number of coordinated processes: microtubules are the ...
Clare L. Garcin, A. Straube
semanticscholar +1 more source
Microtubules, microtubule-interfering agents and apoptosis
Apoptosis, 2003 Microtubules are dynamic polymers that play crucial roles in a large number of cellular functions. Their pivotal role in mitosis makes them a target for the development of anticancer drugs. Microtubule-damaging agents suppress microtubule dynamics, leading to disruption of the mitotic spindle in dividing cells, cell cycle arrest at M phase, and late ...
Mollinedo, Faustino, Gajate, Consuelo
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Effect of viscoelastic medium on wave propagation along protein microtubules
AIP Advances, 2019 An Orthotropic Kelvin-like model is developed here to study wave dispersion relation along microtubules when they are embedded in viscoelastic material.
Muhammad Safeer +2 more
doaj +1 more source
The emerging role of microtubules in invasion plasticity
Frontiers in Oncology, 2023 The ability of cells to switch between different invasive modes during metastasis, also known as invasion plasticity, is an important characteristic of tumor cells that makes them able to resist treatment targeted to a particular invasion mode.
Anna Legátová +9 more
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