Results 31 to 40 of about 225,378 (345)
Tubulin acetylation protects long-lived microtubules against mechanical aging
Nature Cell Biology, 2017 Long-lived microtubules endow the eukaryotic cell with long-range transport abilities. While long-lived microtubules are acetylated on Lys40 of α-tubulin (αK40), acetylation takes place after stabilization and does not protect against depolymerization ...
D. Portran +4 more
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Actin–microtubule coordination at growing microtubule ends [PDF]
Nature Communications, 2014 To power dynamic processes in cells, the actin and microtubule cytoskeletons organize into complex structures. Although it is known that cytoskeletal coordination is vital for cell function, the mechanisms by which cross-linking proteins coordinate actin and microtubule activities remain poorly understood.
Preciado López, Magdalena +6 more
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Microtubules acquire resistance from mechanical breakage through intralumenal acetylation
Science, 2017 Acetylation keeps microtubules strong Cells need microtubules for intracellular transport and to avoid being crushed. On investigating microtubule breakage in live fibroblasts, Xu et al.
Zhenjie Xu +8 more
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Folia Histochemica et Cytobiologica, 2011 Lipotubuloids, structures containing lipid bodies and microtubules, are described in ovary epidermal cells of <i>Ornithogalum umbellatum</i>.
Agnieszka Wojtczak +4 more
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Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure
Nature Network Boston, 2018 Detyrosinated microtubules provide mechanical resistance that can impede the motion of contracting cardiomyocytes. However, the functional effects of microtubule detyrosination in heart failure or in human hearts have not previously been studied.
C. Y. Chen +12 more
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010 Formins have recently been recognized as prominent regulators of the microtubule (MT) cytoskeleton where they modulate the dynamics of selected MTs in interphase and mitosis. The association of formins with the MT cytoskeleton and their action on MT dynamics are relatively unexplored areas, yet growing evidence supports a direct role in their ...
Gregg G. Gundersen, Francesca Bartolini
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A "MICROTUBULE" IN A BACTERIUM [PDF]
The Journal of Cell Biology, 1967 A study of the anchorage of the flagella in swarmers of Proteus mirabilis led to the incidental observation of microtubules. These microtubules were found in thin sections and in whole mount preparations of cells from which most of the content had been released by osmotic shock before staining negatively with potassium phosphotungstate (PTA).
Judith F. M. Hoeniger +2 more
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Flexural rigidity of microtubules and actin filaments measured from thermal fluctuations in shape
Journal of Cell Biology, 1993 Microtubules are long, proteinaceous filaments that perform structural functions in eukaryotic cells by defining cellular shape and serving as tracks for intracellular motor proteins.
F. Gittes +3 more
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Ukrainian Botanical Journal, 2020 Plants of Zea mays were grown for 12 days in sulfur-deficient medium according to a standard technique applied specifically for formation of aerenchyma cavities in the adventitious roots.
Shevchenko G.V.
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Microtubules Gate Tau Condensation to Spatially Regulate Microtubule Functions
Nature Cell Biology, 2018 Tau is an abundant microtubule-associated protein in neurons. Tau aggregation into insoluble fibrils is a hallmark of Alzheimer’s disease and other types of dementia1, yet the physiological state of tau molecules within cells remains unclear.
Ruensern Tan +8 more
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