Results 1 to 10 of about 7,989 (195)
Tp47-Induced Monocyte-Derived Microvesicles Promote the Adherence of THP-1 Cells to Human Umbilical Vein Endothelial Cells via an ERK1/2–NF-κB Signaling Cascade [PDF]
Microbiology Spectrum, 2023 The Treponema pallidum membrane protein Tp47 induces immunocyte adherence to vascular cells and contributes to vascular inflammation. However, it is unclear whether microvesicles are functional inflammatory mediators between vascular cells and ...
M. Wang +7 more
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R(h)oads to microvesicles [PDF]
Small GTPases, 2012 A novel form of cell-to-cell communication involving the formation and shedding of large vesicular structures, called microvesicles (MVs), from the surfaces of highly aggressive forms of human cancer cells has been attracting increasing amounts of attention. This is in large part due to the fact that MVs contain a variety of cargo that is not typically
Marc A. Antonyak +2 more
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The Immunomodulatory Role of Syncytiotrophoblast Microvesicles
PLoS ONE, 2011 Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards 'type 2' cytokine production ...
Jennifer H. Southcombe +3 more
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Microvesicles as immune orchestra conductors
Blood, 2008 In this issue of Blood, Sprague and colleagues report that platelet-derived membrane vesicles (PDMVs) orchestrate an immune response sufficient to deliver CD154 signals, which stimulate antigen-specific IgG production and modulate germinal-center formation, by cooperating with responses elucidated by CD4+ T cells.
Mariusz Z. Ratajczak
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Identification of Central Nervous System Oncologic Disease Biomarkers in EVs from Cerebrospinal Fluid (CSF) of Pediatric Patients: A Pilot Neuro-Proteomic Study [PDF]
Biomolecules, 2023 Cerebrospinal fluid (CSF) is a biochemical–clinical window into the brain. Unfortunately, its wide dynamic range, low protein concentration, and small sample quantity significantly limit the possibility of using it routinely.
Xhuliana Kajana +9 more
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Decoding the microvesicle message [PDF]
Nature Reviews Cancer, 2008 Isobel Barry
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The ins and outs of microvesicles [PDF]
FASEB BioAdvances, 2021 Microvesicles are a heterogeneous group of membrane-enclosed vesicles that are released from cells into the extracellular space by the outward budding and pinching of the plasma membrane. These vesicles are loaded with multiple selectively sorted proteins and nucleic acids.
James W. Clancy +2 more
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Neutrophil microvesicles and their role in disease [PDF]
The International Journal of Biochemistry & Cell Biology, 2021 Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo derived from their parental cell during formation, including proteases, micro-RNAs and lipids and ...
Reece Dow, Victoria Ridger
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Biomedicines, 2022 Exosomes/microvesicles originate from multivesicular bodies that allow the secretion of endolysosome components out of the cell. In the present work, we investigated the effects of rottlerin, a polyphenol, on exosome/microvesicle secretion in a model of ...
Yessenia L. Molina +10 more
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Microvesicles and Viral Infection [PDF]
Journal of Virology, 2011 ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
Nancy Raab-Traub, David G. Meckes
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