Results 31 to 40 of about 249,538 (351)
Cell Motility and the Cytoskeleton, 1999 The regulation of microtubule stability by severing of the polymer along its length is a newly appreciated and potentially important mechanism for controlling microtubule function. Microtubule severing occurs in living cells, but direct observation of this event is infrequent.
L M, Quarmby, T A, Lohret
openaire +2 more sources
Effect of viscoelastic medium on wave propagation along protein microtubules
AIP Advances, 2019 An Orthotropic Kelvin-like model is developed here to study wave dispersion relation along microtubules when they are embedded in viscoelastic material.
Muhammad Safeer +2 more
doaj +1 more source
Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner. [PDF]
, 2019 The spindle assembly checkpoint (SAC) prevents anaphase until all kinetochores attach to the spindle. Each mammalian kinetochore binds many microtubules, but how many attached microtubules are required to turn off the checkpoint, and how the kinetochore ...
Akiyoshi +80 more
core +1 more source
Folia Histochemica et Cytobiologica, 2011 Lipotubuloids, structures containing lipid bodies and microtubules, are described in ovary epidermal cells of <i>Ornithogalum umbellatum</i>.
Agnieszka Wojtczak +4 more
doaj +1 more source
The emerging role of microtubules in invasion plasticity
Frontiers in Oncology, 2023 The ability of cells to switch between different invasive modes during metastasis, also known as invasion plasticity, is an important characteristic of tumor cells that makes them able to resist treatment targeted to a particular invasion mode.
Anna Legátová +9 more
doaj +1 more source
The Mating-specific Gα Interacts with a Kinesin-14 and Regulates Pheromone-induced Nuclear Migration in Budding Yeast [PDF]
, 2009 As a budding yeast cell elongates toward its mating partner, cytoplasmic microtubules connect the nucleus to the cell cortex at the growth tip.
Cooper, John A +6 more
core +4 more sources
Microtubules, microtubule-interfering agents and apoptosis
Apoptosis, 2003 Microtubules are dynamic polymers that play crucial roles in a large number of cellular functions. Their pivotal role in mitosis makes them a target for the development of anticancer drugs. Microtubule-damaging agents suppress microtubule dynamics, leading to disruption of the mitotic spindle in dividing cells, cell cycle arrest at M phase, and late ...
Mollinedo, Faustino, Gajate, Consuelo
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The regulatory effect of Tau protein on polymerization of MCF7 microtubules in vitro
Biochemistry and Biophysics Reports, 2019 Growing evidence continues to point toward the critical role of beta tubulin isotypes in regulating some intracellular functions. Changes that were observed in the microtubules’ intrinsic dynamics, the way they interact with some chemotherapeutic agents,
Mitra Shojania Feizabadi +3 more
doaj +1 more source
A Stochastic Multiscale Model That Explains the Segregation of Axonal Microtubules and Neurofilaments in Neurological Diseases. [PDF]
PLoS Computational Biology, 2015 The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection of a neuron.
Chuan Xue, Blerta Shtylla, Anthony Brown
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010 Formins have recently been recognized as prominent regulators of the microtubule (MT) cytoskeleton where they modulate the dynamics of selected MTs in interphase and mitosis. The association of formins with the MT cytoskeleton and their action on MT dynamics are relatively unexplored areas, yet growing evidence supports a direct role in their ...
Gregg G. Gundersen, Francesca Bartolini
openaire +3 more sources