Results 21 to 30 of about 334,432 (342)
Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex Positioning. [PDF]
, 2017 The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion.
Agata Nawrotek +10 more
core +3 more sources
Microtubules acquire resistance from mechanical breakage through intralumenal acetylation
Science, 2017 Acetylation keeps microtubules strong Cells need microtubules for intracellular transport and to avoid being crushed. On investigating microtubule breakage in live fibroblasts, Xu et al.
Zhenjie Xu +8 more
semanticscholar +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010 Formins have recently been recognized as prominent regulators of the microtubule (MT) cytoskeleton where they modulate the dynamics of selected MTs in interphase and mitosis. The association of formins with the MT cytoskeleton and their action on MT dynamics are relatively unexplored areas, yet growing evidence supports a direct role in their ...
Gregg G. Gundersen, Francesca Bartolini
openaire +3 more sources
The Mating-specific Gα Interacts with a Kinesin-14 and Regulates Pheromone-induced Nuclear Migration in Budding Yeast [PDF]
, 2009 As a budding yeast cell elongates toward its mating partner, cytoplasmic microtubules connect the nucleus to the cell cortex at the growth tip.
Cooper, John A +6 more
core +4 more sources
Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape
Journal of Cell Biology, 1993 Microtubules are long, proteinaceous filaments that perform structural functions in eukaryotic cells by defining cellular shape and serving as tracks for intracellular motor proteins.
F. Gittes +3 more
semanticscholar +1 more source
A "MICROTUBULE" IN A BACTERIUM [PDF]
The Journal of Cell Biology, 1967 A study of the anchorage of the flagella in swarmers of Proteus mirabilis led to the incidental observation of microtubules. These microtubules were found in thin sections and in whole mount preparations of cells from which most of the content had been released by osmotic shock before staining negatively with potassium phosphotungstate (PTA).
Judith F. M. Hoeniger +2 more
openaire +3 more sources
Microtubules Gate Tau Condensation to Spatially Regulate Microtubule Functions
Nature Cell Biology, 2018 Tau is an abundant microtubule-associated protein in neurons. Tau aggregation into insoluble fibrils is a hallmark of Alzheimer’s disease and other types of dementia1, yet the physiological state of tau molecules within cells remains unclear.
Ruensern Tan +8 more
semanticscholar +1 more source
Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes
Nature Cell Biology, 2018 Tau is an intrinsically disordered protein, which diffuses on microtubules1. In neurodegenerative diseases, collectively termed tauopathies, malfunction of tau and its detachment from axonal microtubules are correlated with axonal degeneration2.
Valerie Siahaan +6 more
semanticscholar +1 more source
Molecular Biology of the Cell, 2018 The Minisymposium “The Life of a Microtubule: Birth, Dynamics and Function†highlighted new findings on how microtubules (MTs) are made, how their length and spatial organization is regulated, and finally how they contribute to cellular functions.
Dixit, Ram, Petry, Sabine
openaire +4 more sources
Diffusion of myosin V on microtubules [PDF]
, 2011 Organelle transport in eukaryotes employs both microtubule and actin tracks to deliver cargo effectively to their destinations, but the question of how the two systems cooperate is still largely unanswered.
Abdel Motaal, Basma +4 more
core +1 more source